(35 nodes) Vitamin transmembrane transport network (Ursus maritimus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SCARB1	LOW QUALITY PROTEIN: scavenger receptor class B member 1; Belongs to the CD36 family. (500 aa)
	SLC52A3	Solute carrier family 52, riboflavin transporter, member 3. (472 aa)
	SLC2A8	Solute carrier family 2, facilitated glucose transporter member 8. (304 aa)
	RBP4	Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (189 aa)
	ABCG2	ATP-binding cassette sub-family G member 2 isoform X1. (649 aa)
	KANSL1L	KAT8 regulatory NSL complex subunit 1-like protein isoform X1. (988 aa)
	SLC2A10	Solute carrier family 2, facilitated glucose transporter member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (597 aa)
	SLC25A19	Mitochondrial thiamine pyrophosphate carrier isoform X2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa)
	FOLR1	Folate receptor alpha. (254 aa)
	ABCC5-2	Multidrug resistance-associated protein 5 isoform X1. (1181 aa)
	ABCC5	Multidrug resistance-associated protein 5 isoform X2. (208 aa)
	LOC103678492	Stimulated by retinoic acid gene 6 protein-like. (622 aa)
	SLC44A4	Choline transporter-like protein 4; Belongs to the CTL (choline transporter-like) family. (707 aa)
	SLC46A1	Solute carrier family 46 member 1. (451 aa)
	SLC27A1	Long-chain fatty acid transport protein 1. (668 aa)
	CCDC180	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 180. (1597 aa)
	SLC23A1	LOW QUALITY PROTEIN: solute carrier family 23 member 1. (598 aa)
	CCDC181	Coiled-coil domain-containing protein 181. (501 aa)
	SLC19A2	Thiamine transporter 1. (454 aa)
	SLC19A3	Thiamine transporter 2. (506 aa)
	LOC103662857	Thiamine transporter 2-like. (494 aa)
	LOC103678264	Solute carrier family 23 member 1-like isoform X2. (614 aa)
	LRP2	Low-density lipoprotein receptor-related protein 2. (403 aa)
	RTBDN	Retbindin. (223 aa)
	GC	Vitamin D-binding protein. (561 aa)
	SLC22A13	Solute carrier family 22 member 13 isoform X2. (510 aa)
	SLC22A14	Solute carrier family 22 member 14. (600 aa)
	STRA6	LOW QUALITY PROTEIN: stimulated by retinoic acid gene 6 protein homolog. (630 aa)
	SLC23A2	Solute carrier family 23 member 2. (616 aa)
	ENSUMAP00000018664	annotation not available (401 aa)
	SLC2A2	Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (531 aa)
	ABCD4	ATP-binding cassette sub-family D member 4. (565 aa)
	SLC25A32	Mitochondrial folate transporter/carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
	SLC52A1	Solute carrier family 52, riboflavin transporter, member 2. (445 aa)
	SLC5A6	Sodium-dependent multivitamin transporter isoform X4; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (638 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC5	ABCC5-2	ENSUMAP00000008491	ENSUMAP00000008496	Multidrug resistance-associated protein 5 isoform X2.	Multidrug resistance-associated protein 5 isoform X1.	0.922
ABCC5	ABCD4	ENSUMAP00000008491	ENSUMAP00000011819	Multidrug resistance-associated protein 5 isoform X2.	ATP-binding cassette sub-family D member 4.	0.461
ABCC5-2	ABCC5	ENSUMAP00000008496	ENSUMAP00000008491	Multidrug resistance-associated protein 5 isoform X1.	Multidrug resistance-associated protein 5 isoform X2.	0.922
ABCC5-2	ABCD4	ENSUMAP00000008496	ENSUMAP00000011819	Multidrug resistance-associated protein 5 isoform X1.	ATP-binding cassette sub-family D member 4.	0.461
ABCD4	ABCC5	ENSUMAP00000011819	ENSUMAP00000008491	ATP-binding cassette sub-family D member 4.	Multidrug resistance-associated protein 5 isoform X2.	0.461
ABCD4	ABCC5-2	ENSUMAP00000011819	ENSUMAP00000008496	ATP-binding cassette sub-family D member 4.	Multidrug resistance-associated protein 5 isoform X1.	0.461
CCDC180	LOC103678492	ENSUMAP00000015919	ENSUMAP00000015860	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 180.	Stimulated by retinoic acid gene 6 protein-like.	0.565
CCDC181	SLC19A2	ENSUMAP00000023953	ENSUMAP00000023959	Coiled-coil domain-containing protein 181.	Thiamine transporter 1.	0.432
ENSUMAP00000018664	GC	ENSUMAP00000018664	ENSUMAP00000007425	annotation not available	Vitamin D-binding protein.	0.592
FOLR1	SLC46A1	ENSUMAP00000010419	ENSUMAP00000016402	Folate receptor alpha.	Solute carrier family 46 member 1.	0.532
GC	ENSUMAP00000018664	ENSUMAP00000007425	ENSUMAP00000018664	Vitamin D-binding protein.	annotation not available	0.592
GC	LRP2	ENSUMAP00000007425	ENSUMAP00000018712	Vitamin D-binding protein.	Low-density lipoprotein receptor-related protein 2.	0.592
GC	RBP4	ENSUMAP00000007425	ENSUMAP00000004897	Vitamin D-binding protein.	Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma.	0.823
LOC103662857	SLC19A2	ENSUMAP00000024007	ENSUMAP00000023959	Thiamine transporter 2-like.	Thiamine transporter 1.	0.903
LOC103662857	SLC19A3	ENSUMAP00000024007	ENSUMAP00000024006	Thiamine transporter 2-like.	Thiamine transporter 2.	0.900
LOC103678264	SLC23A1	ENSUMAP00000020962	ENSUMAP00000021596	Solute carrier family 23 member 1-like isoform X2.	LOW QUALITY PROTEIN: solute carrier family 23 member 1.	0.903
LOC103678492	CCDC180	ENSUMAP00000015860	ENSUMAP00000015919	Stimulated by retinoic acid gene 6 protein-like.	LOW QUALITY PROTEIN: coiled-coil domain-containing protein 180.	0.565
LRP2	GC	ENSUMAP00000018712	ENSUMAP00000007425	Low-density lipoprotein receptor-related protein 2.	Vitamin D-binding protein.	0.592
RBP4	GC	ENSUMAP00000004897	ENSUMAP00000007425	Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma.	Vitamin D-binding protein.	0.823
RBP4	STRA6	ENSUMAP00000004897	ENSUMAP00000006695	Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma.	LOW QUALITY PROTEIN: stimulated by retinoic acid gene 6 protein homolog.	0.977