STRINGSTRING
FZD3 FZD3 SFRP2 SFRP2 SCRIB SCRIB TP63 TP63 LRRC1 LRRC1 CHST11 CHST11 AXIN1 AXIN1 MED12 MED12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
SFRP2Secreted frizzled-related protein 2. (299 aa)
SCRIBLOW QUALITY PROTEIN: protein scribble homolog. (844 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
LRRC1Leucine-rich repeat-containing protein 1. (493 aa)
CHST11Carbohydrate sulfotransferase. (132 aa)
AXIN1Axin-1 isoform X2. (867 aa)
MED12LOW QUALITY PROTEIN: mediator of RNA polymerase II transcription subunit 12. (2045 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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