24 items (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STAT5B	Signal transducer and activator of transcription. (787 aa)
	RIPK3	Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily. (487 aa)
	RC3H1	Ring finger and CCCH-type domains 1. (1133 aa)
	SLC46A2	Thymic stromal cotransporter homolog. (468 aa)
	GIMAP5	GTPase IMAP family member 5 isoform X1. (488 aa)
	LGALS2	Galectin. (132 aa)
	ZC3H8	Zinc finger CCCH domain-containing protein 8 isoform X1. (305 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (534 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	PPP2R3C	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X3. (450 aa)
	NCKAP1L	Nck-associated protein 1-like. (1134 aa)
	STAT5A	Signal transducer and activator of transcription. (793 aa)
	IL20RB	Interleukin-20 receptor subunit beta isoform X2. (392 aa)
	RC3H2	Ring finger and CCCH-type domains 2. (1189 aa)
	SIT1	Signaling threshold regulating transmembrane adaptor 1. (176 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (840 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (601 aa)
	SLC39A3	Solute carrier family 39 member 3. (314 aa)
	FADD	FAS-associated death domain protein. (192 aa)
	BCL2L11	Bcl-2-like protein 11 isoform X11. (84 aa)
	FOXN1	LOW QUALITY PROTEIN: forkhead box protein N1. (628 aa)
	IL2RA	Interleukin-2 receptor subunit alpha isoform X1. (267 aa)
	FAS	Tumor necrosis factor receptor superfamily member 6 isoform X1. (351 aa)
	TCIRG1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (218 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FADD	FAS	ENSUMAP00000009429	ENSUMAP00000016893	FAS-associated death domain protein.	Tumor necrosis factor receptor superfamily member 6 isoform X1.	0.999
FADD	RIPK3	ENSUMAP00000009429	ENSUMAP00000031815	FAS-associated death domain protein.	Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily.	0.994
FAS	FADD	ENSUMAP00000016893	ENSUMAP00000009429	Tumor necrosis factor receptor superfamily member 6 isoform X1.	FAS-associated death domain protein.	0.999
FAS	RIPK3	ENSUMAP00000016893	ENSUMAP00000031815	Tumor necrosis factor receptor superfamily member 6 isoform X1.	Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily.	0.476
IL2RA	STAT5A	ENSUMAP00000016645	ENSUMAP00000034681	Interleukin-2 receptor subunit alpha isoform X1.	Signal transducer and activator of transcription.	0.954
IL2RA	STAT5B	ENSUMAP00000016645	ENSUMAP00000032319	Interleukin-2 receptor subunit alpha isoform X1.	Signal transducer and activator of transcription.	0.954
PPP2R3C	PPP3CB	ENSUMAP00000015268	ENSUMAP00000013093	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X3.	Serine/threonine-protein phosphatase.	0.407
PPP3CB	PPP2R3C	ENSUMAP00000013093	ENSUMAP00000015268	Serine/threonine-protein phosphatase.	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X3.	0.407
RC3H1	RC3H2	ENSUMAP00000027678	ENSUMAP00000004038	Ring finger and CCCH-type domains 1.	Ring finger and CCCH-type domains 2.	0.560
RC3H2	RC3H1	ENSUMAP00000004038	ENSUMAP00000027678	Ring finger and CCCH-type domains 2.	Ring finger and CCCH-type domains 1.	0.560
RIPK3	FADD	ENSUMAP00000031815	ENSUMAP00000009429	Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily.	FAS-associated death domain protein.	0.994
RIPK3	FAS	ENSUMAP00000031815	ENSUMAP00000016893	Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily.	Tumor necrosis factor receptor superfamily member 6 isoform X1.	0.476
STAT5A	IL2RA	ENSUMAP00000034681	ENSUMAP00000016645	Signal transducer and activator of transcription.	Interleukin-2 receptor subunit alpha isoform X1.	0.954
STAT5A	STAT5B	ENSUMAP00000034681	ENSUMAP00000032319	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.997
STAT5B	IL2RA	ENSUMAP00000032319	ENSUMAP00000016645	Signal transducer and activator of transcription.	Interleukin-2 receptor subunit alpha isoform X1.	0.954
STAT5B	STAT5A	ENSUMAP00000032319	ENSUMAP00000034681	Signal transducer and activator of transcription.	Signal transducer and activator of transcription.	0.997