(12 nodes) Nuclear pore nuclear basket network (Ursus maritimus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAD1L1	LOW QUALITY PROTEIN: mitotic spindle assembly checkpoint protein MAD1. (706 aa)
	PCID2	PCI domain-containing protein 2 isoform X2. (390 aa)
	TPR	Nucleoprotein TPR. (2425 aa)
	CETN2	Centrin 2. (163 aa)
	MCM3AP	LOW QUALITY PROTEIN: germinal-center associated nuclear protein. (1978 aa)
	RANBP2	E3 SUMO-protein ligase RanBP2. (439 aa)
	ENY2	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (158 aa)
	NUP153	LOW QUALITY PROTEIN: nuclear pore complex protein Nup153. (1431 aa)
	NUP35	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (306 aa)
	NUP98	Nuclear pore complex protein Nup98-Nup96 isoform X1. (1817 aa)
	CETN3	Centrin-3. (167 aa)
	MAD2L1	Mitotic spindle assembly checkpoint protein MAD2A isoform X2. (195 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CETN2	CETN3	ENSUMAP00000030114	ENSUMAP00000006813	Centrin 2.	Centrin-3.	0.500
CETN2	ENY2	ENSUMAP00000030114	ENSUMAP00000027653	Centrin 2.	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	0.876
CETN2	MCM3AP	ENSUMAP00000030114	ENSUMAP00000035312	Centrin 2.	LOW QUALITY PROTEIN: germinal-center associated nuclear protein.	0.753
CETN2	NUP153	ENSUMAP00000030114	ENSUMAP00000024132	Centrin 2.	LOW QUALITY PROTEIN: nuclear pore complex protein Nup153.	0.614
CETN2	NUP98	ENSUMAP00000030114	ENSUMAP00000008884	Centrin 2.	Nuclear pore complex protein Nup98-Nup96 isoform X1.	0.410
CETN2	PCID2	ENSUMAP00000030114	ENSUMAP00000029318	Centrin 2.	PCI domain-containing protein 2 isoform X2.	0.925
CETN2	TPR	ENSUMAP00000030114	ENSUMAP00000030045	Centrin 2.	Nucleoprotein TPR.	0.490
CETN3	CETN2	ENSUMAP00000006813	ENSUMAP00000030114	Centrin-3.	Centrin 2.	0.500
CETN3	ENY2	ENSUMAP00000006813	ENSUMAP00000027653	Centrin-3.	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	0.975
CETN3	MAD2L1	ENSUMAP00000006813	ENSUMAP00000004602	Centrin-3.	Mitotic spindle assembly checkpoint protein MAD2A isoform X2.	0.462
CETN3	MCM3AP	ENSUMAP00000006813	ENSUMAP00000035312	Centrin-3.	LOW QUALITY PROTEIN: germinal-center associated nuclear protein.	0.985
CETN3	NUP153	ENSUMAP00000006813	ENSUMAP00000024132	Centrin-3.	LOW QUALITY PROTEIN: nuclear pore complex protein Nup153.	0.614
CETN3	NUP98	ENSUMAP00000006813	ENSUMAP00000008884	Centrin-3.	Nuclear pore complex protein Nup98-Nup96 isoform X1.	0.451
CETN3	PCID2	ENSUMAP00000006813	ENSUMAP00000029318	Centrin-3.	PCI domain-containing protein 2 isoform X2.	0.819
CETN3	TPR	ENSUMAP00000006813	ENSUMAP00000030045	Centrin-3.	Nucleoprotein TPR.	0.644
ENY2	CETN2	ENSUMAP00000027653	ENSUMAP00000030114	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	Centrin 2.	0.876
ENY2	CETN3	ENSUMAP00000027653	ENSUMAP00000006813	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	Centrin-3.	0.975
ENY2	MCM3AP	ENSUMAP00000027653	ENSUMAP00000035312	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	LOW QUALITY PROTEIN: germinal-center associated nuclear protein.	0.983
ENY2	NUP153	ENSUMAP00000027653	ENSUMAP00000024132	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	LOW QUALITY PROTEIN: nuclear pore complex protein Nup153.	0.697
ENY2	PCID2	ENSUMAP00000027653	ENSUMAP00000029318	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	PCI domain-containing protein 2 isoform X2.	0.936