STRINGSTRING
PRICKLE1 PRICKLE1 MAP3K5 MAP3K5 HIF1AN HIF1AN SOSTDC1 SOSTDC1 CCL17 CCL17 SOX8 SOX8 TMEM182 TMEM182 LRRC8A LRRC8A RIPOR2 RIPOR2 DDIT3 DDIT3 MSTN MSTN CXCL14 CXCL14 BMP4 BMP4 TNF TNF CMTM5 CMTM5 KLHL41 KLHL41 SRA1 SRA1 ID3 ID3 TRIP4 TRIP4 MBNL3 MBNL3 RANBP3L RANBP3L FLOT2 FLOT2 TNFSF14 TNFSF14 XKR8 XKR8 TBX3 TBX3 KAT5 KAT5 PPARD PPARD MAPK14 MAPK14 ZFP36L1 ZFP36L1 IGFBP3 IGFBP3 DLL1 DLL1 SMYD1 SMYD1 CXCL10 CXCL10 CXCL9 CXCL9 LOC103677394 LOC103677394 MYOG MYOG MEF2C MEF2C BOC BOC MYF6 MYF6 MYF5 MYF5 CDON CDON
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRICKLE1Prickle-like protein 1. (804 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1768 aa)
HIF1ANHypoxia-inducible factor 1-alpha inhibitor. (373 aa)
SOSTDC1Sclerostin domain-containing protein 1. (206 aa)
CCL17C-C motif chemokine. (109 aa)
SOX8Transcription factor SOX-8. (216 aa)
TMEM182Transmembrane protein 182 isoform X1. (229 aa)
LRRC8AVolume-regulated anion channel subunit LRRC8A. (835 aa)
RIPOR2Protein FAM65B. (974 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
MSTNGrowth/differentiation factor 8. (368 aa)
CXCL14C-X-C motif chemokine ligand 14. (153 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CMTM5CKLF-like MARVEL transmembrane domain-containing protein 5. (233 aa)
KLHL41Kelch like family member 41. (606 aa)
SRA1Steroid receptor RNA activator 1. (266 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
TRIP4Activating signal cointegrator 1 isoform X1. (581 aa)
MBNL3Muscleblind-like protein 3. (346 aa)
RANBP3LRan-binding protein 3-like isoform X1. (491 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (515 aa)
TNFSF14Tumor necrosis factor ligand superfamily member 14; Belongs to the tumor necrosis factor family. (245 aa)
XKR8XK-related protein. (244 aa)
TBX3LOW QUALITY PROTEIN: T-box transcription factor TBX3. (130 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (505 aa)
PPARDLOW QUALITY PROTEIN: peroxisome proliferator-activated receptor delta. (397 aa)
MAPK14Mitogen-activated protein kinase. (362 aa)
ZFP36L1Zinc finger protein 36, C3H1 type-like 1. (338 aa)
IGFBP3Insulin-like growth factor-binding protein 3. (102 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (695 aa)
SMYD1Histone-lysine N-methyltransferase SMYD1. (489 aa)
CXCL10C-X-C motif chemokine. (98 aa)
CXCL9C-X-C motif chemokine 9 isoform X1. (153 aa)
LOC103677394Transforming growth factor beta-1. (299 aa)
MYOGMyogenin. (208 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X3. (433 aa)
BOCLOW QUALITY PROTEIN: brother of CDO. (1161 aa)
MYF6LOW QUALITY PROTEIN: myogenic factor 6. (225 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes isoform X1. (1271 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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