STRINGSTRING
DLL1 DLL1 KCNA1 KCNA1 EGR2 EGR2 HSPA5 HSPA5 KIF14 KIF14 NRP2 NRP2 SEMA3F SEMA3F TFAP2A TFAP2A HOXB1 HOXB1 BMPR1A BMPR1A KCNA2 KCNA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (695 aa)
KCNA1Potassium Voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
EGR2LOW QUALITY PROTEIN: E3 SUMO-protein ligase EGR2. (323 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
KIF14Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1630 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
SEMA3Fsemaphorin-3F; Belongs to the semaphorin family. (578 aa)
TFAP2ALOW QUALITY PROTEIN: transcription factor AP-2-alpha. (494 aa)
HOXB1Homeobox protein Hox-B1. (301 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
KCNA2Potassium Voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (22%) [HD]