STRINGSTRING
SAV1 SAV1 PDCD10 PDCD10 LOC103665211 LOC103665211 ATF7IP ATF7IP HSP90AA1 HSP90AA1 CREBL2 CREBL2 LOC103682075 LOC103682075 GET1 GET1 TBRG1 TBRG1 MT3 MT3 DSG1 DSG1 TREX1 TREX1 PEX19 PEX19 RPAP3 RPAP3 CLU CLU CCT7 CCT7 BAG3 BAG3 PHB2 PHB2 USP7 USP7 CD74 CD74 RASSF2 RASSF2 HIP1R HIP1R CCNH CCNH HSP90AB1 HSP90AB1 DVL3 DVL3 CALR CALR ENSUMAP00000007957 ENSUMAP00000007957 USP33 USP33 C10orf90 C10orf90 WNT10B WNT10B AFM AFM ZSWIM7 ZSWIM7 CRYAB CRYAB SMO SMO FBXW9 FBXW9 MARCHF7 MARCHF7 USP13 USP13 PDCL3 PDCL3 CDK7 CDK7 PIK3R1 PIK3R1 SYVN1 SYVN1 HYPK HYPK BAG4 BAG4 PEX6 PEX6 WDR81 WDR81 COG7 COG7 IFI30 IFI30 LOC103680202 LOC103680202 PIM1 PIM1 ENSUMAP00000013971 ENSUMAP00000013971 A1CF A1CF STX12 STX12 MFSD1 MFSD1 FLOT2 FLOT2 PARK2 PARK2 ENSUMAP00000015922 ENSUMAP00000015922 PARK2-2 PARK2-2 TCP1 TCP1 NLK NLK PFN2 PFN2 PTEN PTEN PPIB PPIB HIP1 HIP1 ATP1B3 ATP1B3 GRN GRN USP36 USP36 SUGT1 SUGT1 BAG6 BAG6 NAA16 NAA16 AHSP AHSP NAA15 NAA15 ZNF207 ZNF207 LOC103672401 LOC103672401 HPS4 HPS4 LOC103667265 LOC103667265 PHB PHB CHEK2 CHEK2 COG3 COG3 FBXW7 FBXW7 ENSUMAP00000022411 ENSUMAP00000022411 TSC1 TSC1 PRKRA PRKRA RTN4 RTN4 ATP1B2 ATP1B2 TP53 TP53 STK3 STK3 SAXO1 SAXO1 TRIM44 TRIM44 CAMLG CAMLG CDC37L1 CDC37L1 CCT3 CCT3 GLMP GLMP EPHA4 EPHA4 CTNND1 CTNND1 BAG2 BAG2 PINK1 PINK1 MUL1 MUL1 OTUD3 OTUD3 TRIM39-RPP21 TRIM39-RPP21 ASDURF ASDURF CLUL1 CLUL1 FLOT1 FLOT1 TAF9B TAF9B TRIM61 TRIM61 LOC103658131 LOC103658131 LOC103658124 LOC103658124 LOC103658125 LOC103658125 ENSUMAP00000027960 ENSUMAP00000027960 STXBP4 STXBP4 USP9X USP9X MORC3 MORC3 FLNA FLNA CCT2 CCT2 LAMP1 LAMP1 CCT4 CCT4 TTI2 TTI2 TMEM19 TMEM19 LOC103656900 LOC103656900 LOC103671807 LOC103671807 AAK1 AAK1 TELO2 TELO2 EP300 EP300 LAMP2 LAMP2 PLPP3 PLPP3 ENSUMAP00000030897 ENSUMAP00000030897 ENSUMAP00000031254 ENSUMAP00000031254 CREB1 CREB1 WFS1 WFS1 ENSUMAP00000031854 ENSUMAP00000031854 USP19 USP19 USP2 USP2 NOP53 NOP53 TSPAN1 TSPAN1 APOA2 APOA2 PARK7 PARK7 ENSUMAP00000033644 ENSUMAP00000033644 P3H1 P3H1 COA8 COA8 CDC37 CDC37 PIN1 PIN1 RABL3 RABL3 STK4 STK4 CRYAA CRYAA GOLGA7 GOLGA7 LOC103677095 LOC103677095
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SAV1Salvador family WW domain containing protein 1. (351 aa)
PDCD10Programmed cell death protein 10. (212 aa)
LOC103665211Mothers against decapentaplegic homolog. (244 aa)
ATF7IPActivating transcription factor 7-interacting protein 1 isoform X2. (1257 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (733 aa)
CREBL2cAMP-responsive element-binding protein-like 2. (120 aa)
LOC103682075Segment polarity protein dishevelled homolog DVL-1-like. (893 aa)
GET1Guided entry of tail-anchored proteins factor 1. (256 aa)
TBRG1Transforming growth factor beta regulator 1. (260 aa)
MT3Metallothionein 3. (68 aa)
DSG1Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1036 aa)
TREX1Three-prime repair exonuclease 1. (314 aa)
PEX19Peroxisomal biogenesis factor 19. (275 aa)
RPAP3RNA polymerase II-associated protein 3. (663 aa)
CLUClusterin; Belongs to the clusterin family. (476 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (543 aa)
BAG3BAG family molecular chaperone regulator 3. (551 aa)
PHB2Prohibitin. (297 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1086 aa)
CD74LOW QUALITY PROTEIN: HLA class II histocompatibility antigen gamma chain. (279 aa)
RASSF2Ras association domain-containing protein 2 isoform X2. (326 aa)
HIP1RHuntingtin-interacting protein 1-related protein. (915 aa)
CCNHcyclin-H isoform X1; Belongs to the cyclin family. (329 aa)
HSP90AB1Heat shock protein HSP 90-beta. (699 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3. (423 aa)
CALRCalreticulin. (417 aa)
ENSUMAP00000007957annotation not available (154 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (912 aa)
C10orf90Centrosomal protein C10orf90 homolog. (641 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
AFMAfamin. (607 aa)
ZSWIM7Zinc finger SWIM domain-containing protein 7. (100 aa)
CRYABAlpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (745 aa)
FBXW9F-box/WD repeat-containing protein 9. (367 aa)
MARCHF7E3 ubiquitin-protein ligase MARCH7 isoform X1. (708 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (798 aa)
PDCL3Phosducin-like protein 3. (240 aa)
CDK7Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
SYVN1E3 ubiquitin-protein ligase synoviolin. (573 aa)
HYPKHuntingtin-interacting protein K. (121 aa)
BAG4BAG family molecular chaperone regulator 4 isoform X1. (457 aa)
PEX6LOW QUALITY PROTEIN: peroxisome biogenesis factor 6. (796 aa)
WDR81LOW QUALITY PROTEIN: WD repeat-containing protein 81. (1860 aa)
COG7LOW QUALITY PROTEIN: conserved oligomeric Golgi complex subunit 7. (754 aa)
IFI30Gamma-interferon-inducible lysosomal thiol reductase. (244 aa)
LOC103680202Probable ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2531 aa)
PIM1Serine/threonine-protein kinase pim-1. (294 aa)
ENSUMAP00000013971annotation not available (193 aa)
A1CFAPOBEC1 complementation factor. (590 aa)
STX12Syntaxin-12; Belongs to the syntaxin family. (259 aa)
MFSD1Major facilitator superfamily domain-containing protein 1 isoform X1. (481 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (515 aa)
PARK2E3 ubiquitin-protein ligase parkin isoform X5. (153 aa)
ENSUMAP00000015922annotation not available (110 aa)
PARK2-2E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (176 aa)
TCP1T-complex protein 1 subunit alpha. (556 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (515 aa)
PFN2Profilin; Belongs to the profilin family. (98 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (565 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
HIP1Huntingtin-interacting protein 1. (1000 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (296 aa)
GRNGranulins isoform X1. (724 aa)
USP36LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 36; Belongs to the peptidase C19 family. (1103 aa)
SUGT1Suppressor of G2 allele of SKP1 homolog. (300 aa)
BAG6Large proline-rich protein BAG6. (1108 aa)
NAA16N(alpha)-acetyltransferase 16, NatA auxiliary subunit. (839 aa)
AHSPAlpha-hemoglobin-stabilizing protein. (90 aa)
NAA15N-alpha-acetyltransferase 15, NatA auxiliary subunit. (816 aa)
ZNF207BUB3-interacting and GLEBS motif-containing protein ZNF207. (448 aa)
LOC103672401LOW QUALITY PROTEIN: heat shock protein HSP 90-beta-like. (91 aa)
HPS4Hermansky-Pudlak syndrome 4 protein. (657 aa)
LOC103667265LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (237 aa)
PHBProhibitin. (265 aa)
CHEK2Serine/threonine-protein kinase Chk2 isoform X2. (542 aa)
COG3Conserved oligomeric Golgi complex subunit 3. (826 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform X1. (706 aa)
ENSUMAP00000022411annotation not available (78 aa)
TSC1Hamartin. (1168 aa)
PRKRAInterferon-inducible double-stranded RNA-dependent protein kinase activator A. (288 aa)
RTN4Reticulon. (978 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (237 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
STK3Serine/threonine-protein kinase 3. (497 aa)
SAXO1Protein FAM154A. (470 aa)
TRIM44Tripartite motif-containing protein 44. (516 aa)
CAMLGCalcium signal-modulating cyclophilin ligand. (290 aa)
CDC37L1Hsp90 co-chaperone Cdc37-like 1. (336 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
GLMPLOW QUALITY PROTEIN: lysosomal protein NCU-G1. (380 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (911 aa)
CTNND1Catenin delta-1 isoform X1. (932 aa)
BAG2BAG family molecular chaperone regulator 2. (220 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (533 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (252 aa)
OTUD3OTU domain-containing protein 3. (396 aa)
TRIM39-RPP21E3 ubiquitin-protein ligase TRIM39 isoform X2. (469 aa)
ASDURFASNSD1 upstream reading frame. (96 aa)
CLUL1Clusterin; Belongs to the clusterin family. (464 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
TAF9BTranscription initiation factor TFIID subunit 9B. (252 aa)
TRIM61Tripartite motif-containing protein 60-like. (216 aa)
LOC103658131Putative tripartite motif-containing protein 75. (105 aa)
LOC103658124Tripartite motif-containing protein 60-like. (200 aa)
LOC103658125Putative tripartite motif-containing protein 75. (309 aa)
ENSUMAP00000027960annotation not available (155 aa)
STXBP4Syntaxin-binding protein 4 isoform X2. (565 aa)
USP9XLOW QUALITY PROTEIN: probable ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2463 aa)
MORC3MORC family CW-type zinc finger protein 3. (927 aa)
FLNAfilamin-A. (2549 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
LAMP1Lysosome-associated membrane glycoprotein 1. (406 aa)
CCT4T-complex protein 1 subunit delta. (561 aa)
TTI2TELO2-interacting protein 2. (508 aa)
TMEM19Transmembrane protein 19 isoform X1. (363 aa)
LOC103656900LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (280 aa)
LOC103671807Uncharacterized protein FLJ45252-like. (607 aa)
AAK1AP2-associated protein kinase 1. (516 aa)
TELO2Telomere length regulation protein TEL2 homolog. (791 aa)
EP300LOW QUALITY PROTEIN: histone acetyltransferase p300. (2390 aa)
LAMP2Lysosome-associated membrane glycoprotein 2. (363 aa)
PLPP3Lipid phosphate phosphohydrolase 3. (273 aa)
ENSUMAP00000030897annotation not available (310 aa)
ENSUMAP00000031254Glyceraldehyde-3-phosphate dehydrogenase-like. (197 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
WFS1LOW QUALITY PROTEIN: wolframin. (853 aa)
ENSUMAP00000031854annotation not available (215 aa)
USP19LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 19. (1192 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (558 aa)
NOP53Glioma tumor suppressor candidate region gene 2 protein. (356 aa)
TSPAN1Tetraspanin. (241 aa)
APOA2Apolipoprotein A-II. (111 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
ENSUMAP00000033644annotation not available (237 aa)
P3H1Prolyl 3-hydroxylase 1. (784 aa)
COA8Cytochrome c oxidase assembly factor 8. (234 aa)
CDC37Hsp90 co-chaperone Cdc37. (227 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (133 aa)
RABL3RAB, member of RAS oncogene family like 3. (264 aa)
STK4Serine/threonine-protein kinase 4. (496 aa)
CRYAAAlpha-crystallin A chain; Belongs to the small heat shock protein (HSP20) family. (177 aa)
GOLGA7Golgin subfamily A member 7. (137 aa)
LOC103677095LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (243 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
Server load: low (22%) [HD]