(13 nodes) Cardiac muscle cell proliferation network (Ursus maritimus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARID2	LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 2. (1411 aa)
	PRKAR1A	Protein kinase cAMP-dependent type I regulatory subunit alpha. (409 aa)
	WNT2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
	SAV1	Salvador family WW domain containing protein 1. (351 aa)
	PRKAR1B	LOW QUALITY PROTEIN: cAMP-dependent protein kinase type I-beta regulatory subunit. (412 aa)
	TBX5	T-box transcription factor TBX5. (474 aa)
	TENM4	Teneurin-4-like. (2643 aa)
	DIPK2A	Deleted in autism protein 1. (290 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	JARID2	LOW QUALITY PROTEIN: protein Jumonji. (1137 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	TBX5	ENSUMAP00000029171	ENSUMAP00000014718	Bone morphogenetic protein 10.	T-box transcription factor TBX5.	0.464
FGF9	TGFB2	ENSUMAP00000020627	ENSUMAP00000028351	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.458
PRKAR1A	PRKAR1B	ENSUMAP00000001022	ENSUMAP00000007565	Protein kinase cAMP-dependent type I regulatory subunit alpha.	LOW QUALITY PROTEIN: cAMP-dependent protein kinase type I-beta regulatory subunit.	0.921
PRKAR1B	PRKAR1A	ENSUMAP00000007565	ENSUMAP00000001022	LOW QUALITY PROTEIN: cAMP-dependent protein kinase type I-beta regulatory subunit.	Protein kinase cAMP-dependent type I regulatory subunit alpha.	0.921
SMAD1	TENM4	ENSUMAP00000021317	ENSUMAP00000015658	Mothers against decapentaplegic homolog.	Teneurin-4-like.	0.443
TBX5	BMP10	ENSUMAP00000014718	ENSUMAP00000029171	T-box transcription factor TBX5.	Bone morphogenetic protein 10.	0.464
TBX5	WNT2	ENSUMAP00000014718	ENSUMAP00000003564	T-box transcription factor TBX5.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.424
TENM4	SMAD1	ENSUMAP00000015658	ENSUMAP00000021317	Teneurin-4-like.	Mothers against decapentaplegic homolog.	0.443
TGFB2	FGF9	ENSUMAP00000028351	ENSUMAP00000020627	Transforming growth factor beta; Belongs to the TGF-beta family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.458
WNT2	TBX5	ENSUMAP00000003564	ENSUMAP00000014718	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	T-box transcription factor TBX5.	0.424