STRINGSTRING
KCNJ8 KCNJ8 PKP2 PKP2 GSN GSN MYL3 MYL3 MAP2K3 MAP2K3 SCN5A SCN5A KCNQ1 KCNQ1 MYL2 MYL2 MAP2K6 MAP2K6 KCNA5 KCNA5 KCNJ2 KCNJ2 PIK3CA PIK3CA NUP155 NUP155 GJA5 GJA5 KCNE3 KCNE3 MYL10 MYL10 GRK2 GRK2 RYR2 RYR2 CACNB2 CACNB2 GAA GAA MYH6 MYH6 MYH7 MYH7 MYL4 MYL4 CACNA2D1 CACNA2D1 SMAD5 SMAD5 TCAP TCAP TNNI3 TNNI3 KCNJ5 KCNJ5 SGCD SGCD TNNI1 TNNI1 SCN4B SCN4B SCN2B SCN2B ABCC9 ABCC9 VEGFB VEGFB MTOR MTOR SCN3B SCN3B TNNC1 TNNC1 CSRP3 CSRP3 CACNA1D CACNA1D KCNE1 KCNE1 KCNE2 KCNE2 SCN1B SCN1B KCNH2 KCNH2 KCNE4 KCNE4 ENSUMAP00000015803 ENSUMAP00000015803 CACNA1C CACNA1C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
PKP2Plakophilin-2. (839 aa)
GSNGelsolin isoform X1. (748 aa)
MYL3Myosin light chain 3. (224 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2011 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (410 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (205 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
KCNA5LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (583 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (428 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
NUP155Nuclear pore complex protein Nup155. (1391 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa)
MYL10Myosin regulatory light chain 10. (217 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (636 aa)
RYR2Ryanodine receptor 2. (4923 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2. (613 aa)
GAALysosomal alpha-glucosidase. (944 aa)
MYH6LOW QUALITY PROTEIN: myosin-6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1909 aa)
MYH7LOW QUALITY PROTEIN: myosin-7-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1880 aa)
MYL4Myosin light chain 4 isoform X2. (193 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1. (1049 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
TCAPTelethonin. (167 aa)
TNNI3Troponin I, cardiac muscle isoform X2. (205 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (419 aa)
SGCDDelta-sarcoglycan isoform X1. (289 aa)
TNNI1LOW QUALITY PROTEIN: troponin I, slow skeletal muscle. (185 aa)
SCN4BSodium channel subunit beta-4. (226 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (209 aa)
ABCC9ATP-binding cassette sub-family C member 9 isoform X1. (1549 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (167 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2531 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (188 aa)
CSRP3Cysteine and glycine-rich protein 3. (194 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2127 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (129 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (138 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (218 aa)
KCNH2LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily H member 2. (790 aa)
KCNE4Potassium voltage-gated channel subfamily E member 4. (80 aa)
ENSUMAP00000015803annotation not available (807 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1104 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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