13 items (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SERPINE2	Glia-derived nexin; Belongs to the serpin family. (397 aa)
	GABRA5	Gamma-aminobutyric acid receptor subunit alpha-5 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
	SULF2	Extracellular sulfatase Sulf-2. (803 aa)
	NTF4	LOW QUALITY PROTEIN: neurotrophin-4; Belongs to the NGF-beta family. (210 aa)
	RNF165	RING finger protein 165. (348 aa)
	FBXO45	F-box/SPRY domain-containing protein 1. (262 aa)
	LRIG1	Leucine-rich repeats and immunoglobulin-like domains protein 1. (1026 aa)
	SULF1	Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (886 aa)
	LRIG2	Leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X1. (962 aa)
	CHD7	chromodomain-helicase-DNA-binding protein 7. (2976 aa)
	ECE1	Endothelin-converting enzyme 1. (758 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	EDN1	Endothelin-1. (202 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ECE1	EDN1	ENSUMAP00000020086	ENSUMAP00000024701	Endothelin-converting enzyme 1.	Endothelin-1.	0.948
ECE1	EDNRA	ENSUMAP00000020086	ENSUMAP00000021577	Endothelin-converting enzyme 1.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.601
EDN1	ECE1	ENSUMAP00000024701	ENSUMAP00000020086	Endothelin-1.	Endothelin-converting enzyme 1.	0.948
EDN1	EDNRA	ENSUMAP00000024701	ENSUMAP00000021577	Endothelin-1.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.999
EDNRA	ECE1	ENSUMAP00000021577	ENSUMAP00000020086	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin-converting enzyme 1.	0.601
EDNRA	EDN1	ENSUMAP00000021577	ENSUMAP00000024701	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin-1.	0.999
LRIG1	LRIG2	ENSUMAP00000032981	ENSUMAP00000018294	Leucine-rich repeats and immunoglobulin-like domains protein 1.	Leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X1.	0.447
LRIG2	LRIG1	ENSUMAP00000018294	ENSUMAP00000032981	Leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X1.	Leucine-rich repeats and immunoglobulin-like domains protein 1.	0.447