(11 nodes) Intestinal epithelial cell differentiation network (Ursus maritimus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	YIPF6	Protein YIPF. (236 aa)
	SRC	Tyrosine-protein kinase. (618 aa)
	SAV1	Salvador family WW domain containing protein 1. (351 aa)
	IL6ST	Interleukin-6 receptor subunit beta isoform X1. (918 aa)
	YAP1	LOW QUALITY PROTEIN: yorkie homolog. (457 aa)
	KLF5	Krueppel-like factor 5. (430 aa)
	HIF1A	Hypoxia-inducible factor 1-alpha isoform X2. (823 aa)
	TIGAR	Fructose-2,6-bisphosphatase TIGAR. (211 aa)
	C1GALT1	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (359 aa)
	GATA4	Transcription factor GATA-4. (236 aa)
	ENSUMAP00000030969	annotation not available (251 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GATA4	KLF5	ENSUMAP00000030135	ENSUMAP00000013846	Transcription factor GATA-4.	Krueppel-like factor 5.	0.405
HIF1A	SRC	ENSUMAP00000018657	ENSUMAP00000004515	Hypoxia-inducible factor 1-alpha isoform X2.	Tyrosine-protein kinase.	0.635
KLF5	GATA4	ENSUMAP00000013846	ENSUMAP00000030135	Krueppel-like factor 5.	Transcription factor GATA-4.	0.405
SAV1	YAP1	ENSUMAP00000006921	ENSUMAP00000012521	Salvador family WW domain containing protein 1.	LOW QUALITY PROTEIN: yorkie homolog.	0.820
SRC	HIF1A	ENSUMAP00000004515	ENSUMAP00000018657	Tyrosine-protein kinase.	Hypoxia-inducible factor 1-alpha isoform X2.	0.635
SRC	YAP1	ENSUMAP00000004515	ENSUMAP00000012521	Tyrosine-protein kinase.	LOW QUALITY PROTEIN: yorkie homolog.	0.619
YAP1	SAV1	ENSUMAP00000012521	ENSUMAP00000006921	LOW QUALITY PROTEIN: yorkie homolog.	Salvador family WW domain containing protein 1.	0.820
YAP1	SRC	ENSUMAP00000012521	ENSUMAP00000004515	LOW QUALITY PROTEIN: yorkie homolog.	Tyrosine-protein kinase.	0.619