STRINGSTRING
ZBTB14 ZBTB14 APELA APELA PCSK5 PCSK5 SUFU SUFU ARID2 ARID2 PRICKLE1 PRICKLE1 SPRED1 SPRED1 TAB1 TAB1 LRP2 LRP2 ENSUMAP00000018664 ENSUMAP00000018664 TGFBR1 TGFBR1 GPC3 GPC3 DCTN5 DCTN5 PTK7 PTK7 SRF SRF PDGFRB PDGFRB SETD2 SETD2 SGCD SGCD VEGFB VEGFB SEC24B SEC24B BMP4 BMP4 PLXND1 PLXND1 APLNR APLNR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZBTB14Zinc finger and BTB domain-containing protein 14. (449 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (852 aa)
SUFUSuppressor of fused homolog. (489 aa)
ARID2LOW QUALITY PROTEIN: AT-rich interactive domain-containing protein 2. (1411 aa)
PRICKLE1Prickle-like protein 1. (804 aa)
SPRED1Sprouty-related, EVH1 domain-containing protein 1. (445 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (498 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (403 aa)
ENSUMAP00000018664annotation not available (401 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (625 aa)
DCTN5Dynactin subunit 5. (222 aa)
PTK7Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1081 aa)
SRFSerum response factor. (446 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1152 aa)
SETD2Histone-lysine N-methyltransferase SETD2. (2520 aa)
SGCDDelta-sarcoglycan isoform X1. (289 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (167 aa)
SEC24BProtein transport protein Sec24B. (1144 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
PLXND1LOW QUALITY PROTEIN: plexin-D1. (1503 aa)
APLNRApelin receptor. (330 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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