(20 nodes) Positive regulation of cartilage development network (Ursus maritimus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	MUSTN1	Musculoskeletal embryonic nuclear protein 1. (82 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	GDF2	Growth/differentiation factor 2. (402 aa)
	SMAD3	Mothers against decapentaplegic homolog. (280 aa)
	PKDCC	Protein kinase domain-containing protein, cytoplasmic. (291 aa)
	SOX6	Transcription factor SOX-6 isoform X2. (855 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
	ENSUMAP00000001989	annotation not available (146 aa)
	CCN1	Cellular communication network factor 1. (382 aa)
	LOC103665211	Mothers against decapentaplegic homolog. (244 aa)
	ENSUMAP00000003766	annotation not available (297 aa)
	ZBTB16	Zinc finger and BTB domain-containing protein 16. (673 aa)
	BMPR1B	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
	LOXL2	Lysyl oxidase homolog 2 isoform X3. (829 aa)
	GDF5	LOW QUALITY PROTEIN: growth/differentiation factor 5. (306 aa)
	BMP2	Bone morphogenetic protein 2 isoform X2. (395 aa)
	BMP1	Metalloendopeptidase. (1005 aa)
	GLI3	Transcriptional activator GLI3. (524 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP1	BMP2	ENSUMAP00000008178	ENSUMAP00000006638	Metalloendopeptidase.	Bone morphogenetic protein 2 isoform X2.	0.418
BMP1	BMP4	ENSUMAP00000008178	ENSUMAP00000021648	Metalloendopeptidase.	Bone morphogenetic protein 4.	0.511
BMP1	LOXL2	ENSUMAP00000008178	ENSUMAP00000006012	Metalloendopeptidase.	Lysyl oxidase homolog 2 isoform X3.	0.430
BMP10	BMP4	ENSUMAP00000029171	ENSUMAP00000021648	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.551
BMP10	BMPR1B	ENSUMAP00000029171	ENSUMAP00000005818	Bone morphogenetic protein 10.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.547
BMP10	GDF2	ENSUMAP00000029171	ENSUMAP00000021194	Bone morphogenetic protein 10.	Growth/differentiation factor 2.	0.832
BMP10	SMAD3	ENSUMAP00000029171	ENSUMAP00000016415	Bone morphogenetic protein 10.	Mothers against decapentaplegic homolog.	0.659
BMP2	BMP1	ENSUMAP00000006638	ENSUMAP00000008178	Bone morphogenetic protein 2 isoform X2.	Metalloendopeptidase.	0.418
BMP2	BMP4	ENSUMAP00000006638	ENSUMAP00000021648	Bone morphogenetic protein 2 isoform X2.	Bone morphogenetic protein 4.	0.928
BMP2	BMPR1B	ENSUMAP00000006638	ENSUMAP00000005818	Bone morphogenetic protein 2 isoform X2.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.991
BMP2	FGF18	ENSUMAP00000006638	ENSUMAP00000034256	Bone morphogenetic protein 2 isoform X2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.644
BMP2	GDF5	ENSUMAP00000006638	ENSUMAP00000006468	Bone morphogenetic protein 2 isoform X2.	LOW QUALITY PROTEIN: growth/differentiation factor 5.	0.495
BMP2	LOC103665211	ENSUMAP00000006638	ENSUMAP00000003199	Bone morphogenetic protein 2 isoform X2.	Mothers against decapentaplegic homolog.	0.700
BMP2	SMAD1	ENSUMAP00000006638	ENSUMAP00000021317	Bone morphogenetic protein 2 isoform X2.	Mothers against decapentaplegic homolog.	0.801
BMP2	SMAD3	ENSUMAP00000006638	ENSUMAP00000016415	Bone morphogenetic protein 2 isoform X2.	Mothers against decapentaplegic homolog.	0.584
BMP4	BMP1	ENSUMAP00000021648	ENSUMAP00000008178	Bone morphogenetic protein 4.	Metalloendopeptidase.	0.511
BMP4	BMP10	ENSUMAP00000021648	ENSUMAP00000029171	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.551
BMP4	BMP2	ENSUMAP00000021648	ENSUMAP00000006638	Bone morphogenetic protein 4.	Bone morphogenetic protein 2 isoform X2.	0.928
BMP4	BMPR1B	ENSUMAP00000021648	ENSUMAP00000005818	Bone morphogenetic protein 4.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.996
BMP4	FGF18	ENSUMAP00000021648	ENSUMAP00000034256	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.653