(10 nodes) Dopamine uptake network (Ursus maritimus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC22A3	Solute carrier family 22 member 3 isoform X2. (404 aa)
	SLC22A2	LOW QUALITY PROTEIN: solute carrier family 22 member 2. (514 aa)
	SLC22A1	LOW QUALITY PROTEIN: solute carrier family 22 member 1. (549 aa)
	ENSUMAP00000027960	annotation not available (155 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
	PARK7	Parkinsonism associated deglycase. (189 aa)
	SLC6A2	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (629 aa)
	PARK2	E3 ubiquitin-protein ligase parkin isoform X5. (153 aa)
	ENSUMAP00000015922	annotation not available (110 aa)
	PARK2-2	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (176 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSUMAP00000015922	ENSUMAP00000027960	ENSUMAP00000015922	ENSUMAP00000027960	annotation not available	annotation not available	0.704
ENSUMAP00000015922	PARK2	ENSUMAP00000015922	ENSUMAP00000015895	annotation not available	E3 ubiquitin-protein ligase parkin isoform X5.	0.900
ENSUMAP00000015922	PARK2-2	ENSUMAP00000015922	ENSUMAP00000015959	annotation not available	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.928
ENSUMAP00000015922	PARK7	ENSUMAP00000015922	ENSUMAP00000033471	annotation not available	Parkinsonism associated deglycase.	0.704
ENSUMAP00000027960	ENSUMAP00000015922	ENSUMAP00000027960	ENSUMAP00000015922	annotation not available	annotation not available	0.704
ENSUMAP00000027960	PARK2	ENSUMAP00000027960	ENSUMAP00000015895	annotation not available	E3 ubiquitin-protein ligase parkin isoform X5.	0.638
ENSUMAP00000027960	PARK2-2	ENSUMAP00000027960	ENSUMAP00000015959	annotation not available	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.704
PARK2	ENSUMAP00000015922	ENSUMAP00000015895	ENSUMAP00000015922	E3 ubiquitin-protein ligase parkin isoform X5.	annotation not available	0.900
PARK2	ENSUMAP00000027960	ENSUMAP00000015895	ENSUMAP00000027960	E3 ubiquitin-protein ligase parkin isoform X5.	annotation not available	0.638
PARK2	PARK2-2	ENSUMAP00000015895	ENSUMAP00000015959	E3 ubiquitin-protein ligase parkin isoform X5.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.900
PARK2	PARK7	ENSUMAP00000015895	ENSUMAP00000033471	E3 ubiquitin-protein ligase parkin isoform X5.	Parkinsonism associated deglycase.	0.638
PARK2-2	ENSUMAP00000015922	ENSUMAP00000015959	ENSUMAP00000015922	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	annotation not available	0.928
PARK2-2	ENSUMAP00000027960	ENSUMAP00000015959	ENSUMAP00000027960	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	annotation not available	0.704
PARK2-2	PARK2	ENSUMAP00000015959	ENSUMAP00000015895	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	E3 ubiquitin-protein ligase parkin isoform X5.	0.900
PARK2-2	PARK7	ENSUMAP00000015959	ENSUMAP00000033471	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	Parkinsonism associated deglycase.	0.704
PARK7	ENSUMAP00000015922	ENSUMAP00000033471	ENSUMAP00000015922	Parkinsonism associated deglycase.	annotation not available	0.704
PARK7	PARK2	ENSUMAP00000033471	ENSUMAP00000015895	Parkinsonism associated deglycase.	E3 ubiquitin-protein ligase parkin isoform X5.	0.638
PARK7	PARK2-2	ENSUMAP00000033471	ENSUMAP00000015959	Parkinsonism associated deglycase.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.704
SLC22A2	SLC22A3	ENSUMAP00000016071	ENSUMAP00000016060	LOW QUALITY PROTEIN: solute carrier family 22 member 2.	Solute carrier family 22 member 3 isoform X2.	0.905
SLC22A3	SLC22A2	ENSUMAP00000016060	ENSUMAP00000016071	Solute carrier family 22 member 3 isoform X2.	LOW QUALITY PROTEIN: solute carrier family 22 member 2.	0.905