16 items (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LGMN	Legumain. (433 aa)
	CYCS	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	CYFIP2	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1056 aa)
	BAD	Bcl2-associated agonist of cell death. (168 aa)
	NLRP6	NACHT, LRR and PYD domains-containing protein 6. (795 aa)
	FADD	FAS-associated death domain protein. (192 aa)
	ENSUMAP00000010849	annotation not available (93 aa)
	LOC103665481	Putative Bcl-2 homologous antagonist/killer 2. (349 aa)
	ASPH	Aspartyl/asparaginyl beta-hydroxylase isoform X2. (756 aa)
	PYCARD	Apoptosis-associated speck-like protein containing a CARD isoform X1. (194 aa)
	RIPK2	LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 2. (512 aa)
	TBC1D10A	TBC1 domain family member 10A. (518 aa)
	CASP10	Caspase-10 isoform X1; Belongs to the peptidase C14A family. (481 aa)
	CASP8	Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa)
	CASP9	Caspase-9 isoform X1; Belongs to the peptidase C14A family. (413 aa)
	CIDEB	Cell death inducing DFFA like effector b. (221 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAD	CASP9	ENSUMAP00000003173	ENSUMAP00000030022	Bcl2-associated agonist of cell death.	Caspase-9 isoform X1; Belongs to the peptidase C14A family.	0.623
BAD	FADD	ENSUMAP00000003173	ENSUMAP00000009429	Bcl2-associated agonist of cell death.	FAS-associated death domain protein.	0.505
BAD	LOC103665481	ENSUMAP00000003173	ENSUMAP00000016562	Bcl2-associated agonist of cell death.	Putative Bcl-2 homologous antagonist/killer 2.	0.848
CASP10	CASP8	ENSUMAP00000029779	ENSUMAP00000029788	Caspase-10 isoform X1; Belongs to the peptidase C14A family.	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	0.977
CASP10	CASP9	ENSUMAP00000029779	ENSUMAP00000030022	Caspase-10 isoform X1; Belongs to the peptidase C14A family.	Caspase-9 isoform X1; Belongs to the peptidase C14A family.	0.716
CASP10	CYCS	ENSUMAP00000029779	ENSUMAP00000001665	Caspase-10 isoform X1; Belongs to the peptidase C14A family.	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.686
CASP10	FADD	ENSUMAP00000029779	ENSUMAP00000009429	Caspase-10 isoform X1; Belongs to the peptidase C14A family.	FAS-associated death domain protein.	0.996
CASP10	PYCARD	ENSUMAP00000029779	ENSUMAP00000019312	Caspase-10 isoform X1; Belongs to the peptidase C14A family.	Apoptosis-associated speck-like protein containing a CARD isoform X1.	0.647
CASP10	RIPK2	ENSUMAP00000029779	ENSUMAP00000020907	Caspase-10 isoform X1; Belongs to the peptidase C14A family.	LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 2.	0.451
CASP8	CASP10	ENSUMAP00000029788	ENSUMAP00000029779	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	Caspase-10 isoform X1; Belongs to the peptidase C14A family.	0.977
CASP8	CASP9	ENSUMAP00000029788	ENSUMAP00000030022	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	Caspase-9 isoform X1; Belongs to the peptidase C14A family.	0.722
CASP8	CYCS	ENSUMAP00000029788	ENSUMAP00000001665	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.817
CASP8	FADD	ENSUMAP00000029788	ENSUMAP00000009429	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	FAS-associated death domain protein.	0.999
CASP8	LOC103665481	ENSUMAP00000029788	ENSUMAP00000016562	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	Putative Bcl-2 homologous antagonist/killer 2.	0.594
CASP8	PYCARD	ENSUMAP00000029788	ENSUMAP00000019312	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	Apoptosis-associated speck-like protein containing a CARD isoform X1.	0.973
CASP8	RIPK2	ENSUMAP00000029788	ENSUMAP00000020907	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	LOW QUALITY PROTEIN: receptor-interacting serine/threonine-protein kinase 2.	0.477
CASP9	BAD	ENSUMAP00000030022	ENSUMAP00000003173	Caspase-9 isoform X1; Belongs to the peptidase C14A family.	Bcl2-associated agonist of cell death.	0.623
CASP9	CASP10	ENSUMAP00000030022	ENSUMAP00000029779	Caspase-9 isoform X1; Belongs to the peptidase C14A family.	Caspase-10 isoform X1; Belongs to the peptidase C14A family.	0.716
CASP9	CASP8	ENSUMAP00000030022	ENSUMAP00000029788	Caspase-9 isoform X1; Belongs to the peptidase C14A family.	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	0.722
CASP9	CYCS	ENSUMAP00000030022	ENSUMAP00000001665	Caspase-9 isoform X1; Belongs to the peptidase C14A family.	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.999