STRINGSTRING
NR4A2 NR4A2 PML PML AGT AGT FLCN FLCN PMAIP1 PMAIP1 CCAR2 CCAR2 NANOS3 NANOS3 CX3CR1 CX3CR1 BMPR1B BMPR1B TRIM32 TRIM32 TMEM14A TMEM14A TRAF1 TRAF1 GFRAL GFRAL CD74 CD74 TP63 TP63 SRC SRC DAB2IP DAB2IP ENSUMAP00000004324 ENSUMAP00000004324 OPA1 OPA1 PAK2 PAK2 CRADD CRADD DNM1L DNM1L ENSUMAP00000003507 ENSUMAP00000003507 BCL2 BCL2 NOC2L NOC2L BDKRB2 BDKRB2 ACAA2 ACAA2 BAD BAD DEDD2 DEDD2 BCL2L12 BCL2L12 BCL10 BCL10 BCL2L14 BCL2L14 CAV1 CAV1 SLC25A5 SLC25A5 ENSUMAP00000002305 ENSUMAP00000002305 PIH1D1 PIH1D1 HTRA2 HTRA2 CDK11B CDK11B ADORA2A ADORA2A GSDME GSDME BAX BAX TPD52L1 TPD52L1 RBCK1 RBCK1 BCL2L1 BCL2L1 TNFRSF12A TNFRSF12A HERPUD1 HERPUD1 PEA15 PEA15 HYOU1 HYOU1 ENSUMAP00000000459 ENSUMAP00000000459 CLU CLU PLAGL2 PLAGL2 SERINC3 SERINC3 FOSL1 FOSL1 IL19 IL19 GSK3B GSK3B ENSUMAP00000035005 ENSUMAP00000035005 EYA2 EYA2 CDKN2D CDKN2D PSME3 PSME3 BECN1 BECN1 MAPK9 MAPK9 SELENOS SELENOS SNAI1 SNAI1 PTPN1 PTPN1 EYA4 EYA4 PRELID1 PRELID1 LRRK2 LRRK2 PARK7 PARK7 BCLAF1 BCLAF1 IL20RA IL20RA TNFAIP3 TNFAIP3 MEIS3 MEIS3 ITPRIP ITPRIP DDIAS DDIAS QARS1 QARS1 TRAF2 TRAF2 PLAUR PLAUR NFATC4 NFATC4 WFS1 WFS1 RIPK3 RIPK3 ENSUMAP00000031695 ENSUMAP00000031695 SLC25A31 SLC25A31 TXNDC12 TXNDC12 RPS6KB1 RPS6KB1 TRAF7 TRAF7 AATF AATF SLC35F6 SLC35F6 IVNS1ABP IVNS1ABP FAM167A FAM167A ENSUMAP00000030073 ENSUMAP00000030073 STRADB STRADB CFLAR CFLAR DEPTOR DEPTOR G0S2 G0S2 ING2 ING2 BCAP31 BCAP31 NCK2 NCK2 MDM2 MDM2 S100A9 S100A9 S100A8 S100A8 FXN FXN SH3RF1 SH3RF1 ENSUMAP00000027960 ENSUMAP00000027960 DDIT3 DDIT3 LOC103658125 LOC103658125 LOC103658124 LOC103658124 LOC103658131 LOC103658131 TRIM61 TRIM61 CLUL1 CLUL1 TMBIM1 TMBIM1 MUC1 MUC1 ENSUMAP00000026814 ENSUMAP00000026814 RNF183 RNF183 BIRC6 BIRC6 IGF1 IGF1 LOC103658794 LOC103658794 SLC25A6 SLC25A6 TRIM39-RPP21 TRIM39-RPP21 PINK1 PINK1 ENSUMAP00000025747 ENSUMAP00000025747 EYA1 EYA1 RIPK1 RIPK1 ZSWIM2 ZSWIM2 ITGAV ITGAV ARHGEF2 ARHGEF2 LMNA LMNA EEF1E1 EEF1E1 ATF3 ATF3 CD44 CD44 SCG2 SCG2 RRM2B RRM2B RAF1 RAF1 SRPX SRPX ENSUMAP00000023946 ENSUMAP00000023946 AR AR MAPK8IP2 MAPK8IP2 TIMP3 TIMP3 PCGF2 PCGF2 STK3 STK3 HMOX1 HMOX1 TP53 TP53 DDX3X DDX3X NLE1 NLE1 RFFL RFFL PRKRA PRKRA PHIP PHIP NME5 NME5 P4HB P4HB SFRP2 SFRP2 USP47 USP47 FBXW7 FBXW7 TPT1 TPT1 ENSUMAP00000022061 ENSUMAP00000022061 YBX3 YBX3 LGALS3 LGALS3 XBP1 XBP1 BMP4 BMP4 NFE2L2 NFE2L2 ATAD5 ATAD5 ITGA6 ITGA6 TNF TNF NCK1 NCK1 WWOX WWOX NF1 NF1 IL7 IL7 FAIM FAIM PTGER2 PTGER2 ENSUMAP00000019674 ENSUMAP00000019674 THBS1 THBS1 SGK3 SGK3 BCL2L2-PABPN1 BCL2L2-PABPN1 MADD MADD GHITM GHITM PYCARD PYCARD HGF HGF PPIF PPIF INCA1 INCA1 ARMC10 ARMC10 TMC8 TMC8 HIF1A HIF1A BMI1 BMI1 URI1 URI1 ENSUMAP00000018377 ENSUMAP00000018377 KDM1A KDM1A SLC25A4 SLC25A4 STYXL1 STYXL1 ACKR3 ACKR3 HSPB1 HSPB1 TGFBR1 TGFBR1 ENSUMAP00000017171 ENSUMAP00000017171 ENSUMAP00000017147 ENSUMAP00000017147 ENSUMAP00000017050 ENSUMAP00000017050 RAD9A RAD9A FAS FAS NOX1 NOX1 PTEN PTEN SIAH2 SIAH2 TREML1 TREML1 TREM2 TREM2 FBH1 FBH1 LOC103665481 LOC103665481 FEM1B FEM1B CASP2 CASP2 PARK2-2 PARK2-2 ENSUMAP00000015922 ENSUMAP00000015922 LOC103660820 LOC103660820 PARK2 PARK2 BID BID IFI6 IFI6 PELI3 PELI3 EYA3 EYA3 CTSH CTSH NUPR1 NUPR1 RPS3 RPS3 RELA RELA PSMD10 PSMD10 ZNF385A ZNF385A SKIL SKIL BOK BOK ING5 ING5 DDX3Y DDX3Y ENSUMAP00000013924 ENSUMAP00000013924 GCLM GCLM BNIP5 BNIP5 INHBA INHBA ZMYND11 ZMYND11 RACK1 RACK1 PPIA PPIA HTT HTT RB1CC1 RB1CC1 FIGNL1 FIGNL1 YAP1 YAP1 ZC3HC1 ZC3HC1 PTPMT1 PTPMT1 NDUFS3 NDUFS3 PDIA3 PDIA3 ELL3 ELL3 SYVN1 SYVN1 GDNF GDNF EIF2AK3 EIF2AK3 UNC5B UNC5B ENSUMAP00000010835 ENSUMAP00000010835 TNFSF10 TNFSF10 SFPQ SFPQ FAIM2 FAIM2 TMBIM6 TMBIM6 GATA1 GATA1 PTPN2 PTPN2 PAK5 PAK5 PIAS4 PIAS4 LTBR LTBR MARCHF7 MARCHF7 CREB3 CREB3 SIRT1 SIRT1 FADD FADD PPP2R1B PPP2R1B CTTN CTTN FBXW9 FBXW9 RTKN2 RTKN2 CSF2 CSF2 ENSUMAP00000008777 ENSUMAP00000008777 PARL PARL SNAI2 SNAI2 TMEM161A TMEM161A GPER1 GPER1 MAPK7 MAPK7 NDUFA13 NDUFA13 YJEFN3 YJEFN3 FGF10 FGF10 CYLD CYLD CAAP1 CAAP1 RNF34 RNF34 SFRP1 SFRP1 STK4 STK4 PTTG1IP PTTG1IP PTPRC PTPRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NR4A2Nuclear receptor subfamily 4 group A member 2. (605 aa)
PMLPromyelocytic leukemia. (880 aa)
AGTAngiotensinogen; Belongs to the serpin family. (475 aa)
FLCNFolliculin. (579 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (53 aa)
CCAR2Cell cycle and apoptosis regulator protein 2 isoform X1. (918 aa)
NANOS3Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (179 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (654 aa)
TMEM14ATransmembrane protein 14A isoform X1. (99 aa)
TRAF1TNF receptor-associated factor. (408 aa)
GFRALGDNF family receptor alpha-like. (373 aa)
CD74LOW QUALITY PROTEIN: HLA class II histocompatibility antigen gamma chain. (279 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
SRCTyrosine-protein kinase. (618 aa)
DAB2IPDisabled homolog 2-interacting protein. (877 aa)
ENSUMAP00000004324annotation not available (106 aa)
OPA1Dynamin-like 120 kDa protein, mitochondrial; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (997 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (250 aa)
DNM1LDynamin-1-like protein isoform X7; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
ENSUMAP00000003507annotation not available (155 aa)
BCL2Apoptosis regulator Bcl-2. (177 aa)
NOC2LNucleolar complex protein 2 homolog. (908 aa)
BDKRB2B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (392 aa)
ACAA23-ketoacyl-CoA thiolase, mitochondrial isoform X1; Belongs to the thiolase-like superfamily. Thiolase family. (485 aa)
BADBcl2-associated agonist of cell death. (168 aa)
DEDD2DNA-binding death effector domain-containing protein 2. (327 aa)
BCL2L12Bcl-2-like protein 12. (255 aa)
BCL10BCL10 immune signaling adaptor. (234 aa)
BCL2L14Apoptosis facilitator Bcl-2-like protein 14 isoform X1. (341 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SLC25A5ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (282 aa)
ENSUMAP00000002305annotation not available (122 aa)
PIH1D1PIH1 domain-containing protein 1. (402 aa)
HTRA2LOW QUALITY PROTEIN: serine protease HTRA2, mitochondrial. (455 aa)
CDK11BCyclin-dependent kinase 11B isoform X1. (866 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
GSDMENon-syndromic hearing impairment protein 5. (495 aa)
BAXApoptosis regulator BAX. (221 aa)
TPD52L1Tumor protein D53 isoform X2. (191 aa)
RBCK1ranBP-type and C3HC4-type zinc finger-containing protein 1. (521 aa)
BCL2L1Bcl-2-like protein 1 isoform X1. (233 aa)
TNFRSF12ATumor necrosis factor receptor superfamily member 12A. (160 aa)
HERPUD1Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein. (381 aa)
PEA15Astrocytic phosphoprotein PEA-15. (130 aa)
HYOU1Hypoxia up-regulated protein 1 isoform X2. (996 aa)
ENSUMAP00000000459annotation not available (218 aa)
CLUClusterin; Belongs to the clusterin family. (476 aa)
PLAGL2Zinc finger protein PLAGL2. (496 aa)
SERINC3Serine incorporator 3. (473 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
IL19Interleukin-19. (177 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
ENSUMAP00000035005annotation not available (128 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (509 aa)
CDKN2DCyclin-dependent kinase 4 inhibitor D. (147 aa)
PSME3Proteasome activator complex subunit 3. (254 aa)
BECN1Beclin-1 isoform X1. (555 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
SELENOSSelenoprotein S. (183 aa)
SNAI1Zinc finger protein SNAI1. (246 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (424 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (616 aa)
PRELID1PRELI domain-containing protein 1, mitochondrial. (219 aa)
LRRK2LOW QUALITY PROTEIN: leucine-rich repeat serine/threonine-protein kinase 2. (2513 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
BCLAF1Bcl-2-associated transcription factor 1 isoform X1. (921 aa)
IL20RAInterleukin-20 receptor subunit alpha. (502 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (714 aa)
MEIS3Homeobox protein Meis3. (350 aa)
ITPRIPLOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor-interacting protein. (470 aa)
DDIASNitric oxide-inducible gene protein. (898 aa)
QARS1LOW QUALITY PROTEIN: glutamine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (782 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (494 aa)
PLAURUrokinase plasminogen activator surface receptor. (335 aa)
NFATC4LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 4. (787 aa)
WFS1LOW QUALITY PROTEIN: wolframin. (853 aa)
RIPK3Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily. (487 aa)
ENSUMAP00000031695annotation not available (241 aa)
SLC25A31ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (316 aa)
TXNDC12Thioredoxin domain-containing protein 12 isoform X1. (172 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
TRAF7E3 ubiquitin-protein ligase TRAF7. (102 aa)
AATFProtein AATF. (523 aa)
SLC35F6Solute carrier family 35 member F6; May play a role as a nucleotide-sugar transporter. (358 aa)
IVNS1ABPInfluenza virus NS1A-binding protein. (642 aa)
FAM167AProtein FAM167A. (196 aa)
ENSUMAP00000030073annotation not available (98 aa)
STRADBSTE20-related kinase adapter protein beta. (329 aa)
CFLARCASP8 and FADD-like apoptosis regulator isoform X2; Belongs to the peptidase C14A family. (482 aa)
DEPTORDEP domain-containing mTOR-interacting protein. (394 aa)
G0S2G0/G1 switch protein 2. (106 aa)
ING2Inhibitor of growth protein. (174 aa)
BCAP31B-cell receptor-associated protein 31. (246 aa)
NCK2Cytoplasmic protein. (380 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
S100A9Protein S100; Belongs to the S-100 family. (130 aa)
S100A8Protein S100; Belongs to the S-100 family. (136 aa)
FXNFrataxin, mitochondrial. (135 aa)
SH3RF1E3 ubiquitin-protein ligase SH3RF1. (869 aa)
ENSUMAP00000027960annotation not available (155 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
LOC103658125Putative tripartite motif-containing protein 75. (309 aa)
LOC103658124Tripartite motif-containing protein 60-like. (200 aa)
LOC103658131Putative tripartite motif-containing protein 75. (105 aa)
TRIM61Tripartite motif-containing protein 60-like. (216 aa)
CLUL1Clusterin; Belongs to the clusterin family. (464 aa)
TMBIM1Transmembrane BAX inhibitor motif containing 1; Belongs to the BI1 family. (311 aa)
MUC1Mucin-1. (477 aa)
ENSUMAP00000026814annotation not available (119 aa)
RNF183RING finger protein 183. (190 aa)
BIRC6Baculoviral IAP repeat-containing protein 6. (4808 aa)
IGF1Insulin-like growth factor I isoform X1. (184 aa)
LOC103658794Protein lifeguard 2-like; Belongs to the BI1 family. (285 aa)
SLC25A6ADP/ATP translocase 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (292 aa)
TRIM39-RPP21E3 ubiquitin-protein ligase TRIM39 isoform X2. (469 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (533 aa)
ENSUMAP00000025747annotation not available (76 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (515 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (665 aa)
ZSWIM2E3 ubiquitin-protein ligase ZSWIM2. (633 aa)
ITGAVLOW QUALITY PROTEIN: integrin alpha-V; Belongs to the integrin alpha chain family. (1056 aa)
ARHGEF2Rho guanine nucleotide exchange factor 2. (725 aa)
LMNALamin A/C. (576 aa)
EEF1E1Eukaryotic translation elongation factor 1 epsilon-1 isoform X1. (174 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3. (181 aa)
CD44CD44 antigen isoform X7. (581 aa)
SCG2Secretogranin-2. (578 aa)
RRM2BLOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase subunit M2 B. (351 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
SRPXSushi repeat containing protein X-linked. (463 aa)
ENSUMAP00000023946annotation not available (124 aa)
ARAndrogen receptor. (709 aa)
MAPK8IP2C-Jun-amino-terminal kinase-interacting protein 2. (559 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)
PCGF2Polycomb group RING finger protein 2 isoform X1. (326 aa)
STK3Serine/threonine-protein kinase 3. (497 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (264 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
DDX3XDEAD-box helicase 3 X-linked. (608 aa)
NLE1Notchless protein homolog 1 isoform X1. (442 aa)
RFFLRing finger and FYVE like domain containing E3 ubiquitin protein ligase. (392 aa)
PRKRAInterferon-inducible double-stranded RNA-dependent protein kinase activator A. (288 aa)
PHIPPH-interacting protein. (1759 aa)
NME5Nucleoside diphosphate kinase homolog 5 isoform X1; Belongs to the NDK family. (211 aa)
P4HBLOW QUALITY PROTEIN: protein disulfide-isomerase. (474 aa)
SFRP2Secreted frizzled-related protein 2. (299 aa)
USP47Ubiquitin carboxyl-terminal hydrolase 47; Belongs to the peptidase C19 family. (1349 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform X1. (706 aa)
TPT1Translationally-controlled tumor protein; Belongs to the TCTP family. (145 aa)
ENSUMAP00000022061annotation not available (81 aa)
YBX3Y-box-binding protein 3. (302 aa)
LGALS3Galectin. (282 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (211 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform X2. (590 aa)
ATAD5ATPase family AAA domain-containing protein 5. (1847 aa)
ITGA6LOW QUALITY PROTEIN: integrin alpha-6; Belongs to the integrin alpha chain family. (1051 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
NCK1NCK adaptor protein 1. (244 aa)
WWOXWW domain-containing oxidoreductase. (377 aa)
NF1Neurofibromin. (2862 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (158 aa)
FAIMFas apoptotic inhibitory molecule 1. (201 aa)
PTGER2Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (408 aa)
ENSUMAP00000019674annotation not available (104 aa)
THBS1LOW QUALITY PROTEIN: thrombospondin-1. (1168 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa)
BCL2L2-PABPN1Polyadenylate-binding protein 2. (333 aa)
MADDMAP kinase-activating death domain protein isoform X1. (1650 aa)
GHITMGrowth hormone-inducible transmembrane protein; Belongs to the BI1 family. (345 aa)
PYCARDApoptosis-associated speck-like protein containing a CARD isoform X1. (194 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
PPIFPeptidyl-prolyl isomerase F (cyclophilin D). (105 aa)
INCA1LOW QUALITY PROTEIN: protein INCA1. (227 aa)
ARMC10Armadillo repeat-containing protein 10. (316 aa)
TMC8Transmembrane channel-like protein. (707 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X2. (823 aa)
BMI1Polycomb complex protein BMI-1. (326 aa)
URI1Unconventional prefoldin RPB5 interactor 1. (457 aa)
ENSUMAP00000018377annotation not available (92 aa)
KDM1ALysine-specific histone demethylase 1A isoform X2. (671 aa)
SLC25A4ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (288 aa)
STYXL1Serine/threonine/tyrosine-interacting-like protein 1. (316 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (290 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
ENSUMAP00000017171annotation not available (131 aa)
ENSUMAP00000017147annotation not available (109 aa)
ENSUMAP00000017050annotation not available (80 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (412 aa)
FASTumor necrosis factor receptor superfamily member 6 isoform X1. (351 aa)
NOX1NADPH oxidase 1 isoform X1. (568 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (565 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (315 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (313 aa)
TREM2Triggering receptor expressed on myeloid cells 2 isoform X2. (322 aa)
FBH1F-box only protein 18. (972 aa)
LOC103665481Putative Bcl-2 homologous antagonist/killer 2. (349 aa)
FEM1BProtein fem-1 homolog B. (627 aa)
CASP2Caspase-2 isoform X1; Belongs to the peptidase C14A family. (452 aa)
PARK2-2E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (176 aa)
ENSUMAP00000015922annotation not available (110 aa)
LOC103660820Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (154 aa)
PARK2E3 ubiquitin-protein ligase parkin isoform X5. (153 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa)
IFI6Interferon alpha-inducible protein 6. (259 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa)
EYA3Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (573 aa)
CTSHLOW QUALITY PROTEIN: pro-cathepsin H; Belongs to the peptidase C1 family. (295 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
RPS340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (245 aa)
RELATranscription factor p65. (585 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (297 aa)
ZNF385AZinc finger protein 385A. (244 aa)
SKILSki-like protein isoform X2. (664 aa)
BOKBcl-2-related ovarian killer protein. (300 aa)
ING5Inhibitor of growth protein. (256 aa)
DDX3YLOW QUALITY PROTEIN: ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (704 aa)
ENSUMAP00000013924annotation not available (104 aa)
GCLMGlutamate--cysteine ligase regulatory subunit. (251 aa)
BNIP5Uncharacterized protein C6orf222 homolog. (651 aa)
INHBAInhibin subunit beta A. (424 aa)
ZMYND11Zinc finger MYND domain-containing protein 11 isoform X1. (602 aa)
RACK1Guanine nucleotide-binding protein subunit beta-2-like 1. (374 aa)
PPIAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (170 aa)
HTTLOW QUALITY PROTEIN: huntingtin. (3048 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform X1. (1593 aa)
FIGNL1Fidgetin-like protein 1; Belongs to the AAA ATPase family. (676 aa)
YAP1LOW QUALITY PROTEIN: yorkie homolog. (457 aa)
ZC3HC1Zinc finger C3HC-type containing 1. (502 aa)
PTPMT1Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1. (191 aa)
NDUFS3NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (310 aa)
PDIA3Protein disulfide-isomerase. (458 aa)
ELL3RNA polymerase II elongation factor ELL3. (324 aa)
SYVN1E3 ubiquitin-protein ligase synoviolin. (573 aa)
GDNFGlial cell line-derived neurotrophic factor. (241 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3. (963 aa)
UNC5BNetrin receptor UNC5B. (913 aa)
ENSUMAP00000010835annotation not available (213 aa)
TNFSF10Tumor necrosis factor ligand superfamily member 10; Belongs to the tumor necrosis factor family. (286 aa)
SFPQSplicing factor, proline- and glutamine-rich. (341 aa)
FAIM2Protein lifeguard 2; Belongs to the BI1 family. (319 aa)
TMBIM6LOW QUALITY PROTEIN: bax inhibitor 1; Belongs to the BI1 family. (237 aa)
GATA1LOW QUALITY PROTEIN: erythroid transcription factor. (438 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (400 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
PIAS4E3 SUMO-protein ligase PIAS4. (404 aa)
LTBRTumor necrosis factor receptor superfamily member 3 isoform X2. (421 aa)
MARCHF7E3 ubiquitin-protein ligase MARCH7 isoform X1. (708 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (358 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X2. (446 aa)
FADDFAS-associated death domain protein. (192 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (650 aa)
CTTNSrc substrate cortactin. (512 aa)
FBXW9F-box/WD repeat-containing protein 9. (367 aa)
RTKN2Rhotekin-2. (294 aa)
CSF2Granulocyte-macrophage colony-stimulating factor isoform X1. (277 aa)
ENSUMAP00000008777annotation not available (79 aa)
PARLPresenilins-associated rhomboid-like protein, mitochondrial. (381 aa)
SNAI2Zinc finger protein SNAI2. (263 aa)
TMEM161ATransmembrane protein 161A. (299 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (264 aa)
NDUFA13NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (161 aa)
YJEFN3yjeF N-terminal domain-containing protein 3. (142 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
CYLDLOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (948 aa)
CAAP1Caspase activity and apoptosis inhibitor 1. (359 aa)
RNF34E3 ubiquitin-protein ligase RNF34 isoform X1. (376 aa)
SFRP1Secreted frizzled-related protein 1. (305 aa)
STK4Serine/threonine-protein kinase 4. (496 aa)
PTTG1IPPituitary tumor-transforming gene 1 protein-interacting protein. (259 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1268 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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