(12 nodes) Small GTPase Rho network (Ursus maritimus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAC2	Ras-related C3 botulinum toxin substrate 2. (231 aa)
	RND2	Rho-related GTP-binding protein RhoN. (207 aa)
	RHOA	Ras homolog family member A. (193 aa)
	LOC103682585	Rho-related GTP-binding protein RhoG-like. (250 aa)
	RND3	Rho-related GTP-binding protein RhoE. (244 aa)
	RHOC	Rho-related GTP-binding protein RhoC. (193 aa)
	RHOT1	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (662 aa)
	CDC42	Cell division control protein 42 homolog isoform X1. (191 aa)
	RHOJ	Rho-related GTP-binding protein RhoJ isoform X1. (236 aa)
	RHOBTB1	LOW QUALITY PROTEIN: rho-related BTB domain-containing protein 1. (682 aa)
	RND1	Rho-related GTP-binding protein Rho6. (232 aa)
	RHOBTB2	Rho-related BTB domain-containing protein 2. (728 aa)

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	LOC103682585	ENSUMAP00000018621	ENSUMAP00000029713	Cell division control protein 42 homolog isoform X1.	Rho-related GTP-binding protein RhoG-like.	0.426
CDC42	RAC2	ENSUMAP00000018621	ENSUMAP00000021404	Cell division control protein 42 homolog isoform X1.	Ras-related C3 botulinum toxin substrate 2.	0.551
CDC42	RHOA	ENSUMAP00000018621	ENSUMAP00000031637	Cell division control protein 42 homolog isoform X1.	Ras homolog family member A.	0.950
CDC42	RHOC	ENSUMAP00000018621	ENSUMAP00000021421	Cell division control protein 42 homolog isoform X1.	Rho-related GTP-binding protein RhoC.	0.526
CDC42	RND1	ENSUMAP00000018621	ENSUMAP00000008572	Cell division control protein 42 homolog isoform X1.	Rho-related GTP-binding protein Rho6.	0.469
CDC42	RND3	ENSUMAP00000018621	ENSUMAP00000028719	Cell division control protein 42 homolog isoform X1.	Rho-related GTP-binding protein RhoE.	0.461
LOC103682585	CDC42	ENSUMAP00000029713	ENSUMAP00000018621	Rho-related GTP-binding protein RhoG-like.	Cell division control protein 42 homolog isoform X1.	0.426
LOC103682585	RAC2	ENSUMAP00000029713	ENSUMAP00000021404	Rho-related GTP-binding protein RhoG-like.	Ras-related C3 botulinum toxin substrate 2.	0.526
LOC103682585	RHOA	ENSUMAP00000029713	ENSUMAP00000031637	Rho-related GTP-binding protein RhoG-like.	Ras homolog family member A.	0.462
LOC103682585	RHOC	ENSUMAP00000029713	ENSUMAP00000021421	Rho-related GTP-binding protein RhoG-like.	Rho-related GTP-binding protein RhoC.	0.464
LOC103682585	RND1	ENSUMAP00000029713	ENSUMAP00000008572	Rho-related GTP-binding protein RhoG-like.	Rho-related GTP-binding protein Rho6.	0.474
LOC103682585	RND3	ENSUMAP00000029713	ENSUMAP00000028719	Rho-related GTP-binding protein RhoG-like.	Rho-related GTP-binding protein RhoE.	0.468
RAC2	CDC42	ENSUMAP00000021404	ENSUMAP00000018621	Ras-related C3 botulinum toxin substrate 2.	Cell division control protein 42 homolog isoform X1.	0.551
RAC2	LOC103682585	ENSUMAP00000021404	ENSUMAP00000029713	Ras-related C3 botulinum toxin substrate 2.	Rho-related GTP-binding protein RhoG-like.	0.526
RAC2	RHOA	ENSUMAP00000021404	ENSUMAP00000031637	Ras-related C3 botulinum toxin substrate 2.	Ras homolog family member A.	0.493
RAC2	RHOC	ENSUMAP00000021404	ENSUMAP00000021421	Ras-related C3 botulinum toxin substrate 2.	Rho-related GTP-binding protein RhoC.	0.493
RAC2	RND1	ENSUMAP00000021404	ENSUMAP00000008572	Ras-related C3 botulinum toxin substrate 2.	Rho-related GTP-binding protein Rho6.	0.574
RAC2	RND3	ENSUMAP00000021404	ENSUMAP00000028719	Ras-related C3 botulinum toxin substrate 2.	Rho-related GTP-binding protein RhoE.	0.543
RHOA	CDC42	ENSUMAP00000031637	ENSUMAP00000018621	Ras homolog family member A.	Cell division control protein 42 homolog isoform X1.	0.950
RHOA	LOC103682585	ENSUMAP00000031637	ENSUMAP00000029713	Ras homolog family member A.	Rho-related GTP-binding protein RhoG-like.	0.462