STRINGSTRING
CASP3 CASP3 APPL2 APPL2 TMEM198 TMEM198 RIPK1 RIPK1 APPL1 APPL1 FASLG FASLG TRADD TRADD CFLAR CFLAR CASP8 CASP8 CASP9 CASP9 TRAF2 TRAF2 DCC DCC LOC103671065 LOC103671065 FADD FADD DAPK3 DAPK3 TNFSF10 TNFSF10 DAPK1 DAPK1 UNC5B UNC5B FAS FAS DAPK2 DAPK2 CD14 CD14 LOC103682439 LOC103682439
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (619 aa)
TMEM198LOW QUALITY PROTEIN: transmembrane protein 198. (327 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (665 aa)
APPL1DCC-interacting protein 13-alpha. (656 aa)
FASLGTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (269 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (314 aa)
CFLARCASP8 and FADD-like apoptosis regulator isoform X2; Belongs to the peptidase C14A family. (482 aa)
CASP8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa)
CASP9Caspase-9 isoform X1; Belongs to the peptidase C14A family. (413 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (494 aa)
DCCNetrin receptor DCC. (1432 aa)
LOC103671065Uncharacterized protein LOC103671065 isoform X3. (435 aa)
FADDFAS-associated death domain protein. (192 aa)
DAPK3Death-associated protein kinase 3; Belongs to the protein kinase superfamily. (461 aa)
TNFSF10Tumor necrosis factor ligand superfamily member 10; Belongs to the tumor necrosis factor family. (286 aa)
DAPK1Death-associated protein kinase 1 isoform X2. (1415 aa)
UNC5BNetrin receptor UNC5B. (913 aa)
FASTumor necrosis factor receptor superfamily member 6 isoform X1. (351 aa)
DAPK2Death-associated protein kinase 2 isoform X1. (406 aa)
CD14Monocyte differentiation antigen CD14 isoform X2. (439 aa)
LOC103682439Transmembrane protein 198-like isoform X1. (119 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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