STRINGSTRING
UBC UBC RBCK1 RBCK1 TAB2 TAB2 OTUD7B OTUD7B TRAF1 TRAF1 ENSUMAP00000006417 ENSUMAP00000006417 CYLD CYLD ENSUMAP00000008777 ENSUMAP00000008777 ENSUMAP00000009735 ENSUMAP00000009735 TNFRSF1A TNFRSF1A UBA52 UBA52 BIRC2 BIRC2 BIRC3 BIRC3 RACK1 RACK1 MAP3K7 MAP3K7 ENSUMAP00000017050 ENSUMAP00000017050 OPTN OPTN TAB1 TAB1 TAB3 TAB3 TNF TNF RPS27A RPS27A RIPK1 RIPK1 IKBKG IKBKG TRADD TRADD SHARPIN SHARPIN ENSUMAP00000030752 ENSUMAP00000030752 BIRC7 BIRC7 RNF31 RNF31 CHUK CHUK USP4-2 USP4-2 USP4 USP4 TRAF2 TRAF2 USP2 USP2 TNFAIP3 TNFAIP3 USP21 USP21 SPATA2 SPATA2 XIAP XIAP ENSUMAP00000034969 ENSUMAP00000034969 IKBKB IKBKB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBCLOW QUALITY PROTEIN: polyubiquitin-B. (305 aa)
RBCK1ranBP-type and C3HC4-type zinc finger-containing protein 1. (521 aa)
TAB2LOW QUALITY PROTEIN: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (670 aa)
OTUD7BOTU domain-containing protein 7B isoform X1. (844 aa)
TRAF1TNF receptor-associated factor. (408 aa)
ENSUMAP00000006417annotation not available (140 aa)
CYLDLOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (948 aa)
ENSUMAP00000008777annotation not available (79 aa)
ENSUMAP00000009735annotation not available (166 aa)
TNFRSF1ALOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 1A. (507 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (619 aa)
BIRC3Baculoviral IAP repeat-containing protein 3-like. (516 aa)
RACK1Guanine nucleotide-binding protein subunit beta-2-like 1. (374 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ENSUMAP00000017050annotation not available (80 aa)
OPTNLOW QUALITY PROTEIN: optineurin. (490 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (498 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (664 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (184 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (665 aa)
IKBKGNF-kappa-B essential modulator. (291 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (314 aa)
SHARPINSharpin. (414 aa)
ENSUMAP00000030752Polyubiquitin-like. (77 aa)
BIRC7Baculoviral IAP repeat-containing protein 7. (279 aa)
RNF31E3 ubiquitin-protein ligase RNF31 isoform X1. (1080 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (680 aa)
USP4-2Ubiquitin carboxyl-terminal hydrolase 4/11. (459 aa)
USP4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (567 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (494 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (558 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (714 aa)
USP21Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (565 aa)
SPATA2Spermatogenesis-associated protein 2. (453 aa)
XIAPE3 ubiquitin-protein ligase XIAP. (497 aa)
ENSUMAP00000034969annotation not available (120 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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