STRINGSTRING
VCAN VCAN CLDN6 CLDN6 LOC103660614 LOC103660614 CADM3 CADM3 NFASC NFASC CNTN2 CNTN2 CLDN1 CLDN1 CLDN25 CLDN25 SIGLEC1 SIGLEC1 CD226 CD226 CD2 CD2 VTCN1 VTCN1 NECTIN3 NECTIN3 LOC103668088 LOC103668088 CD4 CD4 CD276 CD276 ALCAM ALCAM SELPLG SELPLG LRRC4 LRRC4 ITGA9 ITGA9 JAM3 JAM3 NEGR1 NEGR1 NCAM1 NCAM1 NRXN3 NRXN3 NEO1 NEO1 VCAM1 VCAM1 OCLN OCLN NLGN1 NLGN1 CD8A CD8A CD8B CD8B LOC103672268 LOC103672268 VSIR VSIR LOC103656357 LOC103656357 LRRC4B LRRC4B CD40LG CD40LG PDCD1 PDCD1 CLDN11 CLDN11 CLDN2 CLDN2 LOC103675569 LOC103675569 SPN SPN CD58 CD58 CNTNAP2 CNTNAP2 CD6 CD6 HLA-DOA HLA-DOA HLA-DMA HLA-DMA LOC103665509 LOC103665509 HLA-DOB HLA-DOB LOC103665517 LOC103665517 HLA-DQB1 HLA-DQB1 LOC103665519 LOC103665519 LOC103665521 LOC103665521 HLA-DRA HLA-DRA ITGAL ITGAL CLDN20 CLDN20 NRXN1 NRXN1 CLDN4 CLDN4 GLG1 GLG1 ITGAM ITGAM NCAM2 NCAM2 JAM2 JAM2 CLDN18 CLDN18 ITGA6 ITGA6 ENSUMAP00000021332 ENSUMAP00000021332 LRRC4C LRRC4C ITGB1 ITGB1 MPZL1 MPZL1 CLDN17 CLDN17 CLDN8 CLDN8 SDC2 SDC2 PDCD1LG2 PDCD1LG2 CD274 CD274 ITGA4 ITGA4 ICAM2 ICAM2 SELP SELP SELL SELL SELE SELE PECAM1 PECAM1 CD22 CD22 ITGAV ITGAV PTPRM PTPRM CDH1 CDH1 CDH3 CDH3 CD99 CD99 NLGN4X NLGN4X CDH5 CDH5 LOC103679725 LOC103679725 NLGN3 NLGN3 CDH2 CDH2 CD28 CD28 CTLA4 CTLA4 ITGB8 ITGB8 ICOS ICOS CD34 CD34 PVR PVR SDC1 SDC1 NECTIN2 NECTIN2 F11R F11R CNTN1 CNTN1 PTPRF-2 PTPRF-2 CLDN19 CLDN19 LOC103680441 LOC103680441 CNTNAP1 CNTNAP1 ICAM3 ICAM3 ICAM1 ICAM1 CD40 CD40 CD86 CD86 CLDN10 CLDN10 CD80 CD80 SDC4 SDC4 TIGIT TIGIT PTPRC PTPRC ITGB2 ITGB2 ICOSLG ICOSLG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VCANVersican core protein isoform X2. (2399 aa)
CLDN6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
LOC103660614Endothelial cell-selective adhesion molecule-like. (393 aa)
CADM3Cell adhesion molecule 3. (462 aa)
NFASCNeurofascin isoform X2. (1321 aa)
CNTN2Contactin-2. (1008 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN25Putative claudin-25. (203 aa)
SIGLEC1LOW QUALITY PROTEIN: sialoadhesin. (1692 aa)
CD226CD226 molecule. (336 aa)
CD2T-cell surface antigen CD2. (344 aa)
VTCN1V-set domain-containing T-cell activation inhibitor 1. (275 aa)
NECTIN3Nectin-3. (520 aa)
LOC103668088Claudin-9 isoform X2. (222 aa)
CD4T-cell surface glycoprotein CD4. (460 aa)
CD276CD276 antigen. (318 aa)
ALCAMActivated leukocyte cell adhesion molecule. (583 aa)
SELPLGP-selectin glycoprotein ligand 1. (440 aa)
LRRC4Leucine-rich repeat-containing protein 4. (649 aa)
ITGA9Integrin alpha-9; Belongs to the integrin alpha chain family. (934 aa)
JAM3Junctional adhesion molecule C. (305 aa)
NEGR1Neuronal growth regulator 1. (314 aa)
NCAM1Neural cell adhesion molecule 1. (1077 aa)
NRXN3Neurexin 3 isoform X3. (881 aa)
NEO1Neogenin. (1461 aa)
VCAM1Vascular cell adhesion protein 1 isoform X1. (748 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (489 aa)
NLGN1Neuroligin-1 isoform X1. (608 aa)
CD8AT-cell surface glycoprotein CD8 alpha chain. (239 aa)
CD8BT-cell surface glycoprotein CD8 beta chain. (211 aa)
LOC103672268Class I histocompatibility antigen, Gogo-OKO alpha chain-like; Belongs to the MHC class I family. (351 aa)
VSIRPlatelet receptor Gi24. (252 aa)
LOC103656357H-2 class I histocompatibility antigen, Q10 alpha chain-like; Belongs to the MHC class I family. (418 aa)
LRRC4BLOW QUALITY PROTEIN: leucine-rich repeat-containing protein 4B. (372 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)
PDCD1Programmed cell death protein 1 isoform X1. (288 aa)
CLDN11Claudin-11. (202 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
LOC103675569Glycosylation-dependent cell adhesion molecule 1-like. (158 aa)
SPNLeukosialin. (398 aa)
CD58Lymphocyte function-associated antigen 3. (236 aa)
CNTNAP2Contactin-associated protein-like 2. (275 aa)
CD6T-cell differentiation antigen CD6. (613 aa)
HLA-DOAHLA class II histocompatibility antigen, DO alpha chain; Belongs to the MHC class II family. (246 aa)
HLA-DMAHLA class II histocompatibility antigen, DM alpha chain; Belongs to the MHC class II family. (331 aa)
LOC103665509HLA class II histocompatibility antigen, DM beta chain. (280 aa)
HLA-DOBHLA class II histocompatibility antigen, DO beta chain isoform X1. (297 aa)
LOC103665517DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa)
HLA-DQB1boLa class II histocompatibility antigen, DQB*0101 beta chain-like. (265 aa)
LOC103665519SLA class II histocompatibility antigen, DQ haplotype D alpha chain; Belongs to the MHC class II family. (255 aa)
LOC103665521DLA class II histocompatibility antigen, DR-1 beta chain. (266 aa)
HLA-DRAHLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (254 aa)
ITGALIntegrin alpha-L isoform X1; Belongs to the integrin alpha chain family. (1167 aa)
CLDN20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
NRXN1LOW QUALITY PROTEIN: neurexin-1-beta. (875 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (153 aa)
GLG1Golgi apparatus protein 1. (1059 aa)
ITGAMIntegrin alpha-M isoform X1; Belongs to the integrin alpha chain family. (1157 aa)
NCAM2Neural cell adhesion molecule 2. (833 aa)
JAM2Junctional adhesion molecule 2. (298 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
ITGA6LOW QUALITY PROTEIN: integrin alpha-6; Belongs to the integrin alpha chain family. (1051 aa)
ENSUMAP00000021332Uncharacterized LOC103660472. (219 aa)
LRRC4CLOW QUALITY PROTEIN: leucine-rich repeat-containing protein 4C. (579 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
MPZL1Myelin protein zero-like protein 1. (253 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (186 aa)
PDCD1LG2LOW QUALITY PROTEIN: programmed cell death 1 ligand 2. (236 aa)
CD274Programmed cell death 1 ligand 1. (291 aa)
ITGA4Integrin alpha-4 isoform X2; Belongs to the integrin alpha chain family. (944 aa)
ICAM2Intercellular adhesion molecule 2 isoform X1. (340 aa)
SELPP-selectin isoform X1. (831 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (400 aa)
SELEE-selectin. (607 aa)
PECAM1Platelet endothelial cell adhesion molecule isoform X1. (765 aa)
CD22B-cell receptor CD22 isoform X1. (848 aa)
ITGAVLOW QUALITY PROTEIN: integrin alpha-V; Belongs to the integrin alpha chain family. (1056 aa)
PTPRMReceptor-type tyrosine-protein phosphatase mu. (1390 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (881 aa)
CDH3Cadherin-3; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
CD99CD99 antigen isoform X1. (470 aa)
NLGN4XNeuroligin-4, X-linked. (817 aa)
CDH5LOW QUALITY PROTEIN: cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (720 aa)
LOC103679725Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
NLGN3Neuroligin-3 isoform X1. (843 aa)
CDH2Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (904 aa)
CD28T-cell-specific surface glycoprotein CD28. (277 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (720 aa)
ICOSInducible T-cell costimulator isoform X1. (209 aa)
CD34Hematopoietic progenitor cell antigen CD34. (227 aa)
PVRPoliovirus receptor. (427 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (68 aa)
NECTIN2Nectin-2. (543 aa)
F11RJunctional adhesion molecule A. (298 aa)
CNTN1Contactin-1. (1011 aa)
PTPRF-2Protein tyrosine phosphatase, receptor type F. (283 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
LOC103680441DLA class I histocompatibility antigen, A9/A9 alpha chain-like; Belongs to the MHC class I family. (381 aa)
CNTNAP1Contactin-associated protein 1. (1326 aa)
ICAM3Intercellular adhesion molecule 3. (547 aa)
ICAM1Intercellular adhesion molecule 1. (331 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform X5. (316 aa)
CD86T-lymphocyte activation antigen CD86 isoform X1. (343 aa)
CLDN10Claudin-10. (73 aa)
CD80T-lymphocyte activation antigen CD80. (302 aa)
SDC4Syndecan-4. (255 aa)
TIGITT-cell immunoreceptor with Ig and ITIM domains isoform X1. (245 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1268 aa)
ITGB2Integrin beta. (847 aa)
ICOSLGICOS ligand. (305 aa)
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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