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ND1 | NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (318 aa) | ||||
ND2 | NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa) | ||||
COX1 | Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (514 aa) | ||||
COX2 | Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa) | ||||
ATP8 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (67 aa) | ||||
ATP6 | ATP synthase subunit a. (226 aa) | ||||
COX3 | Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa) | ||||
ND3 | NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (115 aa) | ||||
ND4L | NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (98 aa) | ||||
ND4 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (459 aa) | ||||
ND5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (606 aa) | ||||
ND6 | NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (175 aa) | ||||
CYTB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa) | ||||
IL6 | Interleukin-6. (189 aa) | ||||
RTN3 | Reticulon. (235 aa) | ||||
PSMA7 | Proteasome endopeptidase complex. (256 aa) | ||||
DKK2 | Dickkopf WNT signaling pathway inhibitor 2. (259 aa) | ||||
COX8A | Cytochrome c oxidase subunit 8A, mitochondrial. (69 aa) | ||||
APBB1 | Amyloid beta A4 precursor protein-binding family B member 1 isoform X2. (708 aa) | ||||
COX4I2 | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X1. (171 aa) | ||||
WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa) | ||||
TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (468 aa) | ||||
CSNK2A1 | LOW QUALITY PROTEIN: casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa) | ||||
CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
CALML6 | Calmodulin-like protein 6. (180 aa) | ||||
COX7B2 | Cytochrome c oxidase subunit 7B2, mitochondrial. (81 aa) | ||||
CACNA1S | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1823 aa) | ||||
SLC25A5 | ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (282 aa) | ||||
NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1. (56 aa) | ||||
PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (888 aa) | ||||
LRP6 | Low-density lipoprotein receptor-related protein 6 isoform X1. (1462 aa) | ||||
ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) | ||||
PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) | ||||
GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa) | ||||
BACE1 | Beta-secretase 1 isoform X2; Belongs to the peptidase A1 family. (501 aa) | ||||
IDE | Insulin-degrading enzyme; Belongs to the peptidase M16 family. (1016 aa) | ||||
BAD | Bcl2-associated agonist of cell death. (168 aa) | ||||
ATG2B | Autophagy-related protein 2 homolog B. (2068 aa) | ||||
WNT2 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa) | ||||
PSMB7 | Proteasome subunit beta. (318 aa) | ||||
WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa) | ||||
KRAS | GTPase KRas isoform X3. (189 aa) | ||||
NDUFA12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa) | ||||
ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2714 aa) | ||||
MAPK1 | Mitogen-activated protein kinase. (363 aa) | ||||
ADAM17 | Disintegrin and metalloproteinase domain-containing protein 17. (823 aa) | ||||
APH1A | LOW QUALITY PROTEIN: gamma-secretase subunit APH-1A. (341 aa) | ||||
GRIN2A | Glutamate receptor ionotropic, NMDA 2A. (1412 aa) | ||||
LOC103669231 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (477 aa) | ||||
CTNNB1 | Catenin beta-1. (787 aa) | ||||
SNCA | Alpha-synuclein; Belongs to the synuclein family. (140 aa) | ||||
COX7C | Cytochrome c oxidase subunit 7C, mitochondrial. (63 aa) | ||||
COX5A | Cytochrome c oxidase subunit 5A, mitochondrial. (145 aa) | ||||
PPP3CC | Serine/threonine-protein phosphatase. (525 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (461 aa) | ||||
NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) | ||||
PSMD13 | 26S proteasome non-ATPase regulatory subunit 13. (348 aa) | ||||
LOC103671028 | Cytochrome c oxidase subunit 8B, mitochondrial-like. (70 aa) | ||||
PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) | ||||
LOC103657723 | Tubulin alpha-8 chain. (436 aa) | ||||
CSNK1A1 | Casein kinase I isoform alpha isoform X1; Belongs to the protein kinase superfamily. (380 aa) | ||||
HRAS | GTPase HRas isoform X1. (189 aa) | ||||
NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (116 aa) | ||||
APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1252 aa) | ||||
NDUFS4 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (182 aa) | ||||
ATP5F1D | ATP synthase subunit delta, mitochondrial. (216 aa) | ||||
NDUFS7 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X1; Belongs to the complex I 20 kDa subunit family. (294 aa) | ||||
NDUFB6 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6. (97 aa) | ||||
LOC103681641 | Cytochrome b-c1 complex subunit 10. (62 aa) | ||||
DVL3 | Segment polarity protein dishevelled homolog DVL-3. (423 aa) | ||||
NDUFA13 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (161 aa) | ||||
CALM1 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa) | ||||
WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (334 aa) | ||||
TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) | ||||
GPR83 | Probable G-protein coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (422 aa) | ||||
ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (941 aa) | ||||
FADD | FAS-associated death domain protein. (192 aa) | ||||
GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (360 aa) | ||||
ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (982 aa) | ||||
TNFRSF1A | LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 1A. (507 aa) | ||||
UQCRFS1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa) | ||||
PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1205 aa) | ||||
PSMB2 | Proteasome subunit beta. (261 aa) | ||||
NDUFB5 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform X1. (189 aa) | ||||
TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (416 aa) | ||||
COX4I1 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial. (219 aa) | ||||
WIPI2 | WD repeat domain phosphoinositide-interacting protein 2. (462 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa) | ||||
ATG2A | LOW QUALITY PROTEIN: autophagy-related protein 2 homolog A. (197 aa) | ||||
PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa) | ||||
EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3. (963 aa) | ||||
PSMB1 | Proteasome subunit beta. (241 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (331 aa) | ||||
IL1A | Interleukin-1; Belongs to the IL-1 family. (244 aa) | ||||
ATP5PD | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa) | ||||
PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (310 aa) | ||||
KLC4 | Kinesin light chain 4 isoform X1. (679 aa) | ||||
ATG101 | Autophagy-related protein 101 isoform X2. (218 aa) | ||||
MCU | Calcium uniporter protein, mitochondrial. (300 aa) | ||||
LOC103662441 | Caspase-12-like isoform X1; Belongs to the peptidase C14A family. (493 aa) | ||||
PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) | ||||
NDUFS3 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (310 aa) | ||||
PSMC3 | 26S protease regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (439 aa) | ||||
ATP2A1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1224 aa) | ||||
LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (478 aa) | ||||
RB1CC1 | RB1-inducible coiled-coil protein 1 isoform X1. (1593 aa) | ||||
CAPN1 | Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (740 aa) | ||||
UQCRC2 | Cytochrome b-c1 complex subunit 2, mitochondrial isoform X1; Belongs to the peptidase M16 family. (453 aa) | ||||
PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (561 aa) | ||||
PPP3CB | Serine/threonine-protein phosphatase. (534 aa) | ||||
PSMA2 | Proteasome subunit alpha type. (234 aa) | ||||
NDUFB11 | LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial. (142 aa) | ||||
ATP5MC2 | ATP synthase F(0) complex subunit C2, mitochondrial; Belongs to the ATPase C chain family. (145 aa) | ||||
EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) | ||||
RELA | Transcription factor p65. (585 aa) | ||||
NDUFA11 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11. (141 aa) | ||||
DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (270 aa) | ||||
LOC103668940 | 26S proteasome non-ATPase regulatory subunit 6-like. (186 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (354 aa) | ||||
KLC2 | Kinesin light chain 2. (660 aa) | ||||
PSMA6 | Proteasome subunit alpha type. (246 aa) | ||||
TUBB4A | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (435 aa) | ||||
NDUFA3 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3. (84 aa) | ||||
TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa) | ||||
BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (195 aa) | ||||
NDUFC2 | LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 subunit C2. (97 aa) | ||||
PSMA4 | Proteasome subunit alpha type. (292 aa) | ||||
CACNA1C | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1104 aa) | ||||
LOC103671191 | Cytochrome c oxidase subunit 5B, mitochondrial. (129 aa) | ||||
NRAS | NRAS proto-oncogene, GTPase. (189 aa) | ||||
BECN2 | Beclin-2. (433 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (519 aa) | ||||
WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (107 aa) | ||||
MME | Neprilysin isoform X2. (678 aa) | ||||
CALML4 | Calmodulin-like protein 4 isoform X1. (121 aa) | ||||
TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (461 aa) | ||||
CALML5 | Calmodulin-like protein 5. (149 aa) | ||||
MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
NOX1 | NADPH oxidase 1 isoform X1. (568 aa) | ||||
FAS | Tumor necrosis factor receptor superfamily member 6 isoform X1. (351 aa) | ||||
CHRM3 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (552 aa) | ||||
VDAC2 | Voltage-dependent anion-selective channel protein 2. (566 aa) | ||||
ATP5F1C | ATP synthase subunit gamma. (298 aa) | ||||
SLC25A4 | ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (288 aa) | ||||
NDUFV1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa) | ||||
COX7A2L | Cytochrome c oxidase subunit 7A-related protein, mitochondrial. (114 aa) | ||||
NDUFS8 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial. (205 aa) | ||||
NDUFA2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (107 aa) | ||||
NOS2 | Nitric oxide synthase; Produces nitric oxide (NO). (1096 aa) | ||||
PSMA5 | Proteasome subunit alpha type. (241 aa) | ||||
CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa) | ||||
APH1B | Gamma-secretase subunit APH-1B. (207 aa) | ||||
COX7A2 | LOW QUALITY PROTEIN: uncharacterized protein LOC103657485. (83 aa) | ||||
CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (302 aa) | ||||
PSMC2 | 26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa) | ||||
ATP5PB | ATP synthase F(0) complex subunit B1, mitochondrial. (256 aa) | ||||
WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (299 aa) | ||||
PPIF | Peptidyl-prolyl isomerase F (cyclophilin D). (105 aa) | ||||
PSMB5 | Proteasome subunit beta. (263 aa) | ||||
CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (250 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1375 aa) | ||||
ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (351 aa) | ||||
ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (480 aa) | ||||
PSEN2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa) | ||||
PSMB6 | Proteasome subunit beta. (317 aa) | ||||
COX6A2 | Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa) | ||||
PSMC6 | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa) | ||||
CHRM1 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (418 aa) | ||||
NDUFA7 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. (177 aa) | ||||
ATP5PF | ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (108 aa) | ||||
EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase. (542 aa) | ||||
APP | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] (747 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1067 aa) | ||||
NDUFA9 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial isoform X1. (416 aa) | ||||
NDUFC1 | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial. (76 aa) | ||||
BRAF | Serine/threonine-protein kinase B-raf. (715 aa) | ||||
NDUFB2 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial. (105 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (175 aa) | ||||
PSMD11 | 26S proteasome non-ATPase regulatory subunit 11. (421 aa) | ||||
CDK5R1 | Cyclin-dependent kinase 5 activator 1. (289 aa) | ||||
LOC103667265 | LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (237 aa) | ||||
ATP5MC3 | ATP synthase F(0) complex subunit C3, mitochondrial; Belongs to the ATPase C chain family. (128 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (384 aa) | ||||
ATP5MC1 | ATP synthase F(0) complex subunit C1, mitochondrial isoform X1; Belongs to the ATPase C chain family. (136 aa) | ||||
WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa) | ||||
XBP1 | LOW QUALITY PROTEIN: X-box-binding protein 1. (211 aa) | ||||
KIF5B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (908 aa) | ||||
LOC103663786 | Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (95 aa) | ||||
ATG14 | Beclin 1-associated autophagy-related key regulator. (430 aa) | ||||
CAPN2 | Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (649 aa) | ||||
CDK5 | Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (361 aa) | ||||
LOC103661483 | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa) | ||||
PSMA3 | Proteasome subunit alpha type. (255 aa) | ||||
RTN4 | Reticulon. (978 aa) | ||||
RYR3 | LOW QUALITY PROTEIN: ryanodine receptor 3. (4854 aa) | ||||
UQCR10 | Ubiquinol-cytochrome c reductase, complex III subunit X. (64 aa) | ||||
CHRM5 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (534 aa) | ||||
APC | LOW QUALITY PROTEIN: adenomatous polyposis coli protein. (2824 aa) | ||||
PPID | Peptidyl-prolyl cis-trans isomerase D isoform X2. (370 aa) | ||||
PSMA1 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (355 aa) | ||||
PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (946 aa) | ||||
PSMB3 | Proteasome subunit beta. (258 aa) | ||||
CYBB | Cytochrome b-245 heavy chain. (570 aa) | ||||
PSMC5 | 26S protease regulatory subunit 8 isoform X2; Belongs to the AAA ATPase family. (398 aa) | ||||
COX6C | Cytochrome C oxidase subunit 6C. (75 aa) | ||||
PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (510 aa) | ||||
RAF1 | RAF proto-oncogene serine/threonine-protein kinase. (648 aa) | ||||
ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1. (1029 aa) | ||||
PIK3R4 | Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa) | ||||
ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa) | ||||
VDAC1 | Voltage-dependent anion-selective channel protein 1. (283 aa) | ||||
UQCRQ | Ubiquinol-cytochrome c reductase complex III subunit VII. (82 aa) | ||||
PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (297 aa) | ||||
FZD1 | Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (560 aa) | ||||
PSMD7 | LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 7. (312 aa) | ||||
LOC103675819 | Cytochrome c oxidase subunit 7B, mitochondrial. (80 aa) | ||||
NDUFV2 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial. (249 aa) | ||||
PSMD12 | 26S proteasome non-ATPase regulatory subunit 12. (456 aa) | ||||
TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) | ||||
SLC25A6 | ADP/ATP translocase 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (292 aa) | ||||
HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (294 aa) | ||||
WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (270 aa) | ||||
NDUFA4L2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2. (113 aa) | ||||
PSMC4 | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (472 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (520 aa) | ||||
TUBB | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) | ||||
FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) | ||||
DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) | ||||
WNT5A | Wingless-type MMTV integration site family, member 5. (123 aa) | ||||
KIF5A | Kinesin heavy chain isoform 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1031 aa) | ||||
ATP5PO | ATP synthase subunit O, mitochondrial. (213 aa) | ||||
CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2127 aa) | ||||
LOC103682512 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (165 aa) | ||||
FZD10 | Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (398 aa) | ||||
PSENEN | Presenilin enhancer, gamma-secretase subunit. (101 aa) | ||||
NDUFA6 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Belongs to the complex I LYR family. (147 aa) | ||||
LOC103678327 | Cytochrome c oxidase subunit 6A, mitochondrial. (111 aa) | ||||
PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) | ||||
KIF5C | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (929 aa) | ||||
CYC1 | Cytochrome c1, heme protein, mitochondrial. (266 aa) | ||||
COX7A1 | Cytochrome c oxidase subunit 7A1, mitochondrial. (85 aa) | ||||
NAE1 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (530 aa) | ||||
AXIN1 | Axin-1 isoform X2. (867 aa) | ||||
PPP3R1 | Calcineurin subunit B type 1. (160 aa) | ||||
NDUFS5 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5. (106 aa) | ||||
SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa) | ||||
NDUFS6 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (124 aa) | ||||
NDUFB3 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. (97 aa) | ||||
CASP8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa) | ||||
PSMA8 | Proteasome subunit alpha type. (254 aa) | ||||
NDUFA4 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4. (82 aa) | ||||
CASP9 | Caspase-9 isoform X1; Belongs to the peptidase C14A family. (413 aa) | ||||
FZD7 | LOW QUALITY PROTEIN: frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (541 aa) | ||||
NDUFB10 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10. (165 aa) | ||||
NDUFB9 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Belongs to the complex I LYR family. (234 aa) | ||||
FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) | ||||
NDUFS1 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (727 aa) | ||||
SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (660 aa) | ||||
ENSUMAP00000031254 | Glyceraldehyde-3-phosphate dehydrogenase-like. (197 aa) | ||||
CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha. (680 aa) | ||||
NDUFB8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial. (196 aa) | ||||
ATF6 | Cyclic AMP-dependent transcription factor ATF-6 alpha. (676 aa) | ||||
SLC25A31 | ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (316 aa) | ||||
GNAQ | Guanine nucleotide-binding protein G(Q) subunit alpha. (324 aa) | ||||
TUBB4B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (823 aa) | ||||
CHRFAM7A | CHRNA7-FAM7A fusion protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (540 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2531 aa) | ||||
KLC3 | LOW QUALITY PROTEIN: kinesin light chain 3. (118 aa) | ||||
PSMD6 | 26S proteasome non-ATPase regulatory subunit 6. (439 aa) | ||||
ADAM10 | Disintegrin and metalloproteinase domain-containing protein 10. (674 aa) | ||||
LOC103657024 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1-like. (66 aa) | ||||
SDHC | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial. (169 aa) | ||||
PIK3R3 | LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) | ||||
NDUFS2 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform X2; Belongs to the complex I 49 kDa subunit family. (436 aa) | ||||
ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X3. (2738 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1768 aa) | ||||
FZD4 | Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (534 aa) | ||||
GRM5 | Glutamate metabotropic receptor 5. (959 aa) | ||||
NOX4 | NADPH oxidase 4. (578 aa) | ||||
CASP7 | Caspase-7; Belongs to the peptidase C14A family. (301 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
LOC103680303 | Uncharacterized protein LOC103680303. (101 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase. (514 aa) | ||||
KLC1 | Kinesin light chain 1 isoform X1. (672 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (460 aa) | ||||
BECN1 | Beclin-1 isoform X1. (555 aa) | ||||
NDUFB4 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. (129 aa) | ||||
GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) | ||||
NDUFV3 | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial. (469 aa) | ||||
VDAC3 | Voltage-dependent anion-selective channel protein 3. (283 aa) | ||||
DKK4 | Dickkopf WNT signaling pathway inhibitor 4. (221 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa) |