(12 nodes) Dwarfin, and c-SKI Smad4 binding domain network (Neomonachus schauinslandi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMURF2	E3 ubiquitin-protein ligase. (736 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	SMAD9	Mothers against decapentaplegic homolog. (469 aa)
	SMURF1	E3 ubiquitin-protein ligase. (731 aa)
	SKI	Ski oncogene isoform X1. (731 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	SMAD7	Mothers against decapentaplegic homolog. (426 aa)
	LOC110583310	Mothers against decapentaplegic homolog. (451 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	SMAD6	Mothers against decapentaplegic homolog. (498 aa)
	SMAD5	Mothers against decapentaplegic homolog. (465 aa)
	SKIL	Ski-like protein isoform X1. (684 aa)

Your Current Organism:

Neomonachus schauinslandi

NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC110583310	SKI	A0A2Y9HI04	A0A2Y9GKP9	Mothers against decapentaplegic homolog.	Ski oncogene isoform X1.	0.875
LOC110583310	SKIL	A0A2Y9HI04	A0A2Y9I3E4	Mothers against decapentaplegic homolog.	Ski-like protein isoform X1.	0.798
LOC110583310	SMAD1	A0A2Y9HI04	A0A2Y9G7S1	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.839
LOC110583310	SMAD3	A0A2Y9HI04	A0A2Y9HII2	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.965
LOC110583310	SMAD4	A0A2Y9HI04	A0A2Y9GS17	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.993
LOC110583310	SMAD5	A0A2Y9HI04	A0A2Y9I186	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.577
LOC110583310	SMAD6	A0A2Y9HI04	A0A2Y9HJN0	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.862
LOC110583310	SMAD7	A0A2Y9HI04	A0A2Y9GVZ8	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.883
LOC110583310	SMAD9	A0A2Y9HI04	A0A2Y9G876	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.586
LOC110583310	SMURF1	A0A2Y9HI04	A0A2Y9GA65	Mothers against decapentaplegic homolog.	E3 ubiquitin-protein ligase.	0.797
LOC110583310	SMURF2	A0A2Y9HI04	A0A2Y9G4V4	Mothers against decapentaplegic homolog.	E3 ubiquitin-protein ligase.	0.979
SKI	LOC110583310	A0A2Y9GKP9	A0A2Y9HI04	Ski oncogene isoform X1.	Mothers against decapentaplegic homolog.	0.875
SKI	SKIL	A0A2Y9GKP9	A0A2Y9I3E4	Ski oncogene isoform X1.	Ski-like protein isoform X1.	0.620
SKI	SMAD1	A0A2Y9GKP9	A0A2Y9G7S1	Ski oncogene isoform X1.	Mothers against decapentaplegic homolog.	0.774
SKI	SMAD3	A0A2Y9GKP9	A0A2Y9HII2	Ski oncogene isoform X1.	Mothers against decapentaplegic homolog.	0.871
SKI	SMAD4	A0A2Y9GKP9	A0A2Y9GS17	Ski oncogene isoform X1.	Mothers against decapentaplegic homolog.	0.971
SKI	SMAD5	A0A2Y9GKP9	A0A2Y9I186	Ski oncogene isoform X1.	Mothers against decapentaplegic homolog.	0.769
SKI	SMAD9	A0A2Y9GKP9	A0A2Y9G876	Ski oncogene isoform X1.	Mothers against decapentaplegic homolog.	0.768
SKIL	LOC110583310	A0A2Y9I3E4	A0A2Y9HI04	Ski-like protein isoform X1.	Mothers against decapentaplegic homolog.	0.798
SKIL	SKI	A0A2Y9I3E4	A0A2Y9GKP9	Ski-like protein isoform X1.	Ski oncogene isoform X1.	0.620