STRINGSTRING
ITSN1 ITSN1 GAK GAK DNAJC6 DNAJC6 SGIP1 SGIP1 REPS2 REPS2 AP2S1 AP2S1 STON2 STON2 AP2A1 AP2A1 EPN1 EPN1 NECAP2 NECAP2 EPS15 EPS15 DNM3 DNM3 FCHO1 FCHO1 EPS15L1 EPS15L1 CTTN CTTN PICALM PICALM SLA2 SLA2 ENTHD1 ENTHD1 CLTCL1 CLTCL1 CLTA CLTA AP2A2 AP2A2 NECAP1 NECAP1 SNAP91 SNAP91 SNX9 SNX9 DNM1 DNM1 HCLS1 HCLS1 AP2M1 AP2M1 LOC110583175 LOC110583175 SNX33 SNX33 EPN2 EPN2 ITSN2 ITSN2 BIN1 BIN1 SORL1 SORL1 SNX18 SNX18 LOC110588744 LOC110588744 WASL WASL HIP1 HIP1 HIP1R HIP1R CLTB CLTB CLHC1 CLHC1 AAK1 AAK1 AMPH AMPH EPN3 EPN3 CLTC CLTC FCHO2 FCHO2 AP2B1 AP2B1 DNM2 DNM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITSN1Intersectin-1. (1220 aa)
GAKcyclin-G-associated kinase. (1296 aa)
DNAJC6Putative tyrosine-protein phosphatase auxilin isoform X1. (973 aa)
SGIP1SH3-containing GRB2-like protein 3-interacting protein 1. (908 aa)
REPS2ralBP1-associated Eps domain-containing protein 2 isoform X1. (648 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
STON2Stonin-2; Belongs to the Stoned B family. (695 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
EPN1Epsin-1. (569 aa)
NECAP2Adaptin ear-binding coat-associated protein 2 isoform X4. (275 aa)
EPS15Epidermal growth factor receptor substrate 15 isoform X1. (899 aa)
DNM3Dynamin-3 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (871 aa)
FCHO1F-BAR domain only protein 1 isoform X1. (941 aa)
EPS15L1Epidermal growth factor receptor substrate 15-like 1 isoform X6. (910 aa)
CTTNSrc substrate cortactin isoform X1. (543 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein isoform X1. (653 aa)
SLA2Src-like-adapter 2. (276 aa)
ENTHD1ENTH domain-containing protein 1. (610 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1673 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (218 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (936 aa)
NECAP1Adaptin ear-binding coat-associated protein 1. (274 aa)
SNAP91Clathrin coat assembly protein AP180. (899 aa)
SNX9Sorting nexin. (588 aa)
DNM1LOW QUALITY PROTEIN: dynamin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (867 aa)
HCLS1Hematopoietic lineage cell-specific protein. (474 aa)
AP2M1AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
LOC110583175Sorting nexin-9-like. (427 aa)
SNX33Sorting nexin. (570 aa)
EPN2Epsin-2 isoform X1. (614 aa)
ITSN2Intersectin-2 isoform X1. (1657 aa)
BIN1Myc box-dependent-interacting protein 1 isoform X4. (594 aa)
SORL1Sortilin-related receptor. (2211 aa)
SNX18Sorting nexin. (624 aa)
LOC110588744Uncharacterized protein FLJ45252-like. (337 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (505 aa)
HIP1Huntingtin-interacting protein 1. (913 aa)
HIP1RHuntingtin-interacting protein 1-related protein isoform X1. (1068 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (211 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (586 aa)
AAK1AP2-associated protein kinase 1. (959 aa)
AMPHAmphiphysin isoform X1. (686 aa)
EPN3Epsin-3 isoform X1. (634 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
FCHO2LOW QUALITY PROTEIN: F-BAR domain only protein 2. (866 aa)
AP2B1AP complex subunit beta. (951 aa)
DNM2Dynamin-2 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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