STRINGSTRING
GDF2 GDF2 LRG1 LRG1 CDH13 CDH13 ITGB3 ITGB3 PRKCA PRKCA FGFBP1 FGFBP1 PGF PGF HMGB1 HMGB1 PDCL3 PDCL3 AKT1 AKT1 ZNF580 ZNF580 IL10 IL10 VASH2 VASH2 PROX1 PROX1 FGF2 FGF2 AKT3 AKT3 LOC110573272 LOC110573272 PRKD2 PRKD2 EMC10 EMC10 CCR3 CCR3 STAT3 STAT3 JUN JUN APLNR APLNR VEGFB VEGFB PIK3CD PIK3CD PDCD6 PDCD6 JCAD JCAD SP1 SP1 BMP2 BMP2 HMOX1 HMOX1 PDGFB PDGFB F3 F3 HTR2B HTR2B ECM1 ECM1 LOC110579526 LOC110579526 EGFL7 EGFL7 NRAS NRAS HRAS HRAS FLT4 FLT4 PROK1 PROK1 NRARP NRARP VIP VIP FGF7 FGF7 VEGFA VEGFA TGFBR1 TGFBR1 VEGFC VEGFC SCG2 SCG2 BMP6 BMP6 PRKD1 PRKD1 PDPK1 PDPK1 FGF10 FGF10 THBS4 THBS4 EGR3 EGR3 CCL24 CCL24 APELA APELA KDR KDR SIRT1 SIRT1 AGGF1 AGGF1 CCL26 CCL26 BMPR2 BMPR2 AKT2 AKT2 BMP4 BMP4 NF1 NF1 ITGA4 ITGA4 ACVRL1 ACVRL1 MYDGF MYDGF SIRT6 SIRT6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GDF2Growth/differentiation factor 2. (429 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (354 aa)
CDH13Cadherin-13. (713 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
FGFBP1Fibroblast growth factor-binding protein 1. (255 aa)
PGFPlacenta growth factor isoform X2; Belongs to the PDGF/VEGF growth factor family. (170 aa)
HMGB1High mobility group protein B1. (215 aa)
PDCL3Phosducin-like protein 3. (240 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ZNF580Zinc finger protein 580. (172 aa)
IL10Interleukin-10. (178 aa)
VASH2Vasohibin-2 isoform X1. (355 aa)
PROX1Prospero homeobox protein 1. (737 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (374 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC110573272Signal transducer and activator of transcription 5A. (478 aa)
PRKD2Serine/threonine-protein kinase D2. (725 aa)
EMC10ER membrane protein complex subunit 10 isoform X1. (262 aa)
CCR3C-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (359 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
JUNTranscription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PDCD6Programmed cell death protein 6 isoform X1. (189 aa)
JCADJunctional protein associated with coronary artery disease. (1371 aa)
SP1Transcription factor Sp1. (786 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (288 aa)
HTR2B5-hydroxytryptamine receptor 2B. (480 aa)
ECM1LOW QUALITY PROTEIN: extracellular matrix protein 1. (550 aa)
LOC110579526Signal transducer and activator of transcription 5A-like. (153 aa)
EGFL7Epidermal growth factor-like protein 7 isoform X1. (306 aa)
NRASGTPase NRas. (189 aa)
HRASGTPase HRas isoform X1. (189 aa)
FLT4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1405 aa)
PROK1Prokineticin-1. (105 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
VIPVIP peptides. (170 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (549 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
SCG2Secretogranin-2. (618 aa)
BMP6Bone morphogenetic protein 6. (490 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (571 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
THBS4Thrombospondin-4 isoform X1. (961 aa)
EGR3Early growth response protein 3. (387 aa)
CCL24C-C motif chemokine 24. (109 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1. (746 aa)
AGGF1Angiogenic factor with G patch and FHA domains 1. (716 aa)
CCL26C-C motif chemokine. (94 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (944 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (456 aa)
NF1Neurofibromin isoform X1. (2841 aa)
ITGA4LOW QUALITY PROTEIN: integrin alpha-4; Belongs to the integrin alpha chain family. (1039 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
MYDGFMyeloid-derived growth factor. (272 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (359 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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