STRINGSTRING
PHLDB2 PHLDB2 ACVRL1 ACVRL1 NF1 NF1 CORO1C CORO1C PIK3R1 PIK3R1 RASA1 RASA1 DMTN DMTN PTEN PTEN ITGB1BP1 ITGB1BP1 THBS1 THBS1 BCL6 BCL6 APOD APOD SEMA3E SEMA3E HOXA7 HOXA7 JAG1 JAG1 NEXMIF NEXMIF RCC2 RCC2 ARHGAP6 ARHGAP6 MYOC MYOC AJAP1 AJAP1 ADAM15 ADAM15 ACER2 ACER2 CASK CASK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PHLDB2Pleckstrin homology-like domain family B member 2. (1242 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
NF1Neurofibromin isoform X1. (2841 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
RASA1Ras GTPase-activating protein 1 isoform X1. (1039 aa)
DMTNDematin. (405 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
ITGB1BP1Integrin beta-1-binding protein 1. (200 aa)
THBS1Thrombospondin-1. (1170 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
APODApolipoprotein D. (188 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (715 aa)
HOXA7Homeobox protein Hox-A7. (234 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
NEXMIFProtein KIAA2022 homolog. (1514 aa)
RCC2Protein RCC2. (292 aa)
ARHGAP6LOW QUALITY PROTEIN: rho GTPase-activating protein 6. (981 aa)
MYOCMyocilin. (490 aa)
AJAP1Adherens junction-associated protein 1. (401 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (893 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
CASKPeripheral plasma membrane protein CASK; Belongs to the MAGUK family. (853 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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