STRINGSTRING
AGER AGER NF1 NF1 SMO SMO VIM VIM PLP1 PLP1 DLL1 DLL1 EIF2B5 EIF2B5 TREML1 TREML1 TREM2 TREM2 TLR4 TLR4 LAMC3 LAMC3 KRAS KRAS TSPAN2 TSPAN2 LAMB2 LAMB2 CNTF CNTF S100A9 S100A9 C1QA C1QA S100A8 S100A8 GFAP GFAP C5AR1 C5AR1 S100B S100B IFNG IFNG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGERLOW QUALITY PROTEIN: advanced glycosylation end product-specific receptor. (407 aa)
NF1Neurofibromin isoform X1. (2841 aa)
SMOSmoothened homolog isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
PLP1Myelin proteolipid protein isoform X1. (277 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
EIF2B5Translation initiation factor eIF-2B subunit epsilon. (720 aa)
TREML1Trem-like transcript 1 protein. (312 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
LAMC3Laminin subunit gamma-3. (1576 aa)
KRASGTPase KRas. (188 aa)
TSPAN2Tetraspanin. (221 aa)
LAMB2Laminin subunit beta-2. (1801 aa)
CNTFCiliary neurotrophic factor. (199 aa)
S100A9Protein S100; Belongs to the S-100 family. (135 aa)
C1QAComplement C1q subcomponent subunit A. (245 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
GFAPGlial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family. (432 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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