STRINGSTRING
PDPN PDPN TSKU TSKU TCAP TCAP IL18BP IL18BP ACVR1 ACVR1 CCR7 CCR7 IL6ST IL6ST CD74 CD74 LOC110591944 LOC110591944 LOC110592162 LOC110592162 BMPR2 BMPR2 ZFP36 ZFP36 IL31RA IL31RA KIT KIT LTBP4 LTBP4 CSF1R CSF1R OSMR OSMR IL9R IL9R IL12B IL12B BMPR1A BMPR1A WFIKKN1 WFIKKN1 BMPER BMPER KCP KCP IL2RA IL2RA CXCR5 CXCR5 VASN VASN CXCR4 CXCR4 IL1RN IL1RN LTBP1 LTBP1 IL36RN IL36RN IL5RA IL5RA UCMA UCMA LIFR LIFR CCR6 CCR6 IL20RA IL20RA GREM1 GREM1 IFNGR1 IFNGR1 CHRD CHRD TRIM16 TRIM16 NRROS NRROS TGFBR1 TGFBR1 IL22RA2 IL22RA2 CD109 CD109 CNTFR CNTFR IL17F IL17F TWSG1 TWSG1 ENG ENG TRAF2 TRAF2 TNFRSF1A TNFRSF1A TGFBR3 TGFBR3 SOSTDC1 SOSTDC1 GDF5 GDF5 TNFRSF11A TNFRSF11A COPS5 COPS5 HFE2 HFE2 IL2RB IL2RB LTBP3 LTBP3 IL13RA1 IL13RA1 CHRDL1 CHRDL1 FZD4 FZD4 IL13RA2 IL13RA2 SCUBE3 SCUBE3 ITGB1 ITGB1 TNFRSF9 TNFRSF9 TNFRSF14 TNFRSF14 COMP COMP CCRL2 CCRL2 PARK7 PARK7 LOC110574371 LOC110574371 IL22RA1 IL22RA1 GREM2 GREM2 CSF3R CSF3R HAX1 HAX1 TNFRSF1B TNFRSF1B LOC110574723 LOC110574723 SOST SOST CXCR6 CXCR6 IL12RB1 IL12RB1 CRLF1 CRLF1 CCR3 CCR3 ACKR1 ACKR1 LOC110574374 LOC110574374 LOC110574370 LOC110574370 CCR10 CCR10 FGF2 FGF2 KLHL20 KLHL20 CER1 CER1 TMC8 TMC8 IL6R IL6R IL1RL1 IL1RL1 BMPR1B BMPR1B IL1R2 IL1R2 IL23R IL23R CXCR3 CXCR3 PLP2 PLP2 IL2RG IL2RG IL18R1 IL18R1 TGFBR2 TGFBR2 IL12RB2 IL12RB2 LEPR LEPR TGFB3 TGFB3 HMGB1 HMGB1 IL20RB IL20RB ACKR3 ACKR3 ACKR2 ACKR2 ACKR4 ACKR4 IL3RA IL3RA CRLF2 CRLF2 ITGB3 ITGB3 IFNAR1 IFNAR1 CCR4 CCR4 EBI3 EBI3 IL27RA IL27RA LRRC32 LRRC32 CCR8 CCR8 NOG NOG ITGAV ITGAV CX3CR1 CX3CR1 TGFBR3L TGFBR3L LOC110594100 LOC110594100 CSF2RA CSF2RA ACVRL1 ACVRL1 CHRDL2 CHRDL2 ITGA4 ITGA4 WFIKKN2 WFIKKN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDPNPodoplanin. (142 aa)
TSKUTsukushin. (442 aa)
TCAPTelethonin. (167 aa)
IL18BPInterleukin-18-binding protein isoform X1. (188 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
CCR7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
IL6STInterleukin-6 receptor subunit beta isoform X1. (914 aa)
CD74HLA class II histocompatibility antigen gamma chain isoform X1. (279 aa)
LOC110591944C-X-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (356 aa)
LOC110592162C-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family. (355 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (944 aa)
ZFP36mRNA decay activator protein ZFP36. (325 aa)
IL31RAInterleukin-31 receptor subunit alpha. (747 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
LTBP4Latent-transforming growth factor beta-binding protein 4. (1602 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (962 aa)
OSMRoncostatin-M-specific receptor subunit beta isoform X1. (983 aa)
IL9RInterleukin-9 receptor. (470 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
WFIKKN1WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1. (548 aa)
BMPERBMP-binding endothelial regulator protein. (685 aa)
KCPKielin/chordin-like protein. (1508 aa)
IL2RAInterleukin-2 receptor subunit alpha. (300 aa)
CXCR5C-X-C chemokine receptor type 5 isoform X2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
VASNVasorin. (708 aa)
CXCR4C-X-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
IL1RNInterleukin-1. (223 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1. (1393 aa)
IL36RNInterleukin-1. (155 aa)
IL5RAInterleukin-5 receptor subunit alpha. (419 aa)
UCMAUnique cartilage matrix-associated protein isoform X1. (138 aa)
LIFRLeukemia inhibitory factor receptor. (1097 aa)
CCR6C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (370 aa)
IL20RAInterleukin-20 receptor subunit alpha. (567 aa)
GREM1Gremlin. (184 aa)
IFNGR1LOW QUALITY PROTEIN: interferon gamma receptor 1. (474 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (939 aa)
TRIM16Tripartite motif-containing protein 16. (558 aa)
NRROSNegative regulator of reactive oxygen species. (691 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
IL22RA2Interleukin-22 receptor subunit alpha-2. (231 aa)
CD109CD109 antigen. (1392 aa)
CNTFRCiliary neurotrophic factor receptor subunit alpha. (371 aa)
IL17Finterleukin-17F. (163 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
ENGEndoglin. (650 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (451 aa)
TGFBR3Transforming growth factor beta receptor type 3. (879 aa)
SOSTDC1Sclerostin domain-containing protein 1. (208 aa)
GDF5Growth/differentiation factor 5. (499 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A. (652 aa)
COPS5COP9 signalosome complex subunit 5 isoform X1. (334 aa)
HFE2Hemojuvelin. (428 aa)
IL2RBInterleukin-2 receptor subunit beta. (555 aa)
LTBP3Latent-transforming growth factor beta-binding protein 3 isoform X1. (1298 aa)
IL13RA1Interleukin-13 receptor subunit alpha-1. (286 aa)
CHRDL1Chordin-like protein 1. (459 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
IL13RA2Interleukin-13 receptor subunit alpha-2. (386 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 3. (990 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
TNFRSF9Tumor necrosis factor receptor superfamily member 9. (254 aa)
TNFRSF14Tumor necrosis factor receptor superfamily member 14 isoform X1. (311 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
CCRL2C-C chemokine receptor-like 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. (466 aa)
PARK7LOW QUALITY PROTEIN: protein DJ-1-like. (189 aa)
LOC110574371C-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family. (373 aa)
IL22RA1Interleukin-22 receptor subunit alpha-1. (580 aa)
GREM2Gremlin. (168 aa)
CSF3RGranulocyte colony-stimulating factor receptor isoform X1. (851 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (280 aa)
TNFRSF1BTumor necrosis factor receptor superfamily member 1B isoform X1. (464 aa)
LOC110574723Neuroblastoma suppressor of tumorigenicity 1. (175 aa)
SOSTSclerostin. (213 aa)
CXCR6C-X-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (341 aa)
IL12RB1Interleukin-12 receptor subunit beta-1. (720 aa)
CRLF1Cytokine receptor-like factor 1. (446 aa)
CCR3C-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (359 aa)
ACKR1Atypical chemokine receptor 1. (331 aa)
LOC110574374C-C chemokine receptor type 1-like; Belongs to the G-protein coupled receptor 1 family. (355 aa)
LOC110574370C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
CCR10C-C chemokine receptor type 10; Belongs to the G-protein coupled receptor 1 family. (363 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (374 aa)
KLHL20Kelch-like protein 20. (609 aa)
CER1Cerberus. (274 aa)
TMC8Transmembrane channel-like protein. (723 aa)
IL6RInterleukin-6 receptor subunit alpha. (483 aa)
IL1RL1Interleukin-1 receptor-like 1. (556 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
IL1R2Interleukin-1 receptor type 2 isoform X1. (418 aa)
IL23RInterleukin-23 receptor. (631 aa)
CXCR3C-X-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (291 aa)
PLP2Proteolipid protein 2. (153 aa)
IL2RGCytokine receptor common subunit gamma. (374 aa)
IL18R1Interleukin-18 receptor 1. (540 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
IL12RB2Interleukin-12 receptor subunit beta-2 isoform X1. (861 aa)
LEPRLeptin receptor. (1166 aa)
TGFB3Transforming growth factor beta-3. (461 aa)
HMGB1High mobility group protein B1. (215 aa)
IL20RBInterleukin-20 receptor subunit beta isoform X1. (294 aa)
ACKR3Atypical chemokine receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
ACKR2Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (386 aa)
ACKR4Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
IL3RAInterleukin-3 receptor subunit alpha. (376 aa)
CRLF2Cytokine receptor-like factor 2. (370 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
IFNAR1Interferon alpha/beta receptor 1. (560 aa)
CCR4C-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
EBI3Interleukin-27 subunit beta isoform X1. (258 aa)
IL27RALOW QUALITY PROTEIN: interleukin-27 receptor subunit alpha. (655 aa)
LRRC32Leucine-rich repeat-containing protein 32. (663 aa)
CCR8C-C chemokine receptor type 8; Belongs to the G-protein coupled receptor 1 family. (355 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ITGAVIntegrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1047 aa)
CX3CR1CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
TGFBR3LLOW QUALITY PROTEIN: transforming growth factor-beta receptor type 3-like protein. (403 aa)
LOC110594100LOW QUALITY PROTEIN: neutrophil elastase-like; Belongs to the peptidase S1 family. (284 aa)
CSF2RAGranulocyte-macrophage colony-stimulating factor receptor subunit alpha. (436 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
CHRDL2Chordin-like protein 2. (430 aa)
ITGA4LOW QUALITY PROTEIN: integrin alpha-4; Belongs to the integrin alpha chain family. (1039 aa)
WFIKKN2WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2. (573 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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