STRINGSTRING
PPP1R9B PPP1R9B ABI3 ABI3 ITGAV ITGAV VILL VILL MYO1G MYO1G INPPL1 INPPL1 PAK1 PAK1 BCAR1 BCAR1 LOC110592846 LOC110592846 IGF2BP1 IGF2BP1 LOC110591567 LOC110591567 CORO6 CORO6 CARMIL2 CARMIL2 DBNL DBNL FLOT2 FLOT2 CORO1C CORO1C PDLIM4 PDLIM4 LOC110590731 LOC110590731 APC APC CORO1A CORO1A LIMK1 LIMK1 PKD2 PKD2 SNX2 SNX2 SHTN1 SHTN1 DPYSL3 DPYSL3 LOC110590587 LOC110590587 PALLD PALLD CCDC88A CCDC88A PLEKHH2 PLEKHH2 ABLIM3 ABLIM3 PLCE1 PLCE1 IQGAP2 IQGAP2 FGD1 FGD1 FSCN3 FSCN3 WASL WASL ACTG2 ACTG2 SH3RF1 SH3RF1 AIF1 AIF1 PTK2B PTK2B CARMIL1 CARMIL1 STX2 STX2 CARMIL3 CARMIL3 AJUBA AJUBA CAPG CAPG RHOB RHOB ITGB1BP1 ITGB1BP1 ACTC1 ACTC1 MYH10 MYH10 FLOT1 FLOT1 LOC110584353 LOC110584353 ACTA2 ACTA2 ACTR3 ACTR3 ARHGEF7 ARHGEF7 LOC110583095 LOC110583095 PLXND1 PLXND1 WASF1 WASF1 ACTR3B ACTR3B CDK5 CDK5 BRK1 BRK1 LOC110582646 LOC110582646 ACTA1 ACTA1 FAT1 FAT1 SNX1 SNX1 LOC110583306 LOC110583306 PODXL PODXL LOC110582708 LOC110582708 ARHGAP31 ARHGAP31 PIK3CA PIK3CA PKN2 PKN2 GSN GSN SPEF1 SPEF1 FAM206A FAM206A TSC1 TSC1 TESK1 TESK1 PABPC1 PABPC1 KCNA1 KCNA1 RAB13 RAB13 KCNA2 KCNA2 LOC110578214 LOC110578214 PDXP PDXP LOC110577769 LOC110577769 RAC2 RAC2 LOC110577584 LOC110577584 PLCG1 PLCG1 RHOA RHOA SH3BP1 SH3BP1 ABI1 ABI1 STMN2 STMN2 PIP5K1A PIP5K1A PARVB PARVB APBB1 APBB1 KITLG KITLG CLRN1 CLRN1 LOC110577613 LOC110577613 DAG1 DAG1 CAPRIN1 CAPRIN1 STX3 STX3 AMOT AMOT ARHGEF6 ARHGEF6 ROCK1 ROCK1 CDC42 CDC42 EPHA2 EPHA2 ITGB1 ITGB1 PARVA PARVA ILK ILK CTTN CTTN DGKZ DGKZ CD44 CD44 LOC110576215 LOC110576215 CORO1B CORO1B CFL1 CFL1 FAM89B FAM89B PDPN PDPN PHACTR4 PHACTR4 WASF2 WASF2 SCYL3 SCYL3 HAX1 HAX1 LOC110573152 LOC110573152 CIB3 CIB3 VAMP7 VAMP7 ARPC5 ARPC5 P4HB P4HB UNC5C UNC5C FSCN1 FSCN1 KPTN KPTN VASP VASP ACTN1 ACTN1 ARPIN ARPIN RAC3 RAC3 CYFIP1 CYFIP1 CIB1 CIB1 GDPD2 GDPD2 RAC1 RAC1 CDC42BPB CDC42BPB EVL EVL WASF3 WASF3 ITGB3 ITGB3 SPATA13 SPATA13 RAPGEF3 RAPGEF3 MYO10 MYO10 VIL1 VIL1 ABI2 ABI2 ALS2 ALS2 DPP4 DPP4 NF2 NF2 APC2 APC2 TTN TTN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP1R9BNeurabin-2. (285 aa)
ABI3ABI gene family member 3 isoform X1. (366 aa)
ITGAVIntegrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1047 aa)
VILLVillin-like protein. (859 aa)
MYO1GUnconventional myosin-Ig; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1264 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1. (865 aa)
LOC110592846Nucleoside diphosphate kinase. (152 aa)
IGF2BP1Insulin-like growth factor 2 mRNA-binding protein 1 isoform X1. (577 aa)
LOC110591567Unconventional myosin-X-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (423 aa)
CORO6Coronin; Belongs to the WD repeat coronin family. (472 aa)
CARMIL2Capping protein, Arp2/3 and myosin-I linker protein 2. (1374 aa)
DBNLDrebrin-like protein isoform X1. (415 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
PDLIM4PDZ and LIM domain protein 4 isoform X1. (331 aa)
LOC110590731Nesprin-2-like. (2718 aa)
APCAdenomatous polyposis coli protein. (2844 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
LIMK1LIM domain kinase 1. (644 aa)
PKD2Polycystin-2. (970 aa)
SNX2Sorting nexin-2. (519 aa)
SHTN1Shootin-1 isoform X1. (631 aa)
DPYSL3Dihydropyrimidinase-related protein 3. (687 aa)
LOC110590587Nesprin-2-like. (801 aa)
PALLDPalladin isoform X1. (1177 aa)
CCDC88AGirdin. (1798 aa)
PLEKHH2Pleckstrin homology domain-containing family H member 2. (1493 aa)
ABLIM3Actin-binding LIM protein 3 isoform X3. (650 aa)
PLCE1Phosphoinositide phospholipase C. (2299 aa)
IQGAP2LOW QUALITY PROTEIN: ras GTPase-activating-like protein IQGAP2. (1572 aa)
FGD1FYVE, RhoGEF and PH domain-containing protein 1. (960 aa)
FSCN3Fascin. (497 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (505 aa)
ACTG2Actin, gamma-enteric smooth muscle. (376 aa)
SH3RF1LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase SH3RF1. (873 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1010 aa)
CARMIL1F-actin-uncapping protein LRRC16A. (1373 aa)
STX2Syntaxin-2; Belongs to the syntaxin family. (322 aa)
CARMIL3Capping protein, Arp2/3 and myosin-I linker protein 3. (1372 aa)
AJUBALIM domain-containing protein ajuba. (548 aa)
CAPGMacrophage-capping protein. (349 aa)
RHOBRho-related GTP-binding protein RhoB. (196 aa)
ITGB1BP1Integrin beta-1-binding protein 1. (200 aa)
ACTC1Actin, alpha cardiac muscle 1 isoform X1. (377 aa)
MYH10Myosin-10 isoform X5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
LOC110584353Neurabin-2-like. (242 aa)
ACTA2Actin, aortic smooth muscle. (377 aa)
ACTR3Actin-related protein 3; Belongs to the actin family. (418 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7 isoform X1. (646 aa)
LOC110583095Zinc transporter ZIP6-like. (436 aa)
PLXND1plexin-D1. (1927 aa)
WASF1wiskott-Aldrich syndrome protein family member 1 isoform X1. (559 aa)
ACTR3BActin-related protein 3B isoform X1; Belongs to the actin family. (418 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
BRK1Protein BRICK1. (75 aa)
LOC110582646Myosin light chain kinase, smooth muscle-like. (488 aa)
ACTA1Actin, alpha skeletal muscle. (377 aa)
FAT1LOW QUALITY PROTEIN: protocadherin Fat 1. (4588 aa)
SNX1Sorting nexin-1 isoform X1. (521 aa)
LOC110583306Zinc transporter ZIP6. (219 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (561 aa)
LOC110582708Myosin light chain kinase, smooth muscle isoform X1. (865 aa)
ARHGAP31Rho GTPase-activating protein 31. (1448 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PKN2Serine/threonine-protein kinase N2. (984 aa)
GSNGelsolin isoform X1. (777 aa)
SPEF1Sperm flagellar protein 1. (236 aa)
FAM206AProtein Simiate. (181 aa)
TSC1Hamartin. (1168 aa)
TESK1Dual specificity testis-specific protein kinase 1. (628 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
RAB13Ras-related protein Rab-13. (203 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2 isoform X1; Belongs to the potassium channel family. (499 aa)
LOC110578214Neurabin-2-like. (98 aa)
PDXPPyridoxal phosphate phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa)
LOC110577769Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
LOC110577584Death domain-containing membrane protein NRADD-like isoform X1. (250 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1289 aa)
RHOATransforming protein RhoA. (193 aa)
SH3BP1SH3 domain-binding protein 1 isoform X1. (690 aa)
ABI1Abl interactor 1 isoform X8. (507 aa)
STMN2Stathmin; Belongs to the stathmin family. (179 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa)
PARVBBeta-parvin. (327 aa)
APBB1Amyloid beta A4 precursor protein-binding family B member 1. (708 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
CLRN1Clarin-1. (232 aa)
LOC110577613Myosin light chain kinase, smooth muscle-like. (294 aa)
DAG1Dystroglycan. (891 aa)
CAPRIN1Caprin-1. (709 aa)
STX3Syntaxin-3. (184 aa)
AMOTAngiomotin. (1067 aa)
ARHGEF6Rho guanine nucleotide exchange factor 6. (771 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
CDC42Cell division control protein 42 homolog. (191 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
PARVAAlpha-parvin. (342 aa)
ILKIntegrin-linked protein kinase isoform X1. (452 aa)
CTTNSrc substrate cortactin isoform X1. (543 aa)
DGKZDiacylglycerol kinase. (1130 aa)
CD44CD44 antigen isoform X1. (785 aa)
LOC110576215Actin, alpha skeletal muscle 2-like. (436 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (489 aa)
CFL1Cofilin-1; Belongs to the actin-binding proteins ADF family. (219 aa)
FAM89BProtein FAM89B. (192 aa)
PDPNPodoplanin. (142 aa)
PHACTR4Phosphatase and actin regulator. (705 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (499 aa)
SCYL3Protein-associating with the carboxyl-terminal domain of ezrin isoform X2. (742 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (280 aa)
LOC110573152Allograft inflammatory factor 1. (147 aa)
CIB3Calcium and integrin-binding family member 3 isoform X1. (187 aa)
VAMP7Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
P4HBProtein disulfide-isomerase. (510 aa)
UNC5CNetrin receptor UNC5C. (931 aa)
FSCN1Fascin. (493 aa)
KPTNKaptin. (435 aa)
VASPVasodilator-stimulated phosphoprotein isoform X1; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (382 aa)
ACTN1Alpha-actinin-1. (846 aa)
ARPINArpin isoform X1. (231 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (195 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
CIB1Calcium and integrin-binding protein 1 isoform X1. (215 aa)
GDPD2Glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform X1. (548 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
CDC42BPBSerine/threonine-protein kinase MRCK beta isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1712 aa)
EVLena/VASP-like protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (420 aa)
WASF3wiskott-Aldrich syndrome protein family member 3. (502 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
SPATA13Spermatogenesis-associated protein 13 isoform X1. (1246 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (881 aa)
MYO10Unconventional myosin-X. (945 aa)
VIL1Villin-1. (827 aa)
ABI2Abl interactor 2. (475 aa)
ALS2Alsin. (1657 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
NF2Merlin isoform X1. (596 aa)
APC2Adenomatous polyposis coli protein 2 isoform X1. (2265 aa)
TTNLOW QUALITY PROTEIN: titin. (32000 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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