STRINGSTRING
PTEN PTEN NLGN2 NLGN2 NALCN NALCN PHF24 PHF24 STXBP1 STXBP1 KRAS KRAS KIF5B KIF5B ADORA2A ADORA2A NPAS4 NPAS4 PLCL1 PLCL1 NF1 NF1 NPS NPS PRKCE PRKCE CLN3 CLN3 BAIAP3 BAIAP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
NLGN2Neuroligin-2. (835 aa)
NALCNSodium leak channel non-selective protein isoform X1. (1767 aa)
PHF24PHD finger protein 24. (400 aa)
STXBP1Syntaxin-binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
KRASGTPase KRas. (188 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
NPAS4Neuronal PAS domain-containing protein 4 isoform X1. (800 aa)
PLCL1Phosphoinositide phospholipase C. (1096 aa)
NF1Neurofibromin isoform X1. (2841 aa)
NPSNeuropeptide S. (129 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
CLN3Battenin. (485 aa)
BAIAP3BAI1-associated protein 3 isoform X1. (1172 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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