STRINGSTRING
LOC110569925 LOC110569925 GPR143 GPR143 SLC2A9 SLC2A9 PSEN1 PSEN1 CD34 CD34 PDPN PDPN PRKCZ PRKCZ KIAA1614 KIAA1614 LHFPL5 LHFPL5 SLC22A12 SLC22A12 SLC3A2 SLC3A2 OCEL1 OCEL1 TCIRG1 TCIRG1 SLC22A18 SLC22A18 SLC22A11 SLC22A11 KCNQ1 KCNQ1 CD44 CD44 SPTBN2 SPTBN2 SVBP SVBP INSC INSC USH1C USH1C PARD6B PARD6B MYO5B MYO5B PARD6G PARD6G KNCN KNCN RAB18 RAB18 STX3 STX3 OTOA OTOA SLC26A6 SLC26A6 ANO1 ANO1 SLC38A3 SLC38A3 SLC6A18 SLC6A18 SLC9A3 SLC9A3 SLC5A12 SLC5A12 ACY3 ACY3 MIP MIP MYO1A MYO1A LOC110577921 LOC110577921 PARD3 PARD3 NEDD1 NEDD1 UPK3A UPK3A DSTYK DSTYK CTSK CTSK SCNN1B SCNN1B LRRC6 LRRC6 ANXA13 ANXA13 SLC26A9 SLC26A9 ERBB3 ERBB3 SCNN1G SCNN1G SLC4A11 SLC4A11 ZMYND10 ZMYND10 JAG1 JAG1 SLC6A19 SLC6A19 SLC16A8 SLC16A8 CD36 CD36 SNX10 SNX10 FZD6 FZD6 PSEN2 PSEN2 STXBP3 STXBP3 DRAM2 DRAM2 CLDND1 CLDND1 MAL2 MAL2 PDZK1 PDZK1 PTPRO PTPRO ATP6V1E1 ATP6V1E1 SLC39A4 SLC39A4 ATP6V0D2 ATP6V0D2 LOC110580990 LOC110580990 SCNN1A SCNN1A ADCY8 ADCY8 CA2 CA2 SAPCD2 SAPCD2 SLC34A3 SLC34A3 SLC23A2 SLC23A2 SPEF1 SPEF1 CRB2 CRB2 ATP6V1G1 ATP6V1G1 AQP1 AQP1 SLC29A1 SLC29A1 CLIC5 CLIC5 CDHR5 CDHR5 P2RX2 P2RX2 CLDN1 CLDN1 ABCC5 ABCC5 SLC2A13 SLC2A13 PODXL PODXL ATP6V0A4 ATP6V0A4 TRPV5 TRPV5 NOTCH1 NOTCH1 SLC46A2 SLC46A2 DLL1 DLL1 ENPP3 ENPP3 SLC22A1 SLC22A1 SLC19A1 SLC19A1 OOEP OOEP LOC110583386 LOC110583386 SLC22A2 SLC22A2 EPB41L4B EPB41L4B EZR EZR KHDC3L KHDC3L SLC12A1 SLC12A1 ADGRF5 ADGRF5 BYSL BYSL FAT1 FAT1 PCM1 PCM1 TRPM6 TRPM6 PKHD1 PKHD1 UPK1B UPK1B DVL2 DVL2 ATP6V1A ATP6V1A CHL1 CHL1 MUC20 MUC20 SLC4A2 SLC4A2 GJA1 GJA1 DUOXA2 DUOXA2 DUOX1 DUOX1 LOC110583493 LOC110583493 SLC10A2 SLC10A2 C1QTNF5 C1QTNF5 THY1 THY1 C2CD2L C2CD2L SLC1A1 SLC1A1 PDZD3 PDZD3 ANXA1 ANXA1 RDX RDX CUBN CUBN RIPOR2 RIPOR2 ATP1B2 ATP1B2 LOC110586704 LOC110586704 PDGFRB PDGFRB SLC44A4 SLC44A4 AGER AGER ATP6V1G2 ATP6V1G2 PROM2 PROM2 LOC110585337 LOC110585337 SLC7A8 SLC7A8 MYO7B MYO7B DUOX2 DUOX2 LCT LCT SLC9A3R2 SLC9A3R2 PTEN PTEN ATP4B ATP4B GP2 GP2 TMEM114 TMEM114 USH2A USH2A KCNK1 KCNK1 CDHR2 CDHR2 SLC39A14 SLC39A14 SLC34A1 SLC34A1 HFE HFE UPK2 UPK2 CTSB CTSB FZD3 FZD3 SLC4A5 SLC4A5 ATP6V1B1 ATP6V1B1 CFTR CFTR PLB1 PLB1 LMO7 LMO7 KCNMA1 KCNMA1 UMOD UMOD EMP2 EMP2 HOMER1 HOMER1 F2RL2 F2RL2 OCLN OCLN SLC30A5 SLC30A5 RAPGEF2 RAPGEF2 SLC5A2 SLC5A2 HIP1R HIP1R ATP6V1B2 ATP6V1B2 UPK1A UPK1A SLC3A1 SLC3A1 ABCG8 ABCG8 ABCG5 ABCG5 FRMD6 FRMD6 NIN NIN ABCC2 ABCC2 SLC22A5 SLC22A5 SLC23A1 SLC23A1 PLPP1 PLPP1 DPEP1 DPEP1 SHROOM3 SHROOM3 ABCG2 ABCG2 MARVELD2 MARVELD2 ABCB11 ABCB11 DYNC2LI1 DYNC2LI1 AQP8 AQP8 LOC110592032 LOC110592032 ATP4A ATP4A SLC4A10 SLC4A10 EXOC1 EXOC1 FXYD1 FXYD1 FN1 FN1 SIPA1L3 SIPA1L3 SLC4A9 SLC4A9 RAPGEF6 RAPGEF6 SHROOM1 SHROOM1 LOC110590695 LOC110590695 PARD6A PARD6A SLC6A4 SLC6A4 SLC46A1 SLC46A1 SLC22A4 SLC22A4 PRKCI PRKCI STK39 STK39 SLC12A2 SLC12A2 LOC110592031 LOC110592031 LOC110592082 LOC110592082 AQP2 AQP2 SLC11A2 SLC11A2 SLC7A5 SLC7A5 DPP4 DPP4 LRP2 LRP2 NF2 NF2 LDLR LDLR ARHGEF18 ARHGEF18 CPO CPO SLC12A3 SLC12A3 NUMA1 NUMA1 RELT RELT AQP6 AQP6 CA4 CA4 FOLR1 FOLR1 AQP5 AQP5 ITPK1 ITPK1 SLC29A4 SLC29A4 EDA EDA EDAR EDAR CUNH2orf40 CUNH2orf40 SLC34A2 SLC34A2 LOC110572151 LOC110572151 CIB1 CIB1 SLC24A4 SLC24A4 MSN MSN PROM1 PROM1 TMEM235 TMEM235 TMEM27 TMEM27 SLC16A3 SLC16A3 AMN AMN CEACAM20 CEACAM20 PLAUR PLAUR C5AR1 C5AR1 C5AR2 C5AR2 PLAT PLAT RHCG RHCG HOMER2 HOMER2 ACE2 ACE2 CFAP126 CFAP126 MUC1 MUC1 SLC39A8 SLC39A8 SHROOM2 SHROOM2 FPR2 FPR2 S100G S100G TEK TEK ATP1B1 ATP1B1 SLC6A20 SLC6A20 CIB3 CIB3 CD300LG CD300LG CETN2 CETN2 CRB1 CRB1 HAX1 HAX1 AKR1A1 AKR1A1 PTPRH PTPRH LOC110575117 LOC110575117 SLC26A4 SLC26A4 SLC9A1 SLC9A1 NUMB NUMB MPP5 MPP5 LGMN LGMN SLC9A3R1 SLC9A3R1 VASH1 VASH1 ATP1B3 ATP1B3 SLC7A11 SLC7A11 PTCH1 PTCH1 UMODL1 UMODL1 SLC7A1 SLC7A1 RAB17 RAB17 SLC4A7 SLC4A7 CLCN5 CLCN5 SHROOM4 SHROOM4 ITGB3 ITGB3 ATP12A ATP12A KCNE1 KCNE1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC110569925Cathepsin L1; Belongs to the peptidase C1 family. (334 aa)
GPR143LOW QUALITY PROTEIN: G-protein coupled receptor 143. (442 aa)
SLC2A9Solute carrier family 2, facilitated glucose transporter member 9 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (578 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
CD34Hematopoietic progenitor cell antigen CD34 isoform X1. (383 aa)
PDPNPodoplanin. (142 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa)
KIAA1614Uncharacterized protein KIAA1614 homolog. (1227 aa)
LHFPL5Tetraspan membrane protein of hair cell stereocilia. (217 aa)
SLC22A12Solute carrier family 22 member 12 isoform X1. (553 aa)
SLC3A24F2 cell-surface antigen heavy chain isoform X2. (533 aa)
OCEL1occludin/ELL domain-containing protein 1. (262 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (846 aa)
SLC22A18Solute carrier family 22 member 18 isoform X1. (424 aa)
SLC22A11Solute carrier family 22 member 11. (556 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (625 aa)
CD44CD44 antigen isoform X1. (785 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2397 aa)
SVBPSmall vasohibin-binding protein. (66 aa)
INSCProtein inscuteable homolog. (579 aa)
USH1CHarmonin. (867 aa)
PARD6BPartitioning defective 6 homolog beta. (370 aa)
MYO5BUnconventional myosin-Vb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1824 aa)
PARD6GPartitioning defective 6 homolog gamma. (363 aa)
KNCNKinocilin. (124 aa)
RAB18Ras-related protein Rab-18. (206 aa)
STX3Syntaxin-3. (184 aa)
OTOAOtoancorin. (1139 aa)
SLC26A6Solute carrier family 26 member 6 isoform X1. (766 aa)
ANO1Anoctamin. (988 aa)
SLC38A3Sodium-coupled neutral amino acid transporter 3. (504 aa)
SLC6A18Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (625 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (841 aa)
SLC5A12Sodium-coupled monocarboxylate transporter 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (619 aa)
ACY3LOW QUALITY PROTEIN: N-acyl-aromatic-L-amino acid amidohydrolase (Carboxylate-forming). (357 aa)
MIPLens fiber major intrinsic protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
MYO1AUnconventional myosin-Ia; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1042 aa)
LOC110577921Na(+)/H(+) exchange regulatory cofactor NHE-RF1-like. (106 aa)
PARD3Partitioning defective 3 homolog isoform X1. (1359 aa)
NEDD1Protein NEDD1. (658 aa)
UPK3AUroplakin-3a isoform X1. (287 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (929 aa)
CTSKCathepsin K isoform X2; Belongs to the peptidase C1 family. (330 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
LRRC6Protein tilB homolog. (470 aa)
ANXA13Annexin. (357 aa)
SLC26A9Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (791 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (646 aa)
SLC4A11Sodium bicarbonate transporter-like protein 11. (875 aa)
ZMYND10Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family. (440 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
SLC6A19Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (634 aa)
SLC16A8Monocarboxylate transporter 3. (508 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
SNX10Sorting nexin-10. (201 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
STXBP3Syntaxin-binding protein 3 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (605 aa)
DRAM2DNA damage-regulated autophagy modulator protein 2 isoform X1. (266 aa)
CLDND1Claudin domain-containing protein 1. (253 aa)
MAL2Protein MAL2 isoform X1. (176 aa)
PDZK1Na(+)/H(+) exchange regulatory cofactor NHE-RF3 isoform X1. (519 aa)
PTPROReceptor-type tyrosine-protein phosphatase O. (1198 aa)
ATP6V1E1V-type proton ATPase subunit E 1. (226 aa)
SLC39A4Zinc transporter ZIP4. (646 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
LOC110580990Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (236 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (649 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
SAPCD2Suppressor APC domain-containing protein 2. (402 aa)
SLC34A3Sodium-dependent phosphate transport protein 2C. (289 aa)
SLC23A2Solute carrier family 23 member 2. (650 aa)
SPEF1Sperm flagellar protein 1. (236 aa)
CRB2Protein crumbs homolog 2. (1110 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SLC29A1Equilibrative nucleoside transporter 1 isoform X1. (490 aa)
CLIC5Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (416 aa)
CDHR5Cadherin-related family member 5. (776 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (471 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
ABCC5Multidrug resistance-associated protein 5 isoform X2. (1437 aa)
SLC2A13Proton myo-inositol cotransporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (646 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (561 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (732 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2567 aa)
SLC46A2Thymic stromal cotransporter homolog. (475 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (921 aa)
SLC22A1LOW QUALITY PROTEIN: solute carrier family 22 member 1. (554 aa)
SLC19A1Folate transporter 1. (344 aa)
OOEPOocyte-expressed protein homolog. (149 aa)
LOC110583386A-kinase anchor protein 7 isoforms alpha and beta. (104 aa)
SLC22A2Solute carrier family 22 member 2 isoform X1. (554 aa)
EPB41L4BBand 4.1-like protein 4B. (863 aa)
EZREzrin isoform X1. (586 aa)
KHDC3LKHDC3-like protein. (226 aa)
SLC12A1Solute carrier family 12 member 1 isoform X1. (1100 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1346 aa)
BYSLBystin isoform X1. (436 aa)
FAT1LOW QUALITY PROTEIN: protocadherin Fat 1. (4588 aa)
PCM1Pericentriolar material 1 protein isoform X1. (2083 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (2020 aa)
PKHD1Fibrocystin. (4075 aa)
UPK1BTetraspanin. (260 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (734 aa)
ATP6V1AV-type proton ATPase catalytic subunit A. (618 aa)
CHL1Neural cell adhesion molecule L1-like protein. (1225 aa)
MUC20Mucin-20. (534 aa)
SLC4A2Anion exchange protein. (1237 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
DUOXA2Dual oxidase maturation factor 2. (320 aa)
DUOX1Dual oxidase 1. (1428 aa)
LOC110583493Sodium-dependent phosphate transport protein 2C-like. (311 aa)
SLC10A2Ileal sodium/bile acid cotransporter. (348 aa)
C1QTNF5Complement C1q tumor necrosis factor-related protein 5 isoform X1. (320 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
C2CD2LPhospholipid transfer protein C2CD2L. (706 aa)
SLC1A1Amino acid transporter. (524 aa)
PDZD3LOW QUALITY PROTEIN: Na(+)/H(+) exchange regulatory cofactor NHE-RF4. (615 aa)
ANXA1Annexin. (345 aa)
RDXRadixin. (583 aa)
CUBNCubilin. (3620 aa)
RIPOR2Protein FAM65B isoform X1. (1043 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
LOC110586704Sodium-dependent phosphate transport protein 1-like. (466 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa)
SLC44A4Choline transporter-like protein 4 isoform X1; Belongs to the CTL (choline transporter-like) family. (709 aa)
AGERLOW QUALITY PROTEIN: advanced glycosylation end product-specific receptor. (407 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (188 aa)
PROM2Prominin-2. (837 aa)
LOC110585337Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
SLC7A8Large neutral amino acids transporter small subunit 2 isoform X1. (537 aa)
MYO7BUnconventional myosin-VIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2079 aa)
DUOX2Dual oxidase 2. (1543 aa)
LCTLactase-phlorizin hydrolase. (1924 aa)
SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF2. (226 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
GP2Pancreatic secretory granule membrane major glycoprotein GP2. (518 aa)
TMEM114Transmembrane protein 114 isoform X2. (223 aa)
USH2AUsherin. (5203 aa)
KCNK1Potassium channel subfamily K member. (326 aa)
CDHR2Cadherin-related family member 2. (1308 aa)
SLC39A14Zinc transporter ZIP14 isoform X1. (490 aa)
SLC34A1Sodium-dependent phosphate transport protein 2A. (639 aa)
HFEHereditary hemochromatosis protein isoform X1; Belongs to the MHC class I family. (356 aa)
UPK2Uroplakin-2. (184 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
SLC4A5Anion exchange protein. (1115 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1573 aa)
PLB1Phospholipase B1, membrane-associated. (1459 aa)
LMO7LIM domain only protein 7 isoform X2. (1412 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1 isoform X2. (1262 aa)
UMODUromodulin. (643 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
HOMER1Homer protein homolog 1. (354 aa)
F2RL2Proteinase-activated receptor 3. (377 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa)
SLC30A5Zinc transporter 5. (767 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1659 aa)
SLC5A2Sodium/glucose cotransporter 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (673 aa)
HIP1RHuntingtin-interacting protein 1-related protein isoform X1. (1068 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
UPK1ATetraspanin. (257 aa)
SLC3A1Neutral and basic amino acid transport protein rBAT. (681 aa)
ABCG8LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 8. (604 aa)
ABCG5LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 5. (622 aa)
FRMD6FERM domain-containing protein 6 isoform X1. (622 aa)
NINNinein. (2131 aa)
ABCC2Canalicular multispecific organic anion transporter 1. (1545 aa)
SLC22A5Solute carrier family 22 member 5. (557 aa)
SLC23A1Solute carrier family 23 member 1. (641 aa)
PLPP1Phospholipid phosphatase 1 isoform X1. (285 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (409 aa)
SHROOM3Protein Shroom3. (1939 aa)
ABCG2ATP-binding cassette sub-family G member 2. (676 aa)
MARVELD2MARVEL domain-containing protein 2. (559 aa)
ABCB11Bile salt export pump isoform X1. (1325 aa)
DYNC2LI1Cytoplasmic dynein 2 light intermediate chain 1. (350 aa)
AQP8Aquaporin-8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
LOC110592032Partitioning defective 3 homolog B-like. (569 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
SLC4A10Anion exchange protein. (1118 aa)
EXOC1Exocyst complex component 1 isoform X1. (894 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
FN1Fibronectin isoform X7. (2476 aa)
SIPA1L3Signal-induced proliferation-associated 1-like protein 3. (1778 aa)
SLC4A9Anion exchange protein. (954 aa)
RAPGEF6LOW QUALITY PROTEIN: rap guanine nucleotide exchange factor 6. (1409 aa)
SHROOM1Protein Shroom1. (886 aa)
LOC110590695V-type proton ATPase subunit E 1-like isoform X1. (226 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (346 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
SLC46A1Proton-coupled folate transporter isoform X1. (538 aa)
SLC22A4Solute carrier family 22 member 4. (553 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
STK39STE20/SPS1-related proline-alanine-rich protein kinase. (542 aa)
SLC12A2Solute carrier family 12 member 2. (1201 aa)
LOC110592031Partitioning defective 3 homolog B-like. (333 aa)
LOC110592082Cytochrome b reductase 1. (284 aa)
AQP2Aquaporin-2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SLC11A2Natural resistance-associated macrophage protein 2. (596 aa)
SLC7A5Large neutral amino acids transporter small subunit 1. (394 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
LRP2LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 2. (4645 aa)
NF2Merlin isoform X1. (596 aa)
LDLRLow-density lipoprotein receptor. (861 aa)
ARHGEF18LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 18. (1171 aa)
CPOCarboxypeptidase O. (375 aa)
SLC12A3Solute carrier family 12 member 3 isoform X1. (1031 aa)
NUMA1Nuclear mitotic apparatus protein 1 isoform X1. (2122 aa)
RELTTumor necrosis factor receptor superfamily member 19L. (587 aa)
AQP6LOW QUALITY PROTEIN: aquaporin-6; Belongs to the MIP/aquaporin (TC 1.A.8) family. (273 aa)
CA4Carbonic anhydrase 4; Belongs to the alpha-carbonic anhydrase family. (313 aa)
FOLR1Folate receptor alpha. (254 aa)
AQP5Aquaporin-5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (401 aa)
SLC29A4Equilibrative nucleoside transporter 4. (525 aa)
EDAectodysplasin-A isoform X6; Belongs to the tumor necrosis factor family. (390 aa)
EDARTumor necrosis factor receptor superfamily member EDAR. (446 aa)
CUNH2orf40Augurin. (147 aa)
SLC34A2Sodium-dependent phosphate transport protein 2B. (693 aa)
LOC110572151Melanoregulin-like. (213 aa)
CIB1Calcium and integrin-binding protein 1 isoform X1. (215 aa)
SLC24A4Sodium/potassium/calcium exchanger 4 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
MSNMoesin. (577 aa)
PROM1Prominin-1 isoform X1. (848 aa)
TMEM235LOW QUALITY PROTEIN: transmembrane protein 235. (195 aa)
TMEM27Collectrin. (116 aa)
SLC16A3Monocarboxylate transporter 4. (460 aa)
AMNProtein amnionless. (465 aa)
CEACAM20Carcinoembryonic antigen-related cell adhesion molecule 20. (480 aa)
PLAURUrokinase plasminogen activator surface receptor. (335 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
C5AR2C5a anaphylatoxin chemotactic receptor 2. (337 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (560 aa)
RHCGAmmonium transporter Rh type C; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (460 aa)
HOMER2Homer protein homolog 2. (279 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
CFAP126Protein Flattop. (220 aa)
MUC1Mucin-1. (339 aa)
SLC39A8Zinc transporter ZIP8. (461 aa)
SHROOM2Protein Shroom2. (441 aa)
FPR2N-formyl peptide receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
S100GProtein S100; Belongs to the S-100 family. (79 aa)
TEKAngiopoietin-1 receptor. (1124 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
SLC6A20Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (592 aa)
CIB3Calcium and integrin-binding family member 3 isoform X1. (187 aa)
CD300LGCMRF35-like molecule 9. (277 aa)
CETN2Centrin-2. (204 aa)
CRB1Protein crumbs homolog 1 isoform X1. (1337 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (280 aa)
AKR1A1Alcohol dehydrogenase [NADP(+)] isoform X1. (325 aa)
PTPRHProtein-tyrosine-phosphatase. (579 aa)
LOC110575117Solute carrier family 2, facilitated glucose transporter member 5; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
NUMBProtein numb homolog isoform X1. (653 aa)
MPP5MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (675 aa)
LGMNLegumain. (433 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF1. (280 aa)
VASH1Vasohibin-1. (363 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta-3. (350 aa)
SLC7A11Cystine/glutamate transporter. (503 aa)
PTCH1Protein patched homolog 1. (1301 aa)
UMODL1Uromodulin-like 1. (1324 aa)
SLC7A1High affinity cationic amino acid transporter 1. (629 aa)
RAB17LOW QUALITY PROTEIN: ras-related protein Rab-17. (161 aa)
SLC4A7Anion exchange protein. (1258 aa)
CLCN5Chloride channel protein. (747 aa)
SHROOM4Protein Shroom4. (1487 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
ATP12APotassium-transporting ATPase alpha chain 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1139 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (124 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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