STRINGSTRING
EXT2 EXT2 WFS1 WFS1 ADD1 ADD1 CYTL1 CYTL1 SOX9 SOX9 VSIG1 VSIG1 BBS10 BBS10 GATA1 GATA1 IL20RB IL20RB PASK PASK TFF3 TFF3 TRPM2 TRPM2 CXADR CXADR TFF1 TFF1 LDB2 LDB2 NPHP3 NPHP3 SPATA7 SPATA7 NR1D2 NR1D2 NKIRAS1 NKIRAS1 PRLH PRLH PIWIL4 PIWIL4 NOX4 NOX4 LEPR LEPR SGIP1 SGIP1 TFF2 TFF2 LRRK1 LRRK1 PROM1 PROM1 PPARGC1A PPARGC1A TJP1 TJP1 CTSH CTSH CD7 CD7 RCN3 RCN3 PPP1R13L PPP1R13L CRTC3 CRTC3 BBS12 BBS12 ADRB3 ADRB3 KLHL10 KLHL10 HOMER2 HOMER2 LOC110573247 LOC110573247 SLC39A8 SLC39A8 NDN NDN SH3GL2 SH3GL2 USH1G USH1G NAPSA NAPSA LOC110574021 LOC110574021 FMO4 FMO4 FH FH HCRT HCRT NKIRAS2 NKIRAS2 NXNL1 NXNL1 STAT3 STAT3 KDF1 KDF1 CRB1 CRB1 NCDN NCDN MFSD2A MFSD2A MTF1 MTF1 TMEM79 TMEM79 ELOVL1 ELOVL1 LOC110574020 LOC110574020 ILDR2 ILDR2 OMA1 OMA1 CROCC CROCC GRHL3 GRHL3 CD34 CD34 CRTC1 CRTC1 NPHP4 NPHP4 FMO2 FMO2 BTBD9 BTBD9 FMO1 FMO1 COMP COMP TCIRG1 TCIRG1 BBS1 BBS1 SFN SFN TFAP2E TFAP2E RRP8 RRP8 TPP1 TPP1 USH1C USH1C TULP1 TULP1 MEX3C MEX3C AQP4 AQP4 PRCP PRCP PM20D1 PM20D1 PNPLA1 PNPLA1 LOC110577685 LOC110577685 PTH PTH SASH3 SASH3 POC1B POC1B CLRN1 CLRN1 TRAF6 TRAF6 TUB TUB WWTR1 WWTR1 CTSK CTSK TNS2 TNS2 TNFRSF11A TNFRSF11A SCNN1B SCNN1B PRDM14 PRDM14 XIAP XIAP SCNN1G SCNN1G TP53INP2 TP53INP2 PTH1R PTH1R LOC110577686 LOC110577686 SRC SRC RB1 RB1 SNX10 SNX10 LOC110578582 LOC110578582 CSF1 CSF1 DRAM2 DRAM2 RP1 RP1 IL7 IL7 ABCA4 ABCA4 LOC110578462 LOC110578462 KRAS KRAS IAPP IAPP HAS2 HAS2 SCNN1A SCNN1A BPIFA1 BPIFA1 EXT1 EXT1 AQP3 AQP3 UGCG UGCG TLR4 TLR4 MKKS MKKS CRB2 CRB2 TRIM32 TRIM32 HOXA13 HOXA13 AQP1 AQP1 SRF SRF TFAP2B TFAP2B NAPEPLD NAPEPLD IL17A IL17A MUC6 MUC6 PIK3CA PIK3CA SQSTM1 SQSTM1 CLDN1 CLDN1 ILDR1 ILDR1 MUC13 MUC13 GPR55 GPR55 LOC110582880 LOC110582880 STRAP STRAP NOTCH1 NOTCH1 MRAP2 MRAP2 CTGF CTGF LRRC45 LRRC45 CLDN5 CLDN5 DLL1 DLL1 WHRN WHRN AQP7 AQP7 USP45 USP45 NOX3 NOX3 SLC35D3 SLC35D3 BBS4 BBS4 ADGRF5 ADGRF5 LOC110584033 LOC110584033 NXNL2 NXNL2 ALDH1A1 ALDH1A1 IQCB1 IQCB1 ALOX12 ALOX12 AIPL1 AIPL1 TP63 TP63 CCDC66 CCDC66 RHO RHO TJP2 TJP2 IL18 IL18 ACADVL ACADVL FLCN FLCN ALOX12B ALOX12B ATP1B2 ATP1B2 MAK MAK BMP6 BMP6 BAP1 BAP1 LOC110584772 LOC110584772 IL1B IL1B STARD7 STARD7 ALK ALK LTK LTK AKAP11 AKAP11 CCDC154 CCDC154 LIPA LIPA USH2A USH2A PTPN11 PTPN11 PTK2B PTK2B YAP1 YAP1 CLCN3 CLCN3 VPS54 VPS54 IL1A IL1A ATP6V1B1 ATP6V1B1 LOC110588803 LOC110588803 ADGRV1 ADGRV1 CFTR CFTR CDH23 CDH23 ERCC6 ERCC6 F2R F2R HOMER1 HOMER1 PBLD PBLD NANOS1 NANOS1 CDHR1 CDHR1 TNFSF11 TNFSF11 SFTPD SFTPD P2RX7 P2RX7 SMO SMO ARRDC3 ARRDC3 EPAS1 EPAS1 KDR KDR SIRT1 SIRT1 LDB1 LDB1 VSTM4 VSTM4 LOC110591485 LOC110591485 CORO1A CORO1A COL3A1 COL3A1 LSR LSR EGR1 EGR1 ABCA12 ABCA12 HNF1A HNF1A MLLT6 MLLT6 ZNF830 ZNF830 STK39 STK39 TSKU TSKU FA2H FA2H NOD2 NOD2 NR1D1 NR1D1 SLC11A2 SLC11A2 ADCY6 ADCY6 ACP5 ACP5 ACER1 ACER1 STK11 STK11 TRPV1 TRPV1 CNGB1 CNGB1 CDH3 CDH3 TRPV4 TRPV4 ACACB ACACB IRX3 IRX3 COL2A1 COL2A1 AQP6 AQP6 RAB3D RAB3D MKS1 MKS1 ACACA ACACA BBS2 BBS2 TJP3 TJP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EXT2Exostosin-2 isoform X1; Belongs to the glycosyltransferase 47 family. (718 aa)
WFS1Wolframin. (1299 aa)
ADD1Alpha-adducin isoform X1. (773 aa)
CYTL1Cytokine-like protein 1. (153 aa)
SOX9Transcription factor SOX-9. (509 aa)
VSIG1V-set and immunoglobulin domain-containing protein 1. (411 aa)
BBS10Bardet-Biedl syndrome 10 protein. (721 aa)
GATA1Erythroid transcription factor. (413 aa)
IL20RBInterleukin-20 receptor subunit beta isoform X1. (294 aa)
PASKLOW QUALITY PROTEIN: PAS domain-containing serine/threonine-protein kinase. (1426 aa)
TFF3Trefoil factor 3. (80 aa)
TRPM2LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 2. (1514 aa)
CXADRCoxsackievirus and adenovirus receptor isoform X1. (365 aa)
TFF1Trefoil factor 1. (88 aa)
LDB2LIM domain-binding protein 2. (373 aa)
NPHP3Nephrocystin-3. (1330 aa)
SPATA7Spermatogenesis-associated protein 7. (598 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2. (576 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1. (192 aa)
PRLHProlactin-releasing peptide. (87 aa)
PIWIL4Piwi-like protein 4; Belongs to the argonaute family. (860 aa)
NOX4NADPH oxidase 4 isoform X1. (578 aa)
LEPRLeptin receptor. (1166 aa)
SGIP1SH3-containing GRB2-like protein 3-interacting protein 1. (908 aa)
TFF2Trefoil factor 2. (140 aa)
LRRK1Leucine-rich repeat serine/threonine-protein kinase 1. (2014 aa)
PROM1Prominin-1 isoform X1. (848 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (803 aa)
TJP1Tight junction protein ZO-1 isoform X5; Belongs to the MAGUK family. (1770 aa)
CTSHPro-cathepsin H; Belongs to the peptidase C1 family. (335 aa)
CD7T-cell antigen CD7. (209 aa)
RCN3Reticulocalbin-3. (328 aa)
PPP1R13LrelA-associated inhibitor isoform X1. (830 aa)
CRTC3CREB-regulated transcription coactivator 3. (582 aa)
BBS12Bardet-Biedl syndrome 12 protein. (713 aa)
ADRB3Beta-3 adrenergic receptor isoform X1. (399 aa)
KLHL10Kelch-like protein 10. (608 aa)
HOMER2Homer protein homolog 2. (279 aa)
LOC110573247Keratin, type I cytoskeletal 16; Belongs to the intermediate filament family. (465 aa)
SLC39A8Zinc transporter ZIP8. (461 aa)
NDNNecdin. (325 aa)
SH3GL2endophilin-A1. (317 aa)
USH1GUsher syndrome type-1G protein. (461 aa)
NAPSAnapsin-A; Belongs to the peptidase A1 family. (420 aa)
LOC110574021Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (560 aa)
FHFumarate hydratase, mitochondrial isoform X1. (508 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2. (191 aa)
NXNL1Nucleoredoxin-like protein 1. (219 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
KDF1Keratinocyte differentiation factor 1. (397 aa)
CRB1Protein crumbs homolog 1 isoform X1. (1337 aa)
NCDNNeurochondrin. (729 aa)
MFSD2ASodium-dependent lysophosphatidylcholine symporter 1 isoform X1. (529 aa)
MTF1Metal regulatory transcription factor 1. (745 aa)
TMEM79Transmembrane protein 79. (395 aa)
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (279 aa)
LOC110574020Dimethylaniline monooxygenase [N-oxide-forming]. (526 aa)
ILDR2LOW QUALITY PROTEIN: immunoglobulin-like domain-containing receptor 2. (623 aa)
OMA1Metalloendopeptidase OMA1, mitochondrial isoform X1. (525 aa)
CROCCRootletin isoform X1. (1882 aa)
GRHL3Grainyhead-like protein 3 homolog isoform X1. (602 aa)
CD34Hematopoietic progenitor cell antigen CD34 isoform X1. (383 aa)
CRTC1CREB-regulated transcription coactivator 1. (638 aa)
NPHP4Nephrocystin-4. (1396 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
BTBD9BTB/POZ domain-containing protein 9. (612 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (495 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (846 aa)
BBS1Bardet-Biedl syndrome 1 protein. (593 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
TFAP2ETranscription factor AP-2-epsilon. (443 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (457 aa)
TPP1Tripeptidyl-peptidase 1. (572 aa)
USH1CHarmonin. (867 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (546 aa)
MEX3CRNA-binding E3 ubiquitin-protein ligase MEX3C. (636 aa)
AQP4Aquaporin-4 isoform X2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
PRCPLysosomal Pro-X carboxypeptidase isoform X1. (503 aa)
PM20D1N-fatty-acyl-amino acid synthase/hydrolase PM20D1. (503 aa)
PNPLA1Patatin-like phospholipase domain-containing protein 1 isoform X1. (604 aa)
LOC110577685Lysophosphatidylcholine acyltransferase 1-like. (472 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
SASH3SAM and SH3 domain-containing protein 3. (380 aa)
POC1BPOC1 centriolar protein homolog B. (479 aa)
CLRN1Clarin-1. (232 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
TUBTubby-like protein; Belongs to the TUB family. (506 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
CTSKCathepsin K isoform X2; Belongs to the peptidase C1 family. (330 aa)
TNS2Tensin-2 isoform X1. (1408 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A. (652 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
PRDM14PR domain zinc finger protein 14. (571 aa)
XIAPE3 ubiquitin-protein ligase XIAP. (497 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (646 aa)
TP53INP2Tumor protein p53-inducible nuclear protein 2. (221 aa)
PTH1RParathyroid hormone/parathyroid hormone-related peptide receptor; Belongs to the G-protein coupled receptor 2 family. (589 aa)
LOC110577686Lysophosphatidylcholine acyltransferase 1-like. (177 aa)
SRCTyrosine-protein kinase. (536 aa)
RB1Retinoblastoma-associated protein. (934 aa)
SNX10Sorting nexin-10. (201 aa)
LOC110578582Protein S100; Belongs to the S-100 family. (142 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa)
DRAM2DNA damage-regulated autophagy modulator protein 2 isoform X1. (266 aa)
RP1Oxygen-regulated protein 1. (2144 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (159 aa)
ABCA4Retinal-specific ATP-binding cassette transporter. (2270 aa)
LOC110578462LOW QUALITY PROTEIN: filaggrin-2-like. (2068 aa)
KRASGTPase KRas. (188 aa)
IAPPIslet amyloid polypeptide. (89 aa)
HAS2Hyaluronan synthase 2. (552 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (649 aa)
BPIFA1BPI fold-containing family A member 1. (255 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
AQP3Aquaporin-3; Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
UGCGCeramide glucosyltransferase. (394 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
MKKSMcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (570 aa)
CRB2Protein crumbs homolog 2. (1110 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (655 aa)
HOXA13Homeobox protein Hox-A13. (311 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SRFSerum response factor isoform X1. (508 aa)
TFAP2BTranscription factor AP-2-beta isoform X1. (469 aa)
NAPEPLDN-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D. (394 aa)
IL17Ainterleukin-17A. (155 aa)
MUC6Mucin-6. (1301 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SQSTM1Sequestosome-1. (439 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
ILDR1Immunoglobulin-like domain-containing receptor 1. (546 aa)
MUC13Mucin-13. (414 aa)
GPR55G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (320 aa)
LOC110582880GTPase IMAP family member 5-like. (309 aa)
STRAPSerine-threonine kinase receptor-associated protein. (350 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2567 aa)
MRAP2Melanocortin-2 receptor accessory protein 2. (206 aa)
CTGFConnective tissue growth factor. (351 aa)
LRRC45Leucine-rich repeat-containing protein 45. (384 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (309 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
WHRNWhirlin isoform X1. (910 aa)
AQP7Aquaporin-7; Belongs to the MIP/aquaporin (TC 1.A.8) family. (342 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (815 aa)
NOX3NADPH oxidase 3. (566 aa)
SLC35D3Solute carrier family 35 member D3. (417 aa)
BBS4Bardet-Biedl syndrome 4 protein. (521 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1346 aa)
LOC110584033Leucine-rich repeat-containing protein 45-like. (297 aa)
NXNL2Nucleoredoxin-like protein 2. (156 aa)
ALDH1A1Retinal dehydrogenase 1; Belongs to the aldehyde dehydrogenase family. (501 aa)
IQCB1IQ calmodulin-binding motif-containing protein 1 isoform X1. (598 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S-type isoform X1. (663 aa)
AIPL1Aryl-hydrocarbon-interacting protein-like 1. (328 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (587 aa)
CCDC66Coiled-coil domain-containing protein 66 isoform X1. (962 aa)
RHORhodopsin. (348 aa)
TJP2Tight junction protein ZO-2 isoform X2; Belongs to the MAGUK family. (1171 aa)
IL18Interleukin-18 isoform X1. (344 aa)
ACADVLVery long-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1. (690 aa)
FLCNFolliculin isoform X1. (647 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R-type. (699 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
MAKSerine/threonine-protein kinase MAK isoform X1. (649 aa)
BMP6Bone morphogenetic protein 6. (490 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
LOC110584772Toll-like receptor 9 isoform X1. (1328 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (270 aa)
STARD7stAR-related lipid transfer protein 7, mitochondrial. (380 aa)
ALKTyrosine-protein kinase receptor. (1606 aa)
LTKLOW QUALITY PROTEIN: leukocyte tyrosine kinase receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. (834 aa)
AKAP11A-kinase anchor protein 11 isoform X2. (1908 aa)
CCDC154Coiled-coil domain-containing protein 154. (737 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
USH2AUsherin. (5203 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1010 aa)
YAP1Transcriptional coactivator YAP1. (437 aa)
CLCN3Chloride channel protein. (866 aa)
VPS54Vacuolar protein sorting-associated protein 54 isoform X1. (965 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (265 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
LOC110588803Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa)
ADGRV1G-protein coupled receptor 98; Belongs to the G-protein coupled receptor 2 family. (5747 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1573 aa)
CDH23Cadherin-23 isoform X1. (3354 aa)
ERCC6DNA excision repair protein ERCC-6. (1482 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
HOMER1Homer protein homolog 1. (354 aa)
PBLDPhenazine biosynthesis-like domain-containing protein. (288 aa)
NANOS1Nanos homolog 1; Belongs to the nanos family. (280 aa)
CDHR1Cadherin-related family member 1. (859 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
SFTPDPulmonary surfactant-associated protein D. (375 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (591 aa)
SMOSmoothened homolog isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (788 aa)
ARRDC3Arrestin domain-containing protein 3. (414 aa)
EPAS1Endothelial PAS domain-containing protein 1. (865 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1. (746 aa)
LDB1LIM domain-binding protein 1 isoform X1. (411 aa)
VSTM4V-set and transmembrane domain-containing protein 4. (306 aa)
LOC110591485Transmembrane protease serine; Belongs to the peptidase S1 family. (438 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
COL3A1Collagen alpha-1(III) chain. (1464 aa)
LSRLipolysis-stimulated lipoprotein receptor. (579 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
ABCA12ATP-binding cassette sub-family A member 12 isoform X1. (2669 aa)
HNF1AHepatocyte nuclear factor 1-alpha isoform X1. (638 aa)
MLLT6LOW QUALITY PROTEIN: protein AF-17. (1094 aa)
ZNF830Zinc finger protein 830. (371 aa)
STK39STE20/SPS1-related proline-alanine-rich protein kinase. (542 aa)
TSKUTsukushin. (442 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1013 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
SLC11A2Natural resistance-associated macrophage protein 2. (596 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (335 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (278 aa)
STK11Serine/threonine-protein kinase STK11 isoform X1. (596 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (841 aa)
CNGB1Cyclic nucleotide-gated cation channel beta-1. (1194 aa)
CDH3Cadherin-3; Cadherins are calcium-dependent cell adhesion proteins. (828 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (892 aa)
ACACBacetyl-CoA carboxylase 2. (2456 aa)
IRX3Iroquois-class homeodomain protein IRX-3 isoform X1. (502 aa)
COL2A1Collagen alpha-1(II) chain. (1487 aa)
AQP6LOW QUALITY PROTEIN: aquaporin-6; Belongs to the MIP/aquaporin (TC 1.A.8) family. (273 aa)
RAB3DRas-related protein Rab-3D. (219 aa)
MKS1Meckel syndrome type 1 protein. (559 aa)
ACACALOW QUALITY PROTEIN: acetyl-CoA carboxylase 1. (2346 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
TJP3Tight junction protein ZO-3; Belongs to the MAGUK family. (898 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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