STRINGSTRING
BMPR2 BMPR2 BMP4 BMP4 SIX4 SIX4 NOG NOG GATA3 GATA3 EDN1 EDN1 NKX3-1 NKX3-1 BMPR1A BMPR1A PTCH1 PTCH1 PLXNA2 PLXNA2 ECE1 ECE1 EYA1 EYA1 HOXA2 HOXA2 ADGRF5 ADGRF5 TGFBR1 TGFBR1 HES1 HES1 NKX2-6 NKX2-6 EDNRA EDNRA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (944 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (456 aa)
SIX4Homeobox protein SIX4. (785 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
EDN1Endothelin-1. (202 aa)
NKX3-1Homeobox protein Nkx-3.1 isoform X1. (231 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PTCH1Protein patched homolog 1. (1301 aa)
PLXNA2plexin-A2. (1894 aa)
ECE1Endothelin-converting enzyme 1 isoform X1. (767 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
HOXA2Homeobox protein Hox-A2. (374 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1346 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
HES1Transcription factor HES-1. (280 aa)
NKX2-6Homeobox protein Nkx-2.6. (302 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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