STRINGSTRING
NOG NOG TBX2 TBX2 WNT11 WNT11 TMEM100 TMEM100 ACVRL1 ACVRL1 HNF1A HNF1A FOXF1 FOXF1 BMPR1A BMPR1A TBX20 TBX20 ACTG2 ACTG2 TBX3 TBX3 OSR1 OSR1 ACTC1 ACTC1 ACTA2 ACTA2 SMAD3 SMAD3 ACTA1 ACTA1 NOTCH1 NOTCH1 EXOC4 EXOC4 ENG ENG BMP2 BMP2 SNAI1 SNAI1 TAF10 TAF10 SMAD4 SMAD4 LEF1 LEF1 LOC110576215 LOC110576215 APLNR APLNR MDM2 MDM2 SOX9 SOX9 GATA5 GATA5 MSX1 MSX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TBX2T-box transcription factor TBX2. (713 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TMEM100Transmembrane protein 100. (134 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
HNF1AHepatocyte nuclear factor 1-alpha isoform X1. (638 aa)
FOXF1Forkhead box protein F1. (384 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TBX20T-box transcription factor TBX20. (447 aa)
ACTG2Actin, gamma-enteric smooth muscle. (376 aa)
TBX3T-box transcription factor TBX3. (727 aa)
OSR1Protein odd-skipped-related 1. (267 aa)
ACTC1Actin, alpha cardiac muscle 1 isoform X1. (377 aa)
ACTA2Actin, aortic smooth muscle. (377 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ACTA1Actin, alpha skeletal muscle. (377 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2567 aa)
EXOC4Exocyst complex component 4 isoform X1. (975 aa)
ENGEndoglin. (650 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
SNAI1Zinc finger protein SNAI1. (264 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
LOC110576215Actin, alpha skeletal muscle 2-like. (436 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
SOX9Transcription factor SOX-9. (509 aa)
GATA5Transcription factor GATA-5. (404 aa)
MSX1Homeobox protein MSX-1. (303 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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