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MAPK1 MAPK1 MAPK11 MAPK11 MASTL MASTL STK4 STK4 CSNK2A1 CSNK2A1 MAPKAPK3 MAPKAPK3 PRKCB PRKCB MAPK15 MAPK15 MAP3K12 MAP3K12 PRKDC PRKDC FBXW12 FBXW12 RIPK2 RIPK2 DSTYK DSTYK MAPK12 MAPK12 PIM3 PIM3 CDK4 CDK4 CDK2 CDK2 PLK1 PLK1 PAK3 PAK3 MAP3K8 MAP3K8 CAMK2D CAMK2D MAP3K11 MAP3K11 RPS6KA4 RPS6KA4 ROCK1 ROCK1 PINK1 PINK1 RIOK3 RIOK3 MKNK1 MKNK1 STK33 STK33 MTOR MTOR MAP4K2 MAP4K2 RPS6KB2 RPS6KB2 MAPK14 MAPK14 PRKCZ PRKCZ MAP2K1 MAP2K1 MAPK7 MAPK7 PAK2 PAK2 AURKB AURKB PRKCD PRKCD TNK2 TNK2 RAF1 RAF1 CDK5 CDK5 LOC110585707 LOC110585707 LOC110583655 LOC110583655 CSNK1G1 CSNK1G1 MAP3K21 MAP3K21 ANKK1 ANKK1 PRKCQ PRKCQ SBK1 SBK1 CAMK2A CAMK2A PRKD1 PRKD1 ROCK2 ROCK2 MAP4K3 MAP4K3 STK10 STK10 PRKG1 PRKG1 PRPF4B PRPF4B RIOK1 RIOK1 LOC110588744 LOC110588744 CDK1 CDK1 CAMK2G CAMK2G MAPK8 MAPK8 TMEM248 TMEM248 MAPK3 MAPK3 DCLK2 DCLK2 MAP4K1 MAP4K1 PRKCE PRKCE PRKCH PRKCH MAP4K5 MAP4K5 AAK1 AAK1 LOC110591391 LOC110591391 PRKG2 PRKG2 LOC110591392 LOC110591392 MAP3K10 MAP3K10 PAK4 PAK4 AKT2 AKT2 CIT CIT PSKH2 PSKH2 PAK5 PAK5 TSSK1B TSSK1B TESK1 TESK1 TTBK1 TTBK1 PIK3CA PIK3CA MAP3K13 MAP3K13 GSK3B GSK3B PRKACB PRKACB RPS6KA2 RPS6KA2 LOC110583232 LOC110583232 CDK9 CDK9 RPS6KA6 RPS6KA6 MAP3K7 MAP3K7 MELK MELK CLK3 CLK3 CCDC151 CCDC151 CSNK2A2 CSNK2A2 CDK10 CDK10 CDK12 CDK12 PKN1 PKN1 CDK13 CDK13 PRKACA PRKACA RPS6KB1 RPS6KB1 PSKH1 PSKH1 LOC110592452 LOC110592452 MAP2K2 MAP2K2 IRAK4 IRAK4 PAK1 PAK1 HASPIN HASPIN PRKCI PRKCI NLK NLK CAMK2B CAMK2B VSIG10 VSIG10 LIMK2 LIMK2 PIM1 PIM1 PCK1 PCK1 AURKA AURKA DCLK1 DCLK1 MAP2K6 MAP2K6 LOC110569630 LOC110569630 PRKCA PRKCA RPS6KA5 RPS6KA5 NEK10 NEK10 VRK1 VRK1 PIK3CB PIK3CB MAP3K9 MAP3K9 PIM2 PIM2 STK25 STK25 AKT1 AKT1 PLK4 PLK4 IKBKB IKBKB CNTD1 CNTD1 RPS6KA3 RPS6KA3 SBK3 SBK3 AKT3 AKT3 PIK3CG PIK3CG PRKD2 PRKD2 IRAK1 IRAK1 PRKCG PRKCG PRKAA2 PRKAA2 RPS6KA1 RPS6KA1 STK40 STK40 STK26 STK26 MAPK13 MAPK13 MAPK9 MAPK9 LOC110577953 LOC110577953
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
MASTLSerine/threonine-protein kinase greatwall isoform X3. (886 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (398 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (384 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
MAPK15Mitogen-activated protein kinase 15. (703 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
PRKDCDNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (4135 aa)
FBXW12F-box/WD repeat-containing protein 12. (465 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (929 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
PIM3Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (322 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
CDK2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
PAK3Non-specific serine/threonine protein kinase. (544 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4. (525 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase 11 isoform X1. (947 aa)
RPS6KA4Ribosomal protein S6 kinase. (772 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial isoform X1. (583 aa)
RIOK3Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (519 aa)
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (418 aa)
STK33Serine/threonine-protein kinase 33 isoform X1. (521 aa)
MTORSerine/threonine-protein kinase mTOR. (2557 aa)
MAP4K2Mitogen-activated protein kinase kinase kinase kinase 2. (489 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (483 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
AURKBAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (344 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
TNK2Activated CDC42 kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1057 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
LOC110585707LOW QUALITY PROTEIN: aurora kinase A-like. (266 aa)
LOC110583655LOW QUALITY PROTEIN: serine/threonine-protein kinase Sgk1-like. (445 aa)
CSNK1G1Casein kinase I; Belongs to the protein kinase superfamily. (459 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase. (1057 aa)
ANKK1LOW QUALITY PROTEIN: ankyrin repeat and protein kinase domain-containing protein 1. (678 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
SBK1Serine/threonine-protein kinase SBK1. (312 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (489 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1391 aa)
MAP4K3Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (906 aa)
STK10Serine/threonine-protein kinase 10. (967 aa)
PRKG1cGMP-dependent protein kinase. (726 aa)
PRPF4BSerine/threonine-protein kinase PRP4 homolog. (1041 aa)
RIOK1Serine/threonine-protein kinase RIO1. (464 aa)
LOC110588744Uncharacterized protein FLJ45252-like. (337 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (606 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
TMEM248Transmembrane protein 248 isoform X1. (314 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
DCLK2Serine/threonine-protein kinase DCLK2 isoform X1. (783 aa)
MAP4K1Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
PRKCHProtein kinase C. (710 aa)
MAP4K5Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (846 aa)
AAK1AP2-associated protein kinase 1. (959 aa)
LOC110591391Mitogen-activated protein kinase 10-like. (176 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
LOC110591392Mitogen-activated protein kinase. (300 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (934 aa)
PAK4Non-specific serine/threonine protein kinase. (594 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
PSKH2Serine/threonine-protein kinase H2; Belongs to the protein kinase superfamily. (385 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
TSSK1BTestis-specific serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (367 aa)
TESK1Dual specificity testis-specific protein kinase 1. (628 aa)
TTBK1LOW QUALITY PROTEIN: tau-tubulin kinase 1. (1326 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
RPS6KA2Ribosomal protein S6 kinase. (727 aa)
LOC110583232Uncharacterized protein LOC110583232. (149 aa)
CDK9Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
RPS6KA6Ribosomal protein S6 kinase. (744 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
MELKNon-specific serine/threonine protein kinase. (651 aa)
CLK3Dual specificity protein kinase CLK3 isoform X2. (587 aa)
CCDC151Coiled-coil domain-containing protein 151 isoform X1. (596 aa)
CSNK2A2Casein kinase II subunit alpha. (213 aa)
CDK10Cyclin-dependent kinase 10 isoform X1. (373 aa)
CDK12Cyclin-dependent kinase 12 isoform X1. (1491 aa)
PKN1Serine/threonine-protein kinase N1 isoform X1. (950 aa)
CDK13Cyclin-dependent kinase 13 isoform X1. (1514 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
PSKH1Serine/threonine-protein kinase H1; Belongs to the protein kinase superfamily. (424 aa)
LOC110592452Serine/threonine-protein kinase TAO3-like. (104 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
IRAK4Interleukin-1 receptor-associated kinase 4. (460 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
HASPINSerine/threonine-protein kinase haspin. (770 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
NLKSerine/threonine-protein kinase NLK. (306 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta. (651 aa)
VSIG10V-set and immunoglobulin domain-containing protein 10. (408 aa)
LIMK2LIM domain kinase 2 isoform X1. (631 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (320 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1. (622 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
DCLK1Serine/threonine-protein kinase DCLK1 isoform X1. (740 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
LOC110569630Serine/threonine-protein kinase ULK4-like. (444 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
RPS6KA5Ribosomal protein S6 kinase. (798 aa)
NEK10Serine/threonine-protein kinase Nek10. (1154 aa)
VRK1Serine/threonine-protein kinase VRK1 isoform X1; Belongs to the protein kinase superfamily. (395 aa)
PIK3CBLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase. (1102 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (311 aa)
STK25Serine/threonine-protein kinase 25. (426 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PLK4Serine/threonine-protein kinase PLK4. (970 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
CNTD1Cyclin N-terminal domain-containing protein 1. (329 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
SBK3Uncharacterized serine/threonine-protein kinase SBK3; Belongs to the protein kinase superfamily. (362 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1102 aa)
PRKD2Serine/threonine-protein kinase D2. (725 aa)
IRAK1Interleukin-1 receptor-associated kinase 1. (726 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
STK40Serine/threonine-protein kinase 40 isoform X1. (440 aa)
STK26Serine/threonine-protein kinase 26 isoform X1. (416 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
LOC110577953Mitogen-activated protein kinase kinase kinase kinase 2-like. (341 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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