35 items (Neomonachus schauinslandi) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RNF34	E3 ubiquitin-protein ligase RNF34. (375 aa)
	FAIM	Fas apoptotic inhibitory molecule 1. (179 aa)
	BMPR1B	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	SFRP1	Secreted frizzled-related protein 1. (314 aa)
	PEA15	Astrocytic phosphoprotein PEA-15. (130 aa)
	DDX3X	ATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
	TMC8	Transmembrane channel-like protein. (723 aa)
	ARHGEF2	Rho guanine nucleotide exchange factor 2 isoform X1. (964 aa)
	ATF3	Cyclic AMP-dependent transcription factor ATF-3. (181 aa)
	PARK7	LOW QUALITY PROTEIN: protein DJ-1-like. (189 aa)
	MADD	MAP kinase-activating death domain protein isoform X1. (1588 aa)
	TIMP3	Metalloproteinase inhibitor 3. (211 aa)
	PMAIP1	Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
	STK3	Serine/threonine-protein kinase 3. (491 aa)
	STK4	Serine/threonine-protein kinase 4. (487 aa)
	HMOX1	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
	TMBIM7P	Protein lifeguard 2; Belongs to the BI1 family. (301 aa)
	LOC110581163	ATP-dependent RNA helicase DDX3X-like; Belongs to the DEAD box helicase family. (662 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
	GSK3B	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
	TNFAIP3	Tumor necrosis factor alpha-induced protein 3 isoform X1. (795 aa)
	RAF1	RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
	THBS1	Thrombospondin-1. (1170 aa)
	FEM1B	Protein fem-1 homolog B. (627 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	SFRP2	Secreted frizzled-related protein 2. (294 aa)
	ITPRIP	Inositol 1,4,5-trisphosphate receptor-interacting protein isoform X2. (552 aa)
	ITPRIPL2	Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2. (532 aa)
	SKIL	Ski-like protein isoform X1. (684 aa)
	LGALS3	Galectin. (285 aa)
	ZSWIM2	E3 ubiquitin-protein ligase ZSWIM2. (636 aa)
	TMBIM1	Protein lifeguard 3 isoform X1; Belongs to the BI1 family. (308 aa)
	CFLAR	CASP8 and FADD-like apoptosis regulator; Belongs to the peptidase C14A family. (482 aa)
	RFFL	E3 ubiquitin-protein ligase rififylin. (358 aa)
	FAIM2	Protein lifeguard 2 isoform X1; Belongs to the BI1 family. (315 aa)

Your Current Organism:

Neomonachus schauinslandi

NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF3	GSK3B	A0A2Y9GLF3	A0A2Y9H9J4	Cyclic AMP-dependent transcription factor ATF-3.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.564
ATF3	TNFAIP3	A0A2Y9GLF3	A0A2Y9HAQ7	Cyclic AMP-dependent transcription factor ATF-3.	Tumor necrosis factor alpha-induced protein 3 isoform X1.	0.418
FEM1B	PMAIP1	A0A2Y9HJG0	A0A2Y9GXQ0	Protein fem-1 homolog B.	Phorbol-12-myristate-13-acetate-induced protein 1.	0.473
GSK3B	ATF3	A0A2Y9H9J4	A0A2Y9GLF3	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	Cyclic AMP-dependent transcription factor ATF-3.	0.564
GSK3B	HMOX1	A0A2Y9H9J4	A0A2Y9GZS8	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	0.489
GSK3B	PTEN	A0A2Y9H9J4	A0A2Y9HQC2	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.657
GSK3B	RAF1	A0A2Y9H9J4	A0A2Y9HGE7	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	RAF proto-oncogene serine/threonine-protein kinase.	0.912
GSK3B	SFRP1	A0A2Y9H9J4	A0A2Y9GDP6	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	Secreted frizzled-related protein 1.	0.591
GSK3B	SFRP2	A0A2Y9H9J4	A0A2Y9HSB3	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	Secreted frizzled-related protein 2.	0.428
HMOX1	GSK3B	A0A2Y9GZS8	A0A2Y9H9J4	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.489
PARK7	PTEN	A0A2Y9GMD9	A0A2Y9HQC2	LOW QUALITY PROTEIN: protein DJ-1-like.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.605
PMAIP1	FEM1B	A0A2Y9GXQ0	A0A2Y9HJG0	Phorbol-12-myristate-13-acetate-induced protein 1.	Protein fem-1 homolog B.	0.473
PTEN	GSK3B	A0A2Y9HQC2	A0A2Y9H9J4	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.657
PTEN	PARK7	A0A2Y9HQC2	A0A2Y9GMD9	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	LOW QUALITY PROTEIN: protein DJ-1-like.	0.605
PTEN	RAF1	A0A2Y9HQC2	A0A2Y9HGE7	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	RAF proto-oncogene serine/threonine-protein kinase.	0.532
PTEN	TIMP3	A0A2Y9HQC2	A0A2Y9GUZ3	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	Metalloproteinase inhibitor 3.	0.473
RAF1	GSK3B	A0A2Y9HGE7	A0A2Y9H9J4	RAF proto-oncogene serine/threonine-protein kinase.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.912
RAF1	PTEN	A0A2Y9HGE7	A0A2Y9HQC2	RAF proto-oncogene serine/threonine-protein kinase.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.532
SFRP1	GSK3B	A0A2Y9GDP6	A0A2Y9H9J4	Secreted frizzled-related protein 1.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.591
SFRP1	SFRP2	A0A2Y9GDP6	A0A2Y9HSB3	Secreted frizzled-related protein 1.	Secreted frizzled-related protein 2.	0.800