STRINGSTRING
LOC110577505 LOC110577505 UBA52 UBA52 STMN1 STMN1 EGF EGF NCSTN NCSTN SHC1 SHC1 LOC110573272 LOC110573272 GRB2 GRB2 GFAP GFAP KRAS KRAS LOC110579526 LOC110579526 FNDC3A FNDC3A ITCH ITCH NRAS NRAS HRAS HRAS PIK3CA PIK3CA ESR1 ESR1 NRG1 NRG1 NEDD4 NEDD4 APH1B APH1B NRG4 NRG4 LOC110586377 LOC110586377 LOC110588252 LOC110588252 CSDE1 CSDE1 PSEN2 PSEN2 SRC SRC YAP1 YAP1 LOC110588689 LOC110588689 SOS1 SOS1 PSENEN PSENEN RPS27A RPS27A NRG3 NRG3 ERAS ERAS PSEN1 PSEN1 LOC110572955 LOC110572955 ADAP1 ADAP1 HBEGF HBEGF NRG2 NRG2 PIK3R1 PIK3R1 CSN2 CSN2 EREG EREG BTC BTC ERBB4 ERBB4 EGFR EGFR FNDC3B FNDC3B WWOX WWOX ADAP2 ADAP2 ERBB3 ERBB3 WWP1 WWP1 APH1A APH1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC110577505Max dimerization protein 4-like. (128 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
STMN1Stathmin; Belongs to the stathmin family. (149 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1197 aa)
NCSTNNicastrin. (709 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
LOC110573272Signal transducer and activator of transcription 5A. (478 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
GFAPGlial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family. (432 aa)
KRASGTPase KRas. (188 aa)
LOC110579526Signal transducer and activator of transcription 5A-like. (153 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1199 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
NRASGTPase NRas. (189 aa)
HRASGTPase HRas isoform X1. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X1. (857 aa)
NEDD4E3 ubiquitin-protein ligase NEDD4 isoform X1. (1323 aa)
APH1BGamma-secretase subunit APH-1B isoform X1. (257 aa)
NRG4Pro-neuregulin-4, membrane-bound isoform. (126 aa)
LOC110586377ubiquitin-60S ribosomal protein L40-like. (162 aa)
LOC110588252Ubiquitin. (77 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
SRCTyrosine-protein kinase. (536 aa)
YAP1Transcriptional coactivator YAP1. (437 aa)
LOC110588689ubiquitin-40S ribosomal protein S27a-like. (154 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
PSENENGamma-secretase subunit PEN-2. (101 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform. (674 aa)
ERASGTPase ERas. (233 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
LOC110572955Fibronectin type III domain containing protein 3C1-like. (1437 aa)
ADAP1arf-GAP with dual PH domain-containing protein 1 isoform X1. (374 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
NRG2Pro-neuregulin-2, membrane-bound isoform isoform X2. (853 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
CSN2Beta-casein. (259 aa)
EREGProepiregulin. (308 aa)
BTCProbetacellulin. (178 aa)
ERBB4Receptor protein-tyrosine kinase. (1270 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1208 aa)
WWOXWW domain-containing oxidoreductase. (414 aa)
ADAP2arf-GAP with dual PH domain-containing protein 2. (385 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
WWP1E3 ubiquitin-protein ligase. (921 aa)
APH1AGamma-secretase subunit APH-1A. (265 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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