49 items (Neomonachus schauinslandi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC110572955	Fibronectin type III domain containing protein 3C1-like. (1437 aa)
	PTK6	Tyrosine-protein kinase. (486 aa)
	SRMS	Tyrosine-protein kinase. (493 aa)
	ERAS	GTPase ERas. (233 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1208 aa)
	GAB2	GRB2-associated-binding protein 2. (678 aa)
	GRB10	Growth factor receptor-bound protein 10. (643 aa)
	STAT1	Signal transducer and activator of transcription. (750 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
	TEC	Tyrosine-protein kinase. (630 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (823 aa)
	SH2B2	SH2B adapter protein 2. (937 aa)
	SOS1	Son of sevenless homolog 1. (1333 aa)
	SH2B3	SH2B adapter protein 3. (578 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
	CHEK1	Serine/threonine-protein kinase Chk1 isoform X1; Belongs to the protein kinase superfamily. (476 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (910 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	GRAP	GRB2-related adapter protein. (217 aa)
	JAK2	Tyrosine-protein kinase. (1130 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	NRAS	GTPase NRas. (189 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A. (1199 aa)
	LOC110579526	Signal transducer and activator of transcription 5A-like. (153 aa)
	KRAS	GTPase KRas. (188 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	LOC110579958	Signal transducer and activator of transcription 5B-like. (204 aa)
	SRC	Tyrosine-protein kinase. (536 aa)
	MMP9	Matrix metalloproteinase-9 isoform X1. (704 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	GRAP2	GRB2-related adapter protein 2. (316 aa)
	KITLG	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
	PTPRU	Receptor-type tyrosine-protein phosphatase U. (1436 aa)
	LOC110575329	Tyrosine-protein phosphatase non-receptor type 11-like. (582 aa)
	STAT3	Signal transducer and activator of transcription. (770 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
	LOC110573272	Signal transducer and activator of transcription 5A. (478 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (820 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	LOC110573273	Signal transducer and activator of transcription 5B. (600 aa)
	ELSPBP1	Epididymal sperm-binding protein 1. (223 aa)
	VAV1	Proto-oncogene vav isoform X1. (845 aa)
	GRB7	Growth factor receptor-bound protein 7. (530 aa)

Your Current Organism:

Neomonachus schauinslandi

NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBL	FYN	A0A2Y9HQP6	A0A2Y9HIT8	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.821
CBL	GRAP	A0A2Y9HQP6	A0A2Y9HFA0	E3 ubiquitin-protein ligase CBL.	GRB2-related adapter protein.	0.826
CBL	GRAP2	A0A2Y9HQP6	A0A2Y9GVU9	E3 ubiquitin-protein ligase CBL.	GRB2-related adapter protein 2.	0.761
CBL	GRB2	A0A2Y9HQP6	A0A2Y9GF83	E3 ubiquitin-protein ligase CBL.	Growth factor receptor-bound protein 2.	0.999
CBL	JAK2	A0A2Y9HQP6	A0A2Y9HEH0	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.612
CBL	KIT	A0A2Y9HQP6	A0A2Y9I0C6	E3 ubiquitin-protein ligase CBL.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.735
CBL	KITLG	A0A2Y9HQP6	A0A2Y9GVF7	E3 ubiquitin-protein ligase CBL.	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.	0.534
CBL	LOC110575329	A0A2Y9HQP6	A0A2Y9GLM7	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein phosphatase non-receptor type 11-like.	0.623
CBL	LYN	A0A2Y9HQP6	A0A2Y9GY53	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.950
CBL	PIK3CA	A0A2Y9HQP6	A0A2Y9H8I3	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.865
CBL	PIK3R1	A0A2Y9HQP6	A0A2Y9I1U1	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.989
CBL	PIK3R2	A0A2Y9HQP6	A0A2Y9GIN4	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1.	0.929
CBL	PIK3R3	A0A2Y9HQP6	A0A2Y9GQC6	E3 ubiquitin-protein ligase CBL.	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1.	0.896
CBL	PTK6	A0A2Y9HQP6	A0A2Y9G5Q7	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.821
CBL	PTPN11	A0A2Y9HQP6	A0A2Y9HQZ9	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.719
CBL	PTPN6	A0A2Y9HQP6	A0A2Y9H8M8	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.434
CBL	SH2B2	A0A2Y9HQP6	A0A2Y9HX15	E3 ubiquitin-protein ligase CBL.	SH2B adapter protein 2.	0.943
CBL	SH2B3	A0A2Y9HQP6	A0A2Y9HRC8	E3 ubiquitin-protein ligase CBL.	SH2B adapter protein 3.	0.610
CBL	SOS1	A0A2Y9HQP6	A0A2Y9HT35	E3 ubiquitin-protein ligase CBL.	Son of sevenless homolog 1.	0.593
CBL	SRC	A0A2Y9HQP6	A0A2Y9H031	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.901