STRINGSTRING
RALB RALB SOS1 SOS1 MAPK3 MAPK3 RALA RALA MAP2K2 MAP2K2 MAPK1 MAPK1 SHC2 SHC2 CRK CRK BRAF BRAF MAPK11 MAPK11 YWHAB YWHAB MAPKAPK3 MAPKAPK3 CRKL CRKL RIT2 RIT2 MAPK14 MAPK14 MAPKAPK2 MAPKAPK2 RIT1 RIT1 NTRK1 NTRK1 SHC1 SHC1 NKPD1 NKPD1 GRB2 GRB2 ERAS ERAS FRS2 FRS2 RAPGEF1 RAPGEF1 SHC4 SHC4 MAP2K1 MAP2K1 SHC3 SHC3 KIDINS220 KIDINS220 HRAS HRAS NRAS NRAS RALGDS RALGDS KRAS KRAS RAP1A RAP1A NGF NGF CSDE1 CSDE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RALBRas-related protein Ral-B. (206 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
RALARas-related protein Ral-A. (206 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
SHC2SHC-transforming protein 2. (551 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
BRAFSerine/threonine-protein kinase B-raf. (764 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (384 aa)
CRKLCrk-like protein. (303 aa)
RIT2GTP-binding protein Rit2 isoform X1. (217 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPKAPK2MAP kinase-activated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (402 aa)
RIT1GTP-binding protein Rit1. (219 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
NKPD1NTPase KAP family P-loop domain-containing protein 1 isoform X1. (822 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
ERASGTPase ERas. (233 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1025 aa)
SHC4SHC-transforming protein 4. (630 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
SHC3SHC-transforming protein 3. (469 aa)
KIDINS220Kinase D-interacting substrate of 220 kDa. (1754 aa)
HRASGTPase HRas isoform X1. (189 aa)
NRASGTPase NRas. (189 aa)
RALGDSRal guanine nucleotide dissociation stimulator isoform X1. (886 aa)
KRASGTPase KRas. (188 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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