33 items (Neomonachus schauinslandi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LCP2	Lymphocyte cytosolic protein 2. (533 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1289 aa)
	SIGLEC15	Sialic acid-binding Ig-like lectin 15. (329 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	PTK6	Tyrosine-protein kinase. (486 aa)
	SRMS	Tyrosine-protein kinase. (493 aa)
	ERAS	GTPase ERas. (233 aa)
	PIK3CB	LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (584 aa)
	GRAP2	GRB2-related adapter protein 2. (316 aa)
	VAV3	Guanine nucleotide exchange factor VAV3. (847 aa)
	LOC110580780	NKG2-D type II integral membrane protein. (216 aa)
	KLRD1	Natural killer cells antigen CD94. (248 aa)
	KRAS	GTPase KRas. (188 aa)
	KLRG1	Killer cell lectin-like receptor subfamily G member 1. (189 aa)
	NRAS	GTPase NRas. (189 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2. (230 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	TREML1	Trem-like transcript 1 protein. (312 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	VAV2	Guanine nucleotide exchange factor VAV2. (862 aa)
	SPNS3	Protein spinster homolog 3. (380 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	SYK	Tyrosine-protein kinase. (635 aa)
	BTK	Tyrosine-protein kinase. (659 aa)
	SOS1	Son of sevenless homolog 1. (1333 aa)
	SPNS1	Protein spinster homolog 1 isoform X1. (528 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1200 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
	TYROBP	TYRO protein tyrosine kinase-binding protein isoform X1. (111 aa)
	LAT	Linker for activation of T-cells family member 1. (256 aa)

Your Current Organism:

Neomonachus schauinslandi

NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTK	GRAP2	A0A2Y9HPA0	A0A2Y9GVU9	Tyrosine-protein kinase.	GRB2-related adapter protein 2.	0.732
BTK	GRB2	A0A2Y9HPA0	A0A2Y9GF83	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2.	0.809
BTK	LAT	A0A2Y9HPA0	A0A2Y9HX23	Tyrosine-protein kinase.	Linker for activation of T-cells family member 1.	0.529
BTK	LCP2	A0A2Y9HPA0	A0A2Y9HWW5	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2.	0.966
BTK	PIK3CA	A0A2Y9HPA0	A0A2Y9H8I3	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.946
BTK	PIK3CB	A0A2Y9HPA0	A0A2Y9G8Q1	Tyrosine-protein kinase.	LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family.	0.936
BTK	PIK3R1	A0A2Y9HPA0	A0A2Y9I1U1	Tyrosine-protein kinase.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.936
BTK	PIK3R2	A0A2Y9HPA0	A0A2Y9GIN4	Tyrosine-protein kinase.	Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1.	0.913
BTK	PLCG1	A0A2Y9HPA0	A0A2Y9GZB7	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.957
BTK	PLCG2	A0A2Y9HPA0	A0A2Y9IHT4	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.987
BTK	SHC1	A0A2Y9HPA0	A0A2Y9GIP3	Tyrosine-protein kinase.	SHC-transforming protein 1 isoform X1.	0.620
BTK	SOS1	A0A2Y9HPA0	A0A2Y9HT35	Tyrosine-protein kinase.	Son of sevenless homolog 1.	0.503
BTK	SYK	A0A2Y9HPA0	A0A2Y9HKC1	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.969
BTK	TYROBP	A0A2Y9HPA0	A0A2Y9HYC9	Tyrosine-protein kinase.	TYRO protein tyrosine kinase-binding protein isoform X1.	0.485
BTK	VAV2	A0A2Y9HPA0	A0A2Y9HBW0	Tyrosine-protein kinase.	Guanine nucleotide exchange factor VAV2.	0.727
BTK	VAV3	A0A2Y9HPA0	A0A2Y9H318	Tyrosine-protein kinase.	Guanine nucleotide exchange factor VAV3.	0.694
CSDE1	GRB2	A0A2Y9H2J4	A0A2Y9GF83	Cold shock domain-containing protein E1 isoform X1.	Growth factor receptor-bound protein 2.	0.591
CSDE1	PIK3CA	A0A2Y9H2J4	A0A2Y9H8I3	Cold shock domain-containing protein E1 isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.709
CSDE1	PIK3CB	A0A2Y9H2J4	A0A2Y9G8Q1	Cold shock domain-containing protein E1 isoform X1.	LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family.	0.518
CSDE1	PIK3R1	A0A2Y9H2J4	A0A2Y9I1U1	Cold shock domain-containing protein E1 isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.516