11 items (Neomonachus schauinslandi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	ERAS	GTPase ERas. (233 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	KRAS	GTPase KRas. (188 aa)
	NRAS	GTPase NRas. (189 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	LOC110586166	Stromelysin-1. (476 aa)
	SOS1	Son of sevenless homolog 1. (1333 aa)
	EGFR	Receptor protein-tyrosine kinase. (1207 aa)

Your Current Organism:

Neomonachus schauinslandi

NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	EGFR	A0A2Y9H2J4	A0A2Y9I6V3	Cold shock domain-containing protein E1 isoform X1.	Receptor protein-tyrosine kinase.	0.456
CSDE1	GRB2	A0A2Y9H2J4	A0A2Y9GF83	Cold shock domain-containing protein E1 isoform X1.	Growth factor receptor-bound protein 2.	0.591
CSDE1	SOS1	A0A2Y9H2J4	A0A2Y9HT35	Cold shock domain-containing protein E1 isoform X1.	Son of sevenless homolog 1.	0.634
EGFR	CSDE1	A0A2Y9I6V3	A0A2Y9H2J4	Receptor protein-tyrosine kinase.	Cold shock domain-containing protein E1 isoform X1.	0.456
EGFR	ERAS	A0A2Y9I6V3	A0A2Y9G6Q7	Receptor protein-tyrosine kinase.	GTPase ERas.	0.570
EGFR	GRB2	A0A2Y9I6V3	A0A2Y9GF83	Receptor protein-tyrosine kinase.	Growth factor receptor-bound protein 2.	0.999
EGFR	HBEGF	A0A2Y9I6V3	A0A2Y9I0U7	Receptor protein-tyrosine kinase.	Proheparin-binding EGF-like growth factor.	0.996
EGFR	HRAS	A0A2Y9I6V3	A0A2Y9H803	Receptor protein-tyrosine kinase.	GTPase HRas isoform X1.	0.935
EGFR	KRAS	A0A2Y9I6V3	A0A2Y9H3K4	Receptor protein-tyrosine kinase.	GTPase KRas.	0.967
EGFR	NRAS	A0A2Y9I6V3	A0A2Y9H767	Receptor protein-tyrosine kinase.	GTPase NRas.	0.935
EGFR	PRKCA	A0A2Y9I6V3	A0A2Y9G7H4	Receptor protein-tyrosine kinase.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.501
EGFR	SOS1	A0A2Y9I6V3	A0A2Y9HT35	Receptor protein-tyrosine kinase.	Son of sevenless homolog 1.	0.996
ERAS	EGFR	A0A2Y9G6Q7	A0A2Y9I6V3	GTPase ERas.	Receptor protein-tyrosine kinase.	0.570
ERAS	GRB2	A0A2Y9G6Q7	A0A2Y9GF83	GTPase ERas.	Growth factor receptor-bound protein 2.	0.591
ERAS	SOS1	A0A2Y9G6Q7	A0A2Y9HT35	GTPase ERas.	Son of sevenless homolog 1.	0.671
GRB2	CSDE1	A0A2Y9GF83	A0A2Y9H2J4	Growth factor receptor-bound protein 2.	Cold shock domain-containing protein E1 isoform X1.	0.591
GRB2	EGFR	A0A2Y9GF83	A0A2Y9I6V3	Growth factor receptor-bound protein 2.	Receptor protein-tyrosine kinase.	0.999
GRB2	ERAS	A0A2Y9GF83	A0A2Y9G6Q7	Growth factor receptor-bound protein 2.	GTPase ERas.	0.591
GRB2	HBEGF	A0A2Y9GF83	A0A2Y9I0U7	Growth factor receptor-bound protein 2.	Proheparin-binding EGF-like growth factor.	0.505
GRB2	HRAS	A0A2Y9GF83	A0A2Y9H803	Growth factor receptor-bound protein 2.	GTPase HRas isoform X1.	0.591