STRINGSTRING
PSMD13 PSMD13 HRAS HRAS BCL10 BCL10 NRAS NRAS PPP3R2 PPP3R2 KRAS KRAS VAV3 VAV3 CSDE1 CSDE1 TAB3 TAB3 PAK1 PAK1 PSMB10 PSMB10 NFAT5 NFAT5 MAP3K20 MAP3K20 NFATC3 NFATC3 PSMD3 PSMD3 PSMB3 PSMB3 PSMD11 PSMD11 LOC110592969 LOC110592969 MAP2K7 MAP2K7 PLCG2 PLCG2 VAV1 VAV1 PSMF1 PSMF1 PLCG1 PLCG1 UBE2N UBE2N LOC110577584 LOC110577584 MAPK1 MAPK1 TAB1 TAB1 PSMC2 PSMC2 CLNK CLNK PSMD12 PSMD12 PSMC5 PSMC5 PSMA7 PSMA7 ERAS ERAS PSMD10 PSMD10 FOS FOS PIK3CB PIK3CB PSMC1 PSMC1 CALM1 CALM1 PPP3CA PPP3CA PSMA4 PSMA4 NFKB1 NFKB1 IKBKB IKBKB LOC110573367 LOC110573367 FCER1A FCER1A LOC110573363 LOC110573363 GRB2 GRB2 LOC110574051 LOC110574051 IKBKG IKBKG PSME3 PSME3 FCRL2 FCRL2 PIK3R2 PIK3R2 SHC1 SHC1 LOC110573364 LOC110573364 FCER1G FCER1G JUN JUN CCDC71L CCDC71L KXD1 KXD1 PSMB9 PSMB9 LOC110574299 LOC110574299 MS4A2 MS4A2 MS4A1 MS4A1 PSMB2 PSMB2 RELA RELA UBA52 UBA52 PSMA1 PSMA1 NFATC2 NFATC2 PSMB8 PSMB8 UBE2V1 UBE2V1 PSMC3 PSMC3 MALT1 MALT1 LOC110575869 LOC110575869 LOC110575868 LOC110575868 MAPK9 MAPK9 MS4A4A MS4A4A LOC110576171 LOC110576171 TRAF6 TRAF6 HARBI1 HARBI1 NFATC1 NFATC1 PSMA8 PSMA8 GRAP2 GRAP2 LOC110578369 LOC110578369 PSMB4 PSMB4 PSMD4 PSMD4 LYN LYN CARD11 CARD11 GAB2 GAB2 LOC110591113 LOC110591113 PSMA2 PSMA2 UBE2D2 UBE2D2 LOC110592210 LOC110592210 TXK TXK PSMD7 PSMD7 PSMD14 PSMD14 LOC110592156 LOC110592156 FBXW11 FBXW11 LAT2 LAT2 LOC110591392 LOC110591392 SKP1 SKP1 LOC110591391 LOC110591391 PIK3R1 PIK3R1 MAP3K1 MAP3K1 PPP3CB PPP3CB LOC110590956 LOC110590956 TEC TEC WDR92 WDR92 PPP3R1 PPP3R1 PSMA3 PSMA3 PSMC6 PSMC6 PSME4 PSME4 RPS27A RPS27A PSMD8 PSMD8 PSMC4 PSMC4 MAPK3 MAPK3 LAT LAT LCP2 LCP2 SPNS1 SPNS1 MAPK8 MAPK8 PSMD9 PSMD9 CHUK CHUK UBE2D1 UBE2D1 LOC110587380 LOC110587380 SOS1 SOS1 LOC110588689 LOC110588689 LOC110588252 LOC110588252 PDPK1 PDPK1 PSME2 PSME2 PSMB11 PSMB11 BTK BTK PSMB5 PSMB5 FOSL2 FOSL2 ITK ITK NFKBIA NFKBIA LOC110586587 LOC110586587 MAP2K4 MAP2K4 PRKCQ PRKCQ LOC110586377 LOC110586377 SYK SYK PSMA6 PSMA6 PSME1 PSME1 SPNS3 SPNS3 PSMD6 PSMD6 PAK2 PAK2 PSMB6 PSMB6 MAP3K7 MAP3K7 PSMB1 PSMB1 PSMD5 PSMD5 PSMB7 PSMB7 VAV2 VAV2 TAB2 TAB2 LOC110583235 LOC110583235 CUL1 CUL1 PSMD1 PSMD1 PSMD2 PSMD2 PSMA5 PSMA5 PIK3CA PIK3CA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
HRASGTPase HRas isoform X1. (189 aa)
BCL10B-cell lymphoma/leukemia 10 isoform X1. (233 aa)
NRASGTPase NRas. (189 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
KRASGTPase KRas. (188 aa)
VAV3Guanine nucleotide exchange factor VAV3. (847 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PSMB10Proteasome subunit beta. (273 aa)
NFAT5Nuclear factor of activated T-cells 5 isoform X1. (1546 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20 isoform X1. (800 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1075 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (536 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11 isoform X1. (426 aa)
LOC110592969Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (440 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1200 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
PSMF1Proteasome inhibitor PI31 subunit. (271 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1289 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC110577584Death domain-containing membrane protein NRADD-like isoform X1. (250 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (504 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
CLNKCytokine-dependent hematopoietic cell linker. (460 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
PSMC526S protease regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
PSMA7Proteasome endopeptidase complex. (238 aa)
ERASGTPase ERas. (233 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
FOSProto-oncogene c-Fos. (380 aa)
PIK3CBLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
PPP3CASerine/threonine-protein phosphatase. (526 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X4. (987 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
LOC110573367Fc receptor-like protein 3. (770 aa)
FCER1AHigh affinity immunoglobulin epsilon receptor subunit alpha. (260 aa)
LOC110573363LOW QUALITY PROTEIN: Fc receptor-like protein 2. (464 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
LOC110574051Proteasome subunit alpha type. (250 aa)
IKBKGNF-kappa-B essential modulator. (419 aa)
PSME3Proteasome activator complex subunit 3. (254 aa)
FCRL2Fc receptor-like protein 2. (549 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
LOC110573364Fc receptor-like protein 1. (398 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
JUNTranscription factor AP-1 isoform X1; Belongs to the bZIP family. (335 aa)
CCDC71LCoiled-coil domain-containing protein 71L. (234 aa)
KXD1kxDL motif-containing protein 1. (176 aa)
PSMB9Proteasome subunit beta. (209 aa)
LOC110574299Uncharacterized protein LOC110574299. (303 aa)
MS4A2High affinity immunoglobulin epsilon receptor subunit beta. (242 aa)
MS4A1B-lymphocyte antigen CD20. (297 aa)
PSMB2Proteasome subunit beta. (201 aa)
RELATranscription factor p65. (531 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2. (920 aa)
PSMB8Proteasome subunit beta. (276 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1 isoform X1. (147 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (439 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (839 aa)
LOC110575869Membrane-spanning 4-domains subfamily A member 15. (241 aa)
LOC110575868LOW QUALITY PROTEIN: membrane-spanning 4-domains subfamily A member 8-like. (252 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MS4A4ALOW QUALITY PROTEIN: membrane-spanning 4-domains subfamily A member 4A. (235 aa)
LOC110576171Membrane-spanning 4-domains subfamily A member 12-like. (263 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
HARBI1Putative nuclease HARBI1. (349 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (891 aa)
PSMA8Proteasome subunit alpha type. (262 aa)
GRAP2GRB2-related adapter protein 2. (316 aa)
LOC110578369Immunoglobulin lambda-like polypeptide 5. (212 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4. (377 aa)
LYNTyrosine-protein kinase. (512 aa)
CARD11Caspase recruitment domain-containing protein 11. (455 aa)
GAB2GRB2-associated-binding protein 2. (678 aa)
LOC110591113Ankyrin repeat and KH domain-containing protein 1 isoform X2. (2540 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC110592210Calmodulin-like; Belongs to the calmodulin family. (149 aa)
TXKTyrosine-protein kinase. (527 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
LOC110592156Calmodulin-like; Belongs to the calmodulin family. (98 aa)
FBXW11F-box/WD repeat-containing protein 11. (515 aa)
LAT2Linker for activation of T-cells family member 2 isoform X1. (218 aa)
LOC110591392Mitogen-activated protein kinase. (300 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
LOC110591391Mitogen-activated protein kinase 10-like. (176 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1393 aa)
PPP3CBSerine/threonine-protein phosphatase. (527 aa)
LOC110590956ubiquitin-40S ribosomal protein S27a-like. (154 aa)
TECTyrosine-protein kinase. (630 aa)
WDR92WD repeat-containing protein 92. (357 aa)
PPP3R1Calcineurin subunit B type 1. (170 aa)
PSMA3Proteasome subunit alpha type. (265 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PSME4Proteasome activator complex subunit 4 isoform X1. (1843 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
LATLinker for activation of T-cells family member 1. (256 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
SPNS1Protein spinster homolog 1 isoform X1. (528 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9. (223 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
LOC110587380Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
LOC110588689ubiquitin-40S ribosomal protein S27a-like. (154 aa)
LOC110588252Ubiquitin. (77 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (571 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
PSMB11Proteasome subunit beta. (285 aa)
BTKTyrosine-protein kinase. (659 aa)
PSMB5Proteasome subunit beta. (263 aa)
FOSL2Fos-related antigen 2. (325 aa)
ITKTyrosine-protein kinase. (620 aa)
NFKBIANF-kappa-B inhibitor alpha. (314 aa)
LOC110586587Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (400 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
LOC110586377ubiquitin-60S ribosomal protein L40-like. (162 aa)
SYKTyrosine-protein kinase. (635 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
SPNS3Protein spinster homolog 3. (380 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (389 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PSMB6Proteasome subunit beta. (239 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
PSMB7Proteasome subunit beta. (277 aa)
VAV2Guanine nucleotide exchange factor VAV2. (862 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
LOC11058323526S protease regulatory subunit 4-like; Belongs to the AAA ATPase family. (440 aa)
CUL1Cullin-1 isoform X1; Belongs to the cullin family. (801 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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