STRINGSTRING
MAP2K2 MAP2K2 FNDC3B FNDC3B DNM2 DNM2 SCN8A SCN8A CNTN1 CNTN1 SCN10A SCN10A LOC110584359 LOC110584359 LOC110584364 LOC110584364 MAP2K1 MAP2K1 DNM1 DNM1 VAV2 VAV2 ALCAM ALCAM AP2A2 AP2A2 HMCN2 HMCN2 FNDC3A FNDC3A CLTA CLTA LOC110579826 LOC110579826 LOC110579825 LOC110579825 MAPK1 MAPK1 IQANK1 IQANK1 CNTN2 CNTN2 LOC110578994 LOC110578994 MCMDC2 MCMDC2 NFASC NFASC LOC110577888 LOC110577888 LAMA1 LAMA1 DCX DCX ANK2 ANK2 DNM3 DNM3 NRCAM NRCAM LAMC1 LAMC1 LYPLA2 LYPLA2 LOC110573163 LOC110573163 LOC110573141 LOC110573141 HMCN1 HMCN1 SH3GL2 SH3GL2 CNTNAP1 CNTNAP1 LOC110572955 LOC110572955 AP2A1 AP2A1 VSIG10L VSIG10L AP2S1 AP2S1 MSN MSN NCAM2 NCAM2 SCN4A SCN4A ANKRD60 ANKRD60 GAP43 GAP43 AP2M1 AP2M1 CNTNAP2 CNTNAP2 CHL1 CHL1 CNTNAP5 CNTNAP5 RDX RDX CNTN6 CNTN6 ANKDD1B ANKDD1B ANK3 ANK3 CLHC1 CLHC1 SHTN1 SHTN1 CNTNAP4 CNTNAP4 CLTC CLTC AP2B1 AP2B1 PAK1 PAK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1208 aa)
DNM2Dynamin-2 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
CNTN1Contactin-1. (627 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1959 aa)
LOC110584359Contactin-associated protein-like 3. (1222 aa)
LOC110584364LOW QUALITY PROTEIN: neural cell adhesion molecule L1-like. (775 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
DNM1LOW QUALITY PROTEIN: dynamin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (867 aa)
VAV2Guanine nucleotide exchange factor VAV2. (862 aa)
ALCAMCD166 antigen isoform X1. (583 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (936 aa)
HMCN2Hemicentin-2. (4619 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1199 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (218 aa)
LOC110579826Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (299 aa)
LOC110579825Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1872 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
IQANK1Putative IQ motif and ankyrin repeat domain-containing protein LOC642574 homolog. (496 aa)
CNTN2Contactin-2. (1040 aa)
LOC110578994Neural cell adhesion molecule L1-like. (133 aa)
MCMDC2MCM domain-containing protein 2. (681 aa)
NFASCNeurofascin isoform X1. (1228 aa)
LOC110577888Hemicentin-2-like. (257 aa)
LAMA1LOW QUALITY PROTEIN: laminin subunit alpha-1. (3077 aa)
DCXNeuronal migration protein doublecortin. (396 aa)
ANK2Ankyrin-2. (4016 aa)
DNM3Dynamin-3 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (871 aa)
NRCAMNeuronal cell adhesion molecule isoform X1. (1211 aa)
LAMC1Laminin subunit gamma-1. (1529 aa)
LYPLA2Acyl-protein thioesterase 2 isoform X1. (237 aa)
LOC110573163Ankyrin-1-like isoform X1. (156 aa)
LOC110573141LOW QUALITY PROTEIN: ankyrin-1-like. (1896 aa)
HMCN1Hemicentin-1. (5635 aa)
SH3GL2endophilin-A1. (317 aa)
CNTNAP1Contactin-associated protein 1. (1383 aa)
LOC110572955Fibronectin type III domain containing protein 3C1-like. (1437 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
VSIG10LV-set and immunoglobulin domain-containing protein 10-like. (884 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
MSNMoesin. (577 aa)
NCAM2Neural cell adhesion molecule 2. (837 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1818 aa)
ANKRD60Ankyrin repeat domain-containing protein 60. (243 aa)
GAP43Neuromodulin. (242 aa)
AP2M1AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
CNTNAP2Contactin-associated protein-like 2. (1316 aa)
CHL1Neural cell adhesion molecule L1-like protein. (1225 aa)
CNTNAP5Contactin-associated protein-like 5. (1305 aa)
RDXRadixin. (583 aa)
CNTN6LOW QUALITY PROTEIN: contactin-6. (1030 aa)
ANKDD1BAnkyrin repeat and death domain-containing protein 1B. (525 aa)
ANK3Ankyrin-3 isoform X1. (4407 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (586 aa)
SHTN1Shootin-1 isoform X1. (631 aa)
CNTNAP4Contactin-associated protein-like 4 isoform X1. (1220 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
AP2B1AP complex subunit beta. (951 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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