STRINGSTRING
UBA52 UBA52 WNT4 WNT4 PSMA1 PSMA1 PSMB8 PSMB8 PSMC3 PSMC3 FZD4 FZD4 PSMA8 PSMA8 FZD8 FZD8 PSMB4 PSMB4 LOC110578691 LOC110578691 PSMD4 PSMD4 PRKCB PRKCB PSMB11 PSMB11 PSMB5 PSMB5 PFN1 PFN1 LOC110586377 LOC110586377 ROR2 ROR2 PRICKLE2 PRICKLE2 PSMA6 PSMA6 PSME1 PSME1 WNT5A WNT5A PSMF1 PSMF1 PSMD6 PSMD6 AP2M1 AP2M1 PSMB6 PSMB6 DVL2 DVL2 DAAM2 DAAM2 PSMB1 PSMB1 PSMD5 PSMD5 PSMB7 PSMB7 LOC110583235 LOC110583235 PSMD1 PSMD1 PSMD2 PSMD2 DVL3 DVL3 PSMA5 PSMA5 PSMD13 PSMD13 AP2A2 AP2A2 PRICKLE4 PRICKLE4 CLTA CLTA WNT5B WNT5B PSMC2 PSMC2 FZD6 FZD6 FZD1 FZD1 RAC2 RAC2 AP2B1 AP2B1 CLTC CLTC DAAM1 DAAM1 PARD6A PARD6A PSMA2 PSMA2 PSMD7 PSMD7 PSMD14 PSMD14 PSMA3 PSMA3 PSMC6 PSMC6 PSME4 PSME4 CLTB CLTB RPS27A RPS27A PSMD8 PSMD8 PSMC4 PSMC4 PSMD9 PSMD9 LOC110588689 LOC110588689 FHDC1 FHDC1 FZD3 FZD3 PSME2 PSME2 PSMB10 PSMB10 FZD7 FZD7 FZD5 FZD5 PSMD3 PSMD3 PSMB3 PSMB3 PSMD11 PSMD11 WNT11 WNT11 WNT1 WNT1 PRICKLE1 PRICKLE1 SMURF2 SMURF2 PSMD12 PSMD12 PSMC5 PSMC5 PSMA7 PSMA7 PRKCA PRKCA PSMD10 PSMD10 PRICKLE3 PRICKLE3 PSMC1 PSMC1 SMURF1 SMURF1 RAC1 RAC1 PSMA4 PSMA4 RAC3 RAC3 ROR1 ROR1 AP2S1 AP2S1 AP2A1 AP2A1 FZD2 FZD2 LOC110574051 LOC110574051 PSME3 PSME3 PRKCG PRKCG DVL1 DVL1 PSMB9 PSMB9 PSMB2 PSMB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (424 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (439 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
PSMA8Proteasome subunit alpha type. (262 aa)
FZD8Frizzled-8. (243 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
LOC110578691Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (338 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4. (377 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
PSMB11Proteasome subunit beta. (285 aa)
PSMB5Proteasome subunit beta. (263 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
LOC110586377ubiquitin-60S ribosomal protein L40-like. (162 aa)
ROR2Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (924 aa)
PRICKLE2LOW QUALITY PROTEIN: prickle-like protein 2. (901 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PSMF1Proteasome inhibitor PI31 subunit. (271 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (389 aa)
AP2M1AP-2 complex subunit mu isoform X1; Belongs to the adaptor complexes medium subunit family. (435 aa)
PSMB6Proteasome subunit beta. (239 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (734 aa)
DAAM2LOW QUALITY PROTEIN: disheveled-associated activator of morphogenesis 2. (1067 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
PSMB7Proteasome subunit beta. (277 aa)
LOC11058323526S protease regulatory subunit 4-like; Belongs to the AAA ATPase family. (440 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (718 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (936 aa)
PRICKLE4Prickle-like protein 4. (387 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (218 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (648 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
AP2B1AP complex subunit beta. (951 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
DAAM1Disheveled-associated activator of morphogenesis 1. (1068 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (346 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (324 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
PSMA3Proteasome subunit alpha type. (265 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PSME4Proteasome activator complex subunit 4 isoform X1. (1843 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (211 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9. (223 aa)
LOC110588689ubiquitin-40S ribosomal protein S27a-like. (154 aa)
FHDC1FH2 domain-containing protein 1. (1140 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
PSMB10Proteasome subunit beta. (273 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (536 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11 isoform X1. (426 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PRICKLE1Prickle-like protein 1. (870 aa)
SMURF2E3 ubiquitin-protein ligase. (736 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
PSMC526S protease regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
PSMA7Proteasome endopeptidase complex. (238 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
PRICKLE3Prickle-like protein 3. (613 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
SMURF1E3 ubiquitin-protein ligase. (731 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (195 aa)
ROR1Inactive tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (928 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
LOC110574051Proteasome subunit alpha type. (250 aa)
PSME3Proteasome activator complex subunit 3. (254 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa)
PSMB9Proteasome subunit beta. (209 aa)
PSMB2Proteasome subunit beta. (201 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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