STRINGSTRING
BAIAP2 BAIAP2 SHE SHE SPHK1 SPHK1 ACTG1 ACTG1 NCF2 NCF2 AKT3 AKT3 SH2D2A SH2D2A HSH2D HSH2D PIK3R2 PIK3R2 STX12 STX12 WASF2 WASF2 MAPKAPK2 MAPKAPK2 MAPK13 MAPK13 PRKCZ PRKCZ MAPK14 MAPK14 ACTL8 ACTL8 VAV1 VAV1 LPXN LPXN MTOR MTOR CDC42 CDC42 ROCK1 ROCK1 PAK3 PAK3 NCKAP1L NCKAP1L CTNND1 CTNND1 NCF4 NCF4 MAPK12 MAPK12 ABI1 ABI1 PRKCB PRKCB MAPKAPK3 MAPKAPK3 PLCG1 PLCG1 TRIB3 TRIB3 SRC SRC MAPK11 MAPK11 CSDE1 CSDE1 THEM4 THEM4 VAV3 VAV3 PRKACB PRKACB PTK2 PTK2 KRAS KRAS ARVCF ARVCF ITGB3 ITGB3 CTNNB1 CTNNB1 PTK6 PTK6 SRMS SRMS ERAS ERAS CASS4 CASS4 ELMO2 ELMO2 FNDC3A FNDC3A MAPKAP1 MAPKAP1 SHB SHB LOC110580337 LOC110580337 NRAS NRAS HRAS HRAS PIK3CA PIK3CA SHD SHD CRK CRK PXN PXN ITGAV ITGAV CDH5 CDH5 PRKACA PRKACA SHC2 SHC2 ABI2 ABI2 FNDC3B FNDC3B LOC110591514 LOC110591514 PAK1 PAK1 NCF1 NCF1 PIK3R1 PIK3R1 RASA1 RASA1 KDR KDR ELMO1 ELMO1 AXL AXL HSPB1 HSPB1 RICTOR RICTOR MLST8 MLST8 CAV1 CAV1 PTK2B PTK2B PDPK1 PDPK1 CYFIP2 CYFIP2 ROCK2 ROCK2 LOC110585088 LOC110585088 CAV3 CAV3 NEDD9 NEDD9 LOC110586587 LOC110586587 FYN FYN LOC110583825 LOC110583825 EFS EFS SHF SHF WASF1 WASF1 BRK1 BRK1 PRKCD PRKCD PAK2 PAK2 RNF222 RNF222 VEGFA VEGFA VAV2 VAV2 STX7 STX7 NOS3 NOS3 BCAR1 BCAR1 ACTBL2 ACTBL2 ELMO3 ELMO3 LOC110592210 LOC110592210 AKT2 AKT2 NCKAP1 NCKAP1 LOC110592156 LOC110592156 TGFB1I1 TGFB1I1 WASF3 WASF3 PRKCA PRKCA NCK1 NCK1 PIK3CB PIK3CB CALM1 CALM1 NCK2 NCK2 CYFIP1 CYFIP1 AKT1 AKT1 LOC110572955 LOC110572955 ACTB ACTB JUP JUP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (535 aa)
SHESH2 domain-containing adapter protein E. (453 aa)
SPHK1Sphingosine kinase 1 isoform X1. (487 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
NCF2Neutrophil cytosol factor 2. (526 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
SH2D2ASH2 domain-containing protein 2A. (399 aa)
HSH2DHematopoietic SH2 domain-containing protein. (359 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
STX12Syntaxin-12; Belongs to the syntaxin family. (326 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (499 aa)
MAPKAPK2MAP kinase-activated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (402 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (366 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
LPXNLeupaxin; Belongs to the paxillin family. (386 aa)
MTORSerine/threonine-protein kinase mTOR. (2557 aa)
CDC42Cell division control protein 42 homolog. (191 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
PAK3Non-specific serine/threonine protein kinase. (544 aa)
NCKAP1LNck-associated protein 1-like. (1134 aa)
CTNND1Catenin delta-1 isoform X4. (1016 aa)
NCF4Neutrophil cytosol factor 4. (339 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
ABI1Abl interactor 1 isoform X8. (507 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (384 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1289 aa)
TRIB3Tribbles homolog 3. (358 aa)
SRCTyrosine-protein kinase. (536 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
THEM4Acyl-coenzyme A thioesterase THEM4 isoform X1. (238 aa)
VAV3Guanine nucleotide exchange factor VAV3. (847 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1055 aa)
KRASGTPase KRas. (188 aa)
ARVCFArmadillo repeat protein deleted in velo-cardio-facial syndrome isoform X1. (960 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
CTNNB1Catenin beta-1. (781 aa)
PTK6Tyrosine-protein kinase. (486 aa)
SRMSTyrosine-protein kinase. (493 aa)
ERASGTPase ERas. (233 aa)
CASS4Cas scaffolding protein family member 4. (786 aa)
ELMO2Engulfment and cell motility protein 2. (720 aa)
FNDC3AFibronectin type-III domain-containing protein 3A. (1199 aa)
MAPKAP1Target of rapamycin complex 2 subunit MAPKAP1 isoform X1. (522 aa)
SHBSH2 domain-containing adapter protein B isoform X1. (508 aa)
LOC110580337Proline-rich protein 5. (389 aa)
NRASGTPase NRas. (189 aa)
HRASGTPase HRas isoform X1. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SHDSH2 domain-containing adapter protein D. (340 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
PXNPaxillin isoform X1; Belongs to the paxillin family. (599 aa)
ITGAVIntegrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1047 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
SHC2SHC-transforming protein 2. (551 aa)
ABI2Abl interactor 2. (475 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1208 aa)
LOC110591514Cytochrome b-245 light chain. (190 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
NCF1Neutrophil cytosol factor 1 isoform X1. (391 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
RASA1Ras GTPase-activating protein 1 isoform X1. (1039 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
ELMO1Engulfment and cell motility protein 1. (727 aa)
AXLTyrosine-protein kinase receptor UFO isoform X1. (887 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
RICTORRapamycin-insensitive companion of mTOR isoform X1. (1447 aa)
MLST8Target of rapamycin complex subunit LST8 isoform X1. (346 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1010 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (571 aa)
CYFIP2Cytoplasmic FMR1-interacting protein 2. (975 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1391 aa)
LOC110585088Rapamycin-insensitive companion of mTOR-like. (178 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
NEDD9Enhancer of filamentation 1. (834 aa)
LOC110586587Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
FYNTyrosine-protein kinase. (537 aa)
LOC110583825Cytoplasmic FMR1-interacting protein 2-like. (102 aa)
EFSEmbryonal Fyn-associated substrate isoform X1. (561 aa)
SHFSH2 domain-containing adapter protein F isoform X1. (442 aa)
WASF1wiskott-Aldrich syndrome protein family member 1 isoform X1. (559 aa)
BRK1Protein BRICK1. (75 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
RNF222RING finger protein 222. (206 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (549 aa)
VAV2Guanine nucleotide exchange factor VAV2. (862 aa)
STX7Syntaxin-7; Belongs to the syntaxin family. (261 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1202 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1. (865 aa)
ACTBL2Beta-actin-like protein 2 isoform X1. (376 aa)
ELMO3Engulfment and cell motility protein 3 isoform X1. (756 aa)
LOC110592210Calmodulin-like; Belongs to the calmodulin family. (149 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NCKAP1Nck-associated protein 1 isoform X1. (1128 aa)
LOC110592156Calmodulin-like; Belongs to the calmodulin family. (98 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (464 aa)
WASF3wiskott-Aldrich syndrome protein family member 3. (502 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
NCK1Cytoplasmic protein. (377 aa)
PIK3CBLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
NCK2Cytoplasmic protein. (380 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
LOC110572955Fibronectin type III domain containing protein 3C1-like. (1437 aa)
ACTBActin, cytoplasmic 1. (375 aa)
JUPJunction plakoglobin. (744 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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