STRINGSTRING
ACTB ACTB GRB2 GRB2 ACTG1 ACTG1 ARPC5 ARPC5 FMN2 FMN2 WASF2 WASF2 ACTL8 ACTL8 CDC42 CDC42 NCKAP1L NCKAP1L ARPC4 ARPC4 NCKIPSD NCKIPSD ABI1 ABI1 LOC110577769 LOC110577769 MAPK1 MAPK1 WIPF3 WIPF3 PTK2 PTK2 WASHC1 WASHC1 ABL1 ABL1 ARPC5L ARPC5L BRK1 BRK1 ACTR3B ACTR3B WASF3 WASF3 WAS WAS ARPC1A ARPC1A WASF1 WASF1 WIPF2 WIPF2 FMN1 FMN1 LOC110583825 LOC110583825 ACTR3 ACTR3 CYFIP2 CYFIP2 BTK BTK ACTR2 ACTR2 WASL WASL MAPK3 MAPK3 NCKAP1 NCKAP1 ACTBL2 ACTBL2 CYFIP1 CYFIP1 ARPC1B ARPC1B NCK1 NCK1 ARPC2 ARPC2 ABI2 ABI2 WIPF1 WIPF1 BAIAP2 BAIAP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACTBActin, cytoplasmic 1. (375 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
FMN2Formin-2. (982 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (499 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (366 aa)
CDC42Cell division control protein 42 homolog. (191 aa)
NCKAP1LNck-associated protein 1-like. (1134 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
NCKIPSDNCK-interacting protein with SH3 domain isoform X2. (725 aa)
ABI1Abl interactor 1 isoform X8. (507 aa)
LOC110577769Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
WIPF3WAS/WASL-interacting protein family member 3. (351 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1055 aa)
WASHC1WASH complex subunit 1 isoform X1. (473 aa)
ABL1Tyrosine-protein kinase. (1137 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
BRK1Protein BRICK1. (75 aa)
ACTR3BActin-related protein 3B isoform X1; Belongs to the actin family. (418 aa)
WASF3wiskott-Aldrich syndrome protein family member 3. (502 aa)
WASwiskott-Aldrich syndrome protein. (410 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
WASF1wiskott-Aldrich syndrome protein family member 1 isoform X1. (559 aa)
WIPF2WAS/WASL-interacting protein family member 2. (440 aa)
FMN1Formin-1 isoform X1. (1419 aa)
LOC110583825Cytoplasmic FMR1-interacting protein 2-like. (102 aa)
ACTR3Actin-related protein 3; Belongs to the actin family. (418 aa)
CYFIP2Cytoplasmic FMR1-interacting protein 2. (975 aa)
BTKTyrosine-protein kinase. (659 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (505 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
NCKAP1Nck-associated protein 1 isoform X1. (1128 aa)
ACTBL2Beta-actin-like protein 2 isoform X1. (376 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (375 aa)
NCK1Cytoplasmic protein. (377 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
ABI2Abl interactor 2. (475 aa)
WIPF1WAS/WASL-interacting protein family member 1. (492 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (535 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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