20 items (Neomonachus schauinslandi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOS1	Son of sevenless homolog 1. (1333 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	NRAS	GTPase NRas. (189 aa)
	KRAS	GTPase KRas. (188 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
	CCKBR	LOW QUALITY PROTEIN: gastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family. (455 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (744 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (740 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	GAST	Gastrin. (104 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
	ERAS	GTPase ERas. (233 aa)
	EGFR	Receptor protein-tyrosine kinase. (1207 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1. (327 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	LOC110586166	Stromelysin-1. (476 aa)
	MAPK7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (727 aa)

Your Current Organism:

Neomonachus schauinslandi

NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCKBR	GAST	A0A2Y9GVU0	A0A2Y9GEE5	LOW QUALITY PROTEIN: gastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family.	Gastrin.	0.997
CREB1	EGFR	A0A2Y9I4T9	A0A2Y9I6V3	Cyclic AMP-responsive element-binding protein 1.	Receptor protein-tyrosine kinase.	0.473
CREB1	MAPK1	A0A2Y9I4T9	A0A2Y9H0I4	Cyclic AMP-responsive element-binding protein 1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.949
CREB1	MAPK3	A0A2Y9I4T9	A0A2Y9HX44	Cyclic AMP-responsive element-binding protein 1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.929
CREB1	MAPK7	A0A2Y9I4T9	A0A2Y9HF68	Cyclic AMP-responsive element-binding protein 1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.588
CREB1	PRKCA	A0A2Y9I4T9	A0A2Y9G7H4	Cyclic AMP-responsive element-binding protein 1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.863
CREB1	RPS6KA1	A0A2Y9I4T9	A0A2Y9GKX3	Cyclic AMP-responsive element-binding protein 1.	Ribosomal protein S6 kinase.	0.694
CREB1	RPS6KA2	A0A2Y9I4T9	A0A2Y9HAU3	Cyclic AMP-responsive element-binding protein 1.	Ribosomal protein S6 kinase.	0.637
CREB1	RPS6KA3	A0A2Y9I4T9	A0A2Y9GFH9	Cyclic AMP-responsive element-binding protein 1.	Ribosomal protein S6 kinase.	0.682
CSDE1	EGFR	A0A2Y9H2J4	A0A2Y9I6V3	Cold shock domain-containing protein E1 isoform X1.	Receptor protein-tyrosine kinase.	0.456
CSDE1	GRB2	A0A2Y9H2J4	A0A2Y9GF83	Cold shock domain-containing protein E1 isoform X1.	Growth factor receptor-bound protein 2.	0.591
CSDE1	MAPK1	A0A2Y9H2J4	A0A2Y9H0I4	Cold shock domain-containing protein E1 isoform X1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.408
CSDE1	MAPK3	A0A2Y9H2J4	A0A2Y9HX44	Cold shock domain-containing protein E1 isoform X1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.408
CSDE1	RPS6KA1	A0A2Y9H2J4	A0A2Y9GKX3	Cold shock domain-containing protein E1 isoform X1.	Ribosomal protein S6 kinase.	0.462
CSDE1	RPS6KA2	A0A2Y9H2J4	A0A2Y9HAU3	Cold shock domain-containing protein E1 isoform X1.	Ribosomal protein S6 kinase.	0.464
CSDE1	RPS6KA3	A0A2Y9H2J4	A0A2Y9GFH9	Cold shock domain-containing protein E1 isoform X1.	Ribosomal protein S6 kinase.	0.462
CSDE1	SOS1	A0A2Y9H2J4	A0A2Y9HT35	Cold shock domain-containing protein E1 isoform X1.	Son of sevenless homolog 1.	0.634
EGFR	CREB1	A0A2Y9I6V3	A0A2Y9I4T9	Receptor protein-tyrosine kinase.	Cyclic AMP-responsive element-binding protein 1.	0.473
EGFR	CSDE1	A0A2Y9I6V3	A0A2Y9H2J4	Receptor protein-tyrosine kinase.	Cold shock domain-containing protein E1 isoform X1.	0.456
EGFR	ERAS	A0A2Y9I6V3	A0A2Y9G6Q7	Receptor protein-tyrosine kinase.	GTPase ERas.	0.570