32 items (Neomonachus schauinslandi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

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protein homology

Your Input:
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	FLT3	Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
	ERAS	GTPase ERas. (233 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	FLT3LG	Fms-related tyrosine kinase 3 ligand isoform X2. (301 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	ABL2	Tyrosine-protein kinase. (1182 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta. (1089 aa)
	UBA52	ubiquitin-60S ribosomal protein L40. (128 aa)
	SOCS6	Suppressor of cytokine signaling 6. (535 aa)
	GRAP2	GRB2-related adapter protein 2. (316 aa)
	SLA2	Src-like-adapter 2. (276 aa)
	SOCS2	Suppressor of cytokine signaling 2. (198 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	KRAS	GTPase KRas. (188 aa)
	SLA	Src-like-adapter. (315 aa)
	NRAS	GTPase NRas. (189 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	FOXO3	Forkhead box protein O3. (672 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	SYK	Tyrosine-protein kinase. (635 aa)
	LOC110586377	ubiquitin-60S ribosomal protein L40-like. (162 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (910 aa)
	SH2B3	SH2B adapter protein 3. (578 aa)
	LOC110588689	ubiquitin-40S ribosomal protein S27a-like. (154 aa)
	SOS1	Son of sevenless homolog 1. (1333 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	GRB10	Growth factor receptor-bound protein 10. (643 aa)
	GAB2	GRB2-associated-binding protein 2. (678 aa)

Your Current Organism:

Neomonachus schauinslandi

NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL2	CBL	A0A2Y9GH84	A0A2Y9HQP6	Tyrosine-protein kinase.	E3 ubiquitin-protein ligase CBL.	0.814
ABL2	FLT3	A0A2Y9GH84	A0A2Y9G4X7	Tyrosine-protein kinase.	Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.583
ABL2	GRAP2	A0A2Y9GH84	A0A2Y9GVU9	Tyrosine-protein kinase.	GRB2-related adapter protein 2.	0.486
ABL2	GRB2	A0A2Y9GH84	A0A2Y9GF83	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2.	0.809
AKT1	AKT3	A0A2Y9GCY3	A0A2Y9GHB6	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.790
AKT1	FOXO3	A0A2Y9GCY3	A0A2Y9HCJ4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O3.	0.899
AKT1	PIK3CA	A0A2Y9GCY3	A0A2Y9H8I3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.886
AKT1	PIK3R1	A0A2Y9GCY3	A0A2Y9I1U1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.875
AKT2	AKT3	A0A2Y9I541	A0A2Y9GHB6	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.790
AKT2	CSK	A0A2Y9I541	A0A2Y9HIQ2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.401
AKT2	FOXO3	A0A2Y9I541	A0A2Y9HCJ4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O3.	0.899
AKT2	PIK3CA	A0A2Y9I541	A0A2Y9H8I3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.886
AKT2	PIK3R1	A0A2Y9I541	A0A2Y9I1U1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.875
AKT3	AKT1	A0A2Y9GHB6	A0A2Y9GCY3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.790
AKT3	AKT2	A0A2Y9GHB6	A0A2Y9I541	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.790
AKT3	FOXO3	A0A2Y9GHB6	A0A2Y9HCJ4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O3.	0.958
AKT3	PIK3CA	A0A2Y9GHB6	A0A2Y9H8I3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.959
AKT3	PIK3R1	A0A2Y9GHB6	A0A2Y9I1U1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.955
CBL	ABL2	A0A2Y9HQP6	A0A2Y9GH84	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.814
CBL	CSK	A0A2Y9HQP6	A0A2Y9HIQ2	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.744