(52 nodes) Pentose and glucuronate interconversions network (Neomonachus schauinslandi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPE	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
	SUN3	SUN domain-containing protein 3. (360 aa)
	XYLB	Xylulose kinase. (536 aa)
	TRMT1	tRNA (guanine(26)-N(2))-dimethyltransferase. (628 aa)
	LOC110591360	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (247 aa)
	UGDH	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
	RIPOR1	Protein FAM65A isoform X1. (1323 aa)
	VWA3B	Von Willebrand factor A domain-containing protein 3B. (1248 aa)
	GUSB	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (648 aa)
	CUNH10orf76	UPF0668 protein C10orf76 homolog. (689 aa)
	LOC110591531	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
	LOC110591405	UDP-glucuronosyltransferase 2A2 isoform X1; Belongs to the UDP-glycosyltransferase family. (694 aa)
	SLAIN2	SLAIN motif-containing protein 2 isoform X1. (608 aa)
	EDIL3	EGF-like repeat and discoidin I-like domain-containing protein 3 isoform X1. (480 aa)
	CRIM1	Cysteine-rich motor neuron 1 protein isoform X4. (1037 aa)
	BMPER	BMP-binding endothelial regulator protein. (685 aa)
	ABCF1	ATP-binding cassette sub-family F member 1 isoform X1. (838 aa)
	UGP2	UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
	LOC110587752	Spermatid-associated protein-like. (252 aa)
	SORD	Sorbitol dehydrogenase. (356 aa)
	RIPOR2	Protein FAM65B isoform X1. (1043 aa)
	AKR1E2	1,5-anhydro-D-fructose reductase isoform X1. (301 aa)
	UBASH3B	Ubiquitin-associated and SH3 domain-containing protein B. (603 aa)
	TECTA	Alpha-tectorin. (2155 aa)
	RNASET2	Ribonuclease T2 isoform X1; Belongs to the RNase T2 family. (253 aa)
	AKR1B1	Aldose reductase. (316 aa)
	CCDC80	Coiled-coil domain-containing protein 80. (956 aa)
	NPTN	Neuroplastin. (417 aa)
	FBXO30	F-box only protein 30. (746 aa)
	FBXO40	F-box only protein 40. (742 aa)
	SPAG4	Sperm-associated antigen 4 protein isoform X1. (440 aa)
	CABIN1	Calcineurin-binding protein cabin-1. (2191 aa)
	ISPD	Isoprenoid synthase domain-containing protein isoform X1. (447 aa)
	SUN5	SUN domain-containing protein 5. (365 aa)
	SUN2	SUN domain-containing protein 2. (718 aa)
	VWA3A	Von Willebrand factor A domain-containing protein 3A. (1208 aa)
	NCAPH2	Condensin-2 complex subunit H2 isoform X1. (653 aa)
	RIPOR3	Protein FAM65C. (944 aa)
	RAI2	Retinoic acid-induced protein 2. (530 aa)
	VWCE	Von Willebrand factor C and EGF domain-containing protein. (934 aa)
	AKR1A1	Alcohol dehydrogenase [NADP(+)] isoform X1. (325 aa)
	NDP	Norrin. (133 aa)
	TRMT1L	TRMT1-like protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (734 aa)
	MFGE8	Lactadherin. (430 aa)
	BICRA	Glioma tumor suppressor candidate region gene 1 protein. (1572 aa)
	DHDH	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase. (335 aa)
	SUN1	SUN domain-containing protein 1 isoform X1. (937 aa)
	IQCE	IQ domain-containing protein E. (674 aa)
	LOC110571278	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
	UBASH3A	Ubiquitin-associated and SH3 domain-containing protein A isoform X1. (624 aa)
	LOC110570878	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
	CRYL1	Lambda-crystallin homolog. (319 aa)

Your Current Organism:

Neomonachus schauinslandi

NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKR1A1	CRYL1	A0A2Y9GK42	A0A2Y9G4U4	Alcohol dehydrogenase [NADP(+)] isoform X1.	Lambda-crystallin homolog.	0.936
AKR1A1	DHDH	A0A2Y9GK42	A0A2Y9GCX7	Alcohol dehydrogenase [NADP(+)] isoform X1.	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.	0.436
AKR1A1	GUSB	A0A2Y9GK42	A0A2Y9I3J6	Alcohol dehydrogenase [NADP(+)] isoform X1.	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	0.918
AKR1A1	SORD	A0A2Y9GK42	A0A2Y9HNI5	Alcohol dehydrogenase [NADP(+)] isoform X1.	Sorbitol dehydrogenase.	0.558
AKR1B1	DHDH	A0A2Y9HFK0	A0A2Y9GCX7	Aldose reductase.	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.	0.915
AKR1B1	SORD	A0A2Y9HFK0	A0A2Y9HNI5	Aldose reductase.	Sorbitol dehydrogenase.	0.956
AKR1E2	DHDH	A0A2Y9HL64	A0A2Y9GCX7	1,5-anhydro-D-fructose reductase isoform X1.	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.	0.822
AKR1E2	SORD	A0A2Y9HL64	A0A2Y9HNI5	1,5-anhydro-D-fructose reductase isoform X1.	Sorbitol dehydrogenase.	0.907
CRYL1	AKR1A1	A0A2Y9G4U4	A0A2Y9GK42	Lambda-crystallin homolog.	Alcohol dehydrogenase [NADP(+)] isoform X1.	0.936
CRYL1	SORD	A0A2Y9G4U4	A0A2Y9HNI5	Lambda-crystallin homolog.	Sorbitol dehydrogenase.	0.689
CRYL1	XYLB	A0A2Y9G4U4	A0A2Y9IC29	Lambda-crystallin homolog.	Xylulose kinase.	0.613
DHDH	AKR1A1	A0A2Y9GCX7	A0A2Y9GK42	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.	Alcohol dehydrogenase [NADP(+)] isoform X1.	0.436
DHDH	AKR1B1	A0A2Y9GCX7	A0A2Y9HFK0	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.	Aldose reductase.	0.915
DHDH	AKR1E2	A0A2Y9GCX7	A0A2Y9HL64	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.	1,5-anhydro-D-fructose reductase isoform X1.	0.822
DHDH	SORD	A0A2Y9GCX7	A0A2Y9HNI5	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.	Sorbitol dehydrogenase.	0.605
DHDH	UBASH3A	A0A2Y9GCX7	A0A2Y9G7F0	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.	Ubiquitin-associated and SH3 domain-containing protein A isoform X1.	0.510
DHDH	UBASH3B	A0A2Y9GCX7	A0A2Y9HKN6	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.	Ubiquitin-associated and SH3 domain-containing protein B.	0.510
DHDH	UGDH	A0A2Y9GCX7	A0A2Y9I6Q0	LOW QUALITY PROTEIN: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase.	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	0.478
GUSB	AKR1A1	A0A2Y9I3J6	A0A2Y9GK42	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	Alcohol dehydrogenase [NADP(+)] isoform X1.	0.918
GUSB	LOC110570878	A0A2Y9I3J6	A0A2Y9G6H0	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.865