(110 nodes) Amino sugar and nucleotide sugar metabolism network (Neomonachus schauinslandi)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	NAGK	N-acetyl-D-glucosamine kinase isoform X1. (344 aa)
	METTL23	Methyltransferase-like protein 23. (341 aa)
	NPL	N-acetylneuraminate lyase; Belongs to the DapA family. (320 aa)
	NIPAL3	NIPA-like protein 3. (406 aa)
	GALE	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)
	HAS1	Hyaluronan synthase 1. (583 aa)
	NIPA1	Magnesium transporter NIPA1. (324 aa)
	UXS1	UDP-glucuronic acid decarboxylase 1 isoform X1. (420 aa)
	SNX8	Sorting nexin-8 isoform X1. (463 aa)
	PGM1	Phosphoglucomutase-1; Belongs to the phosphohexose mutase family. (562 aa)
	SYP	Synaptophysin. (313 aa)
	OXNAD1	Oxidoreductase NAD-binding domain-containing protein 1 isoform X1. (312 aa)
	UBASH3A	Ubiquitin-associated and SH3 domain-containing protein A isoform X1. (624 aa)
	GLIPR1	Glioma pathogenesis-related protein 1; Belongs to the CRISP family. (270 aa)
	GLIPR1L1	GLIPR1-like protein 1; Belongs to the CRISP family. (243 aa)
	FPGT	Fucose-1-phosphate guanylyltransferase isoform X1. (599 aa)
	RABGGTB	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (353 aa)
	NIPAL4	Magnesium transporter NIPA4. (404 aa)
	SYPL1	Synaptophysin-like protein 1. (239 aa)
	MS4A14	Membrane-spanning 4-domains subfamily A member 14. (873 aa)
	LOC110575301	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (345 aa)
	LOC110576546	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (304 aa)
	PI16	Peptidase inhibitor 16; Belongs to the CRISP family. (458 aa)
	LOC110577299	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
	CHIT1	Chitotriosidase-1 isoform X1; Belongs to the glycosyl hydrolase 18 family. (462 aa)
	CHI3L1	Chitinase-3-like protein 1; Belongs to the glycosyl hydrolase 18 family. (384 aa)
	GMPPB	Mannose-1-phosphate guanyltransferase beta isoform X1. (360 aa)
	HEXB	Beta-hexosaminidase. (527 aa)
	GNPNAT1	Glucosamine 6-phosphate N-acetyltransferase. (184 aa)
	GCK	Phosphotransferase. (465 aa)
	VCPKMT	Protein-lysine methyltransferase METTL21D. (229 aa)
	UGDH	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
	LARP4	La-related protein 4. (661 aa)
	METTL21A	Protein N-lysine methyltransferase METTL21A. (239 aa)
	LOC110593554	LOW QUALITY PROTEIN: methyltransferase-like protein 7A. (151 aa)
	METTL7A	Methyltransferase-like protein 7A. (245 aa)
	SLC25A23	Calcium-binding mitochondrial carrier protein SCaMC-3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (468 aa)
	HAS3	Hyaluronan synthase 3. (554 aa)
	SLC25A41	Solute carrier family 25 member 41; Belongs to the mitochondrial carrier (TC 2.A.29) family. (369 aa)
	FUK	LOW QUALITY PROTEIN: L-fucose kinase. (1112 aa)
	RENBP	N-acylglucosamine 2-epimerase. (359 aa)
	PMM1	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (266 aa)
	LOC110576996	O-acyltransferase like protein-like. (686 aa)
	LOC110578371	N-alpha-acetyltransferase 10. (128 aa)
	R3HDML	Peptidase inhibitor R3HDML; Belongs to the CRISP family. (252 aa)
	METTL7B	Methyltransferase-like protein 7B. (244 aa)
	GLT8D2	Glycosyltransferase 8 domain-containing protein 2. (350 aa)
	GFPT2	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2. (686 aa)
	LOC110578265	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (301 aa)
	LOC110580322	Calcium-binding mitochondrial carrier protein SCaMC-1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (477 aa)
	LOC110580459	Calcium-binding mitochondrial carrier protein SCaMC-1-like; Belongs to the mitochondrial carrier (TC 2.A.29) family. (475 aa)
	CTBS	di-N-acetylchitobiase; Belongs to the glycosyl hydrolase 18 family. (375 aa)
	CHIA	LOW QUALITY PROTEIN: acidic mammalian chitinase; Belongs to the glycosyl hydrolase 18 family. (477 aa)
	CMAS	N-acylneuraminate cytidylyltransferase. (434 aa)
	HAS2	Hyaluronan synthase 2. (552 aa)
	TSTA3	GDP-L-fucose synthase isoform X1. (321 aa)
	LARP4B	La-related protein 4B isoform X1. (734 aa)
	PI15	Peptidase inhibitor 15; Belongs to the CRISP family. (258 aa)
	EDF1	Endothelial differentiation-related factor 1. (148 aa)
	NIPAL2	NIPA-like protein 2 isoform X1. (374 aa)
	IL11RA	Interleukin-11 receptor subunit alpha isoform X1. (425 aa)
	NANS	Sialic acid synthase. (359 aa)
	SLC25A25	Calcium-binding mitochondrial carrier protein SCaMC-2 isoform X2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (513 aa)
	OVGP1	LOW QUALITY PROTEIN: oviduct-specific glycoprotein; Belongs to the glycosyl hydrolase 18 family. (605 aa)
	SYPL2	Synaptophysin-like protein 2. (264 aa)
	LOC110580615	LOW QUALITY PROTEIN: calcium-binding mitochondrial carrier protein SCaMC-1-like; Belongs to the mitochondrial carrier (TC 2.A.29) family. (376 aa)
	ETFBKMT	Electron transfer flavoprotein beta subunit lysine methyltransferase. (266 aa)
	LOC110583104	Cytochrome b5 reductase 4. (520 aa)
	GALT	Galactose-1-phosphate uridylyltransferase. (388 aa)
	UAP1L1	UDP-N-acetylhexosamine pyrophosphorylase-like protein 1. (504 aa)
	GLIPR2	Golgi-associated plant pathogenesis-related protein 1; Belongs to the CRISP family. (154 aa)
	CRISP1	Cysteine-rich secretory protein 1; Belongs to the CRISP family. (252 aa)
	HEXA	Beta-hexosaminidase. (543 aa)
	LOC110581873	Galactokinase. (392 aa)
	GNE	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase. (722 aa)
	PGM5	LOW QUALITY PROTEIN: phosphoglucomutase-like protein 5; Belongs to the phosphohexose mutase family. (567 aa)
	CRISP2	Cysteine-rich secretory protein 2; Belongs to the CRISP family. (244 aa)
	LOC110582093	Cysteine-rich secretory protein 2-like isoform X1; Belongs to the CRISP family. (254 aa)
	GLT8D1	Glycosyltransferase 8 domain-containing protein 1. (369 aa)
	LMCD1	LIM and cysteine-rich domains protein 1 isoform X1. (363 aa)
	SYNPR	Synaptoporin. (285 aa)
	PGM3	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family. (541 aa)
	METTL21C	Protein-lysine methyltransferase METTL21C. (260 aa)
	MPI	Mannose-6-phosphate isomerase. (421 aa)
	FAM149A	Protein FAM149A. (482 aa)
	UBASH3B	Ubiquitin-associated and SH3 domain-containing protein B. (603 aa)
	GMDS	GDP-mannose 4,6 dehydratase. (372 aa)
	AMDHD2	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. (409 aa)
	UHMK1	Serine/threonine-protein kinase Kist. (419 aa)
	UAP1	UDP-N-acetylhexosamine pyrophosphorylase isoform X1. (522 aa)
	NIPA2	Magnesium transporter NIPA2. (360 aa)
	NFU1	NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform X1. (253 aa)
	GFPT1	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1. (820 aa)
	UGP2	UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
	HK2	Hexokinase-2. (917 aa)
	GCKR	LOW QUALITY PROTEIN: glucokinase regulatory protein. (631 aa)
	HKDC1	Putative hexokinase HKDC1 isoform X1. (917 aa)
	HK1	Hexokinase-1. (917 aa)
	PMM2	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (251 aa)
	HK3	Hexokinase-3. (924 aa)
	M1AP	Meiosis 1 arrest protein. (365 aa)
	GNPDA1	Glucosamine-6-phosphate isomerase. (289 aa)
	NIPAL1	Magnesium transporter NIPA3. (413 aa)
	FAM149B1	Protein FAM149B1. (584 aa)
	NAA11	N-alpha-acetyltransferase 11. (229 aa)
	GMPPA	Mannose-1-phosphate guanyltransferase alpha isoform X1. (424 aa)
	NANP	N-acylneuraminate-9-phosphatase. (248 aa)
	GNPDA2	Glucosamine-6-phosphate isomerase. (276 aa)
	PGM2	Phosphoglucomutase-2. (615 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)

Your Current Organism:

Neomonachus schauinslandi

NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMDHD2	FAM149A	A0A2Y9HQA4	A0A2Y9HK60	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Protein FAM149A.	0.456
AMDHD2	FAM149B1	A0A2Y9HQA4	A0A2Y9I0F4	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Protein FAM149B1.	0.456
AMDHD2	GALE	A0A2Y9HQA4	A0A2Y9GKV6	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.473
AMDHD2	GCK	A0A2Y9HQA4	A0A2Y9I688	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Phosphotransferase.	0.406
AMDHD2	GCKR	A0A2Y9HQA4	A0A2Y9HU26	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	LOW QUALITY PROTEIN: glucokinase regulatory protein.	0.952
AMDHD2	GFPT1	A0A2Y9HQA4	A0A2Y9HT83	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1.	0.948
AMDHD2	GFPT2	A0A2Y9HQA4	A0A2Y9H221	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2.	0.962
AMDHD2	GMPPA	A0A2Y9HQA4	A0A2Y9I385	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Mannose-1-phosphate guanyltransferase alpha isoform X1.	0.779
AMDHD2	GMPPB	A0A2Y9HQA4	A0A2Y9GTF7	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Mannose-1-phosphate guanyltransferase beta isoform X1.	0.725
AMDHD2	GNE	A0A2Y9HQA4	A0A2Y9HDX6	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.	0.953
AMDHD2	GNPDA1	A0A2Y9HQA4	A0A2Y9I0A6	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucosamine-6-phosphate isomerase.	0.994
AMDHD2	GNPDA2	A0A2Y9HQA4	A0A2Y9I4T5	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucosamine-6-phosphate isomerase.	0.995
AMDHD2	GNPNAT1	A0A2Y9HQA4	A0A2Y9I633	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucosamine 6-phosphate N-acetyltransferase.	0.883
AMDHD2	GPI	A0A2Y9HQA4	A0A2Y9I5E9	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.791
AMDHD2	HEXA	A0A2Y9HQA4	A0A2Y9HDP4	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Beta-hexosaminidase.	0.473
AMDHD2	HEXB	A0A2Y9HQA4	A0A2Y9I629	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Beta-hexosaminidase.	0.523
AMDHD2	HK1	A0A2Y9HQA4	A0A2Y9HWE4	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Hexokinase-1.	0.864
AMDHD2	HK2	A0A2Y9HQA4	A0A2Y9HTM5	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Hexokinase-2.	0.864
AMDHD2	HK3	A0A2Y9HQA4	A0A2Y9HYF2	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Hexokinase-3.	0.864
AMDHD2	HKDC1	A0A2Y9HQA4	A0A2Y9HV20	N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.	Putative hexokinase HKDC1 isoform X1.	0.864