STRINGSTRING
EFNA2 EFNA2 FGF22 FGF22 PLCG2 PLCG2 GNG14 GNG14 INSR INSR GNG7 GNG7 KSR1 KSR1 PRKACA PRKACA SHC2 SHC2 PLA2G1B PLA2G1B PLA2G3 PLA2G3 MAP2K2 MAP2K2 PAK1 PAK1 GAB2 GAB2 NGFR NGFR NF1 NF1 GNGT2 GNGT2 FGFR2 FGFR2 EGFR EGFR ARF6 ARF6 RALA RALA PDGFRA PDGFRA LOC110592210 LOC110592210 AKT2 AKT2 PAK4 PAK4 LOC110592156 LOC110592156 PLD1 PLD1 FGF5 FGF5 LOC110591392 LOC110591392 LOC110591391 LOC110591391 PIK3R1 PIK3R1 LOC110589822 LOC110589822 FGF1 FGF1 RASA1 RASA1 KIT KIT HTR7 HTR7 KDR KDR REL REL GNG2 GNG2 EFNA5 EFNA5 LOC110590429 LOC110590429 SOS2 SOS2 BRAP BRAP CSF1R CSF1R RASGRP4 RASGRP4 MAPK3 MAPK3 LAT LAT PLCE1 PLCE1 MAPK8 MAPK8 RASAL1 RASAL1 LOC110588046 LOC110588046 PLA2G12B PLA2G12B FGF8 FGF8 CHUK CHUK SHOC2 SHOC2 RASGRF2 RASGRF2 MET MET TGFA TGFA SOS1 SOS1 FGF17 FGF17 FGFR4 FGFR4 PDGFC PDGFC KSR2 KSR2 FGF10 FGF10 PTPN11 PTPN11 FGF18 FGF18 GNG13 GNG13 GRIN2A GRIN2A RALB RALB PLA2G4E PLA2G4E RASGRP1 RASGRP1 RASGRP3 RASGRP3 EXOC2 EXOC2 PDGFRB PDGFRB PLD2 PLD2 LOC110586587 LOC110586587 CALML5 CALML5 PDGFD PDGFD ETS1 ETS1 GNG4 GNG4 CALML4 CALML4 RASA3 RASA3 PLA2G4D PLA2G4D PLA2G4B PLA2G4B PLA2G4F PLA2G4F AFDN AFDN LOC110585438 LOC110585438 JMJD7 JMJD7 PAK6 PAK6 RAF1 RAF1 PAK2 PAK2 PLA1A PLA1A SHC3 SHC3 FGF20 FGF20 VEGFC VEGFC ANGPT2 ANGPT2 GNB5 GNB5 MAP2K1 MAP2K1 SHC4 SHC4 CEP152 CEP152 VEGFA VEGFA FGF7 FGF7 GNGT1 GNGT1 GNG5 GNG5 HRAS HRAS PIK3CA PIK3CA FLT4 FLT4 GNB4 GNB4 NTF3 NTF3 FGF23 FGF23 PRKACB PRKACB GRIN1 GRIN1 FGF6 FGF6 GALK2 GALK2 NTRK2 NTRK2 FGFR3 FGFR3 RAB17 RAB17 ERAS ERAS RAB5A RAB5A PRKCA PRKCA ETS2 ETS2 GAB1 GAB1 PGF PGF MRAS MRAS RASA2 RASA2 PIK3CB PIK3CB CALM1 CALM1 GNB2 GNB2 PDGFA PDGFA RAC1 RAC1 FOXO4 FOXO4 RAC3 RAC3 IGF1R IGF1R LOC110572425 LOC110572425 ELK1 ELK1 RPS6KL1 RPS6KL1 VEGFD VEGFD GNG8 GNG8 AKT1 AKT1 RRAS RRAS FGF21 FGF21 FLT3LG FLT3LG GNG12 GNG12 NFKB1 NFKB1 IKBKB IKBKB FGFR1 FGFR1 RAB5C RAB5C EFNA1 EFNA1 GRB2 GRB2 EFNA3 EFNA3 RASGRF1 RASGRF1 RGL1 RGL1 FGF2 FGF2 TEK TEK ABL2 ABL2 AKT3 AKT3 IKBKG IKBKG PLA2G4A PLA2G4A NTF4 NTF4 ADAM15 ADAM15 PIK3R2 PIK3R2 SHC1 SHC1 LOC110574727 LOC110574727 LOC110574730 LOC110574730 NTRK1 NTRK1 EFNA4 EFNA4 PRKCG PRKCG CALML6 CALML6 RASAL3 RASAL3 RASAL2 RASAL2 LOC110575329 LOC110575329 FASLG FASLG PLA2G12A PLA2G12A EGF EGF SYNGAP1 SYNGAP1 RGL2 RGL2 LOC110574729 LOC110574729 RELA RELA VEGFB VEGFB IGF2 IGF2 FGF3 FGF3 GNB1 GNB1 LOC110574728 LOC110574728 PIK3R3 PIK3R3 PIK3CD PIK3CD EPHA2 EPHA2 CDC42 CDC42 LOC110575926 LOC110575926 PPP1R14B PPP1R14B RIN1 RIN1 RASSF5 RASSF5 PAK3 PAK3 FGF4 FGF4 FGF19 FGF19 GNG3 GNG3 BAD BAD RASGRP2 RASGRP2 RAB5B RAB5B INS INS BDNF BDNF PLA2G6 PLA2G6 KITLG KITLG RRAS2 RRAS2 FGF16 FGF16 ANGPT1 ANGPT1 RASSF1 RASSF1 PRKCB PRKCB PLCG1 PLCG1 STK4 STK4 RAC2 RAC2 MAPK1 MAPK1 RALBP1 RALBP1 RAPGEF5 RAPGEF5 IGF1 IGF1 PDGFB PDGFB MAPK9 MAPK9 CSF1 CSF1 CSDE1 CSDE1 NGF NGF RAP1A RAP1A KRAS KRAS GRIN2B GRIN2B ANGPT4 ANGPT4 PAK5 PAK5 GNB3 GNB3 ABL1 ABL1 GNG10 GNG10 RALGDS RALGDS GNG11 GNG11 BCL2L1 BCL2L1 HGF HGF NRAS NRAS TIAM1 TIAM1 FLT1 FLT1 FGF9 FGF9 FLT3 FLT3 TBK1 TBK1 RAP1B RAP1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EFNA2ephrin-A2. (164 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (171 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1200 aa)
GNG14LOW QUALITY PROTEIN: uncharacterized LOC105372280 homolog. (100 aa)
INSRTyrosine-protein kinase receptor. (1368 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
KSR1Kinase suppressor of Ras 1. (739 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
SHC2SHC-transforming protein 2. (551 aa)
PLA2G1BPhospholipase A(2). (146 aa)
PLA2G3Group 3 secretory phospholipase A2. (522 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
GAB2GRB2-associated-binding protein 2. (678 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (419 aa)
NF1Neurofibromin isoform X1. (2841 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (118 aa)
FGFR2Fibroblast growth factor receptor. (842 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
RALARas-related protein Ral-A. (206 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
LOC110592210Calmodulin-like; Belongs to the calmodulin family. (149 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PAK4Non-specific serine/threonine protein kinase. (594 aa)
LOC110592156Calmodulin-like; Belongs to the calmodulin family. (98 aa)
PLD1Phospholipase. (1040 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa)
LOC110591392Mitogen-activated protein kinase. (300 aa)
LOC110591391Mitogen-activated protein kinase 10-like. (176 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
LOC110589822Ras GTPase-activating protein 4. (801 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
RASA1Ras GTPase-activating protein 1 isoform X1. (1039 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
HTR75-hydroxytryptamine receptor 7 isoform X1; Belongs to the G-protein coupled receptor 1 family. (448 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
RELProto-oncogene c-Rel. (594 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa)
LOC110590429Tyrosine-protein kinase. (616 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1338 aa)
BRAPBRCA1-associated protein isoform X1. (592 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (962 aa)
RASGRP4RAS guanyl-releasing protein 4. (673 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
LATLinker for activation of T-cells family member 1. (256 aa)
PLCE1Phosphoinositide phospholipase C. (2299 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
RASAL1rasGAP-activating-like protein 1. (805 aa)
LOC110588046Phospholipase A(2). (165 aa)
PLA2G12BGroup XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (238 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
SHOC2Leucine-rich repeat protein SHOC-2. (582 aa)
RASGRF2Ras-specific guanine nucleotide-releasing factor 2. (1239 aa)
METHepatocyte growth factor receptor. (1382 aa)
TGFAProtransforming growth factor alpha. (160 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FGFR4Fibroblast growth factor receptor. (800 aa)
PDGFCPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
KSR2Kinase suppressor of Ras 2. (949 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
RALBRas-related protein Ral-B. (206 aa)
PLA2G4EPhospholipase A2. (841 aa)
RASGRP1RAS guanyl-releasing protein 1. (956 aa)
RASGRP3Ras guanyl-releasing protein 3. (693 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (891 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1098 aa)
PLD2Phospholipase. (933 aa)
LOC110586587Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
CALML5Calmodulin-like protein 5. (149 aa)
PDGFDPlatelet-derived growth factor D. (335 aa)
ETS1Protein C-ets-1. (441 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like protein 4. (197 aa)
RASA3Ras GTPase-activating protein 3. (834 aa)
PLA2G4DPhospholipase A2. (817 aa)
PLA2G4BPhospholipase A2. (782 aa)
PLA2G4FPhospholipase A2. (860 aa)
AFDNAfadin isoform X1. (1791 aa)
LOC110585438Uncharacterized protein LOC110585438. (271 aa)
JMJD7jmjC domain-containing protein 7. (316 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PLA1APhospholipase A1 member A. (459 aa)
SHC3SHC-transforming protein 3. (469 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
ANGPT2Angiopoietin-2. (541 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (395 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
SHC4SHC-transforming protein 4. (630 aa)
CEP152Centrosomal protein of 152 kDa isoform X1. (1723 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (549 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
HRASGTPase HRas isoform X1. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FLT4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1405 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GALK2N-acetylgalactosamine kinase. (461 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
FGFR3Fibroblast growth factor receptor. (806 aa)
RAB17LOW QUALITY PROTEIN: ras-related protein Rab-17. (161 aa)
ERASGTPase ERas. (233 aa)
RAB5ARas-related protein Rab-5A. (215 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (724 aa)
PGFPlacenta growth factor isoform X2; Belongs to the PDGF/VEGF growth factor family. (170 aa)
MRASRas-related protein M-Ras. (132 aa)
RASA2Ras GTPase-activating protein 2 isoform X1. (850 aa)
PIK3CBLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
PDGFAPlatelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (331 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
FOXO4Forkhead box protein O4. (506 aa)
RAC3Ras-related C3 botulinum toxin substrate 3. (195 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
LOC110572425Parvalbumin beta-like. (129 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (435 aa)
RPS6KL1Ribosomal protein S6 kinase-like 1. (550 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (357 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
RRASRas-related protein R-Ras isoform X1. (218 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FLT3LGFms-related tyrosine kinase 3 ligand isoform X2. (301 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X4. (987 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (756 aa)
FGFR1Fibroblast growth factor receptor. (735 aa)
RAB5CRas-related protein Rab-5C. (216 aa)
EFNA1ephrin-A1; Belongs to the ephrin family. (205 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
EFNA3ephrin-A3 isoform X1; Belongs to the ephrin family. (232 aa)
RASGRF1Ras-specific guanine nucleotide-releasing factor 1. (1257 aa)
RGL1Ral guanine nucleotide dissociation stimulator-like 1. (768 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (374 aa)
TEKAngiopoietin-1 receptor. (1124 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
IKBKGNF-kappa-B essential modulator. (419 aa)
PLA2G4APhospholipase A2. (733 aa)
NTF4Neurotrophin-4; Belongs to the NGF-beta family. (211 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (893 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (726 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
LOC110574727Phospholipase A(2). (142 aa)
LOC110574730Phospholipase A(2). (211 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
EFNA4ephrin-A4; Belongs to the ephrin family. (204 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
CALML6Calmodulin-like protein 6. (232 aa)
RASAL3RAS protein activator like-3. (1012 aa)
RASAL2Ras GTPase-activating protein nGAP. (1111 aa)
LOC110575329Tyrosine-protein phosphatase non-receptor type 11-like. (582 aa)
FASLGTumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (281 aa)
PLA2G12AGroup XIIA secretory phospholipase A2. (190 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1197 aa)
SYNGAP1ras/Rap GTPase-activating protein SynGAP isoform X1. (1345 aa)
RGL2Ral guanine nucleotide dissociation stimulator-like 2. (778 aa)
LOC110574729Phospholipase A(2). (145 aa)
RELATranscription factor p65. (531 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
IGF2Insulin-like growth factor II isoform X1. (238 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
LOC110574728Phospholipase A(2). (137 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (507 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
CDC42Cell division control protein 42 homolog. (191 aa)
LOC110575926HRAS-like suppressor 3. (162 aa)
PPP1R14BLOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 14B-like. (203 aa)
RIN1Ras and Rab interactor 1. (782 aa)
RASSF5Ras association domain-containing protein 5 isoform X1. (417 aa)
PAK3Non-specific serine/threonine protein kinase. (544 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
BADBcl2-associated agonist of cell death isoform X1. (205 aa)
RASGRP2RAS guanyl-releasing protein 2 isoform X1. (609 aa)
RAB5BRas-related protein Rab-5B isoform X1. (215 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (247 aa)
PLA2G685/88 kDa calcium-independent phospholipase A2 isoform X3. (807 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
RRAS2Ras-related protein R-Ras2. (127 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ANGPT1Angiopoietin-1 isoform X2. (498 aa)
RASSF1Ras association domain-containing protein 1 isoform X1. (340 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (634 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1289 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X1. (192 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
RALBP1ralA-binding protein 1 isoform X1. (634 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (811 aa)
IGF1Insulin-like growth factor I isoform X1. (185 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
KRASGTPase KRas. (188 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1484 aa)
ANGPT4Angiopoietin-4. (498 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
ABL1Tyrosine-protein kinase. (1137 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
RALGDSRal guanine nucleotide dissociation stimulator isoform X1. (886 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
BCL2L1Bcl-2-like protein 1 isoform X1. (233 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
NRASGTPase NRas. (189 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1 isoform X1. (1591 aa)
FLT1Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
TBK1Serine/threonine-protein kinase TBK1 isoform X1. (729 aa)
RAP1BRas-related protein Rap-1b. (184 aa)
Your Current Organism:
Neomonachus schauinslandi
NCBI taxonomy Id: 29088
Other names: Hawaiian monk seal, Monachus schauinslandi, N. schauinslandi
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